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Featured researches published by Rebecca C Rossom.


Annals of Internal Medicine | 2013

Screening for Cognitive Impairment in Older Adults: A Systematic Review for the U.S. Preventive Services Task Force

Jennifer Lin; Elizabeth O'Connor; Rebecca C Rossom; Leslie A Perdue; Elizabeth Eckstrom

BACKGROUND Earlier identification of cognitive impairment may reduce patient and caregiver morbidity. PURPOSE To systematically review the diagnostic accuracy of brief cognitive screening instruments and the benefits and harms of pharmacologic and nonpharmacologic interventions for early cognitive impairment. DATA SOURCES MEDLINE, PsycINFO, and the Cochrane Central Register of Controlled Trials through December 2012; systematic reviews; clinical trial registries; and experts. STUDY SELECTION English-language studies of fair to good quality, primary care–feasible screening instruments, and treatments aimed at persons with mild cognitive impairment or mild to moderate dementia. DATA EXTRACTION Dual quality assessment and abstraction of relevant study details. DATA SYNTHESIS The Mini-Mental State Examination (k = 25) is the most thoroughly studied instrument but is not available for use without cost. Publicly available instruments with adequate test performance to detect dementia include the Clock Drawing Test (k = 7), Mini-Cog (k = 4), Memory Impairment Screen (k = 5), Abbreviated Mental Test (k = 4), Short Portable Mental Status Questionnaire (k = 4), Free and Cued Selective Reminding Test (k = 2), 7-Minute Screen (k = 2), and Informant Questionnaire on Cognitive Decline in the Elderly (k = 5). Medications approved by the U.S. Food and Drug Administration for Alzheimer disease (k = 58) and caregiver interventions (k = 59) show a small benefit of uncertain clinical importance for patients and their caregivers. Small benefits are also limited by common adverse effects of acetylcholinesterase inhibitors and limited availability of complex caregiver interventions. Although promising, cognitive stimulation (k = 6) and exercise (k = 10) have limited evidence to support their use in persons with mild to moderate dementia or mild cognitive impairment. LIMITATION Limited studies in persons with dementia other than Alzheimer disease and sparse reporting of important health outcomes. CONCLUSION Brief instruments to screen for cognitive impairment can adequately detect dementia, but there is no empirical evidence that screening improves decision making. Whether interventions for patients or their caregivers have a clinically significant effect in persons with earlier detected cognitive impairment is still unclear. PRIMARY FUNDING SOURCE Agency for Healthcare Research and Quality.


Archive | 2013

Screening for Cognitive Impairment in Older Adults: An Evidence Update for the U.S. Preventive Services Task Force

Jennifer S Lin; Elizabeth O'Connor; Rebecca C Rossom; Leslie A Perdue; Brittany U Burda; Matthew Thompson; Elizabeth Eckstrom


Archive | 2016

Screening for Depression in Adults

Elizabeth O'Connor; Rebecca C Rossom; Michelle Henninger; Holly C. Groom; Brittany U Burda; Jillian T Henderson; Keshia D Bigler; Evelyn P Whitlock


Archive | 2016

Screening Accuracy of the PHQ and GDS

Elizabeth O'Connor; Rebecca C Rossom; Michelle Henninger; Holly C. Groom; Brittany U Burda; Jillian T Henderson; Keshia D Bigler; Evelyn P Whitlock


Archive | 2016

Table 4, Recommendations of Other Organizations for Depression Screening in Adults

Elizabeth O'Connor; Rebecca C Rossom; Michelle Henninger; Holly C. Groom; Brittany U Burda; Jillian T Henderson; Keshia D Bigler; Evelyn P Whitlock


Archive | 2016

Benefits of Depression Treatment in General and Older Adults With Screen-Detected Depression

Elizabeth O'Connor; Rebecca C Rossom; Michelle Henninger; Holly C. Groom; Brittany U Burda; Jillian T Henderson; Keshia D Bigler; Evelyn P Whitlock


Archive | 2016

FDA Antidepressant Drug Labels for Pregnant and Postpartum Women

Elizabeth O'Connor; Rebecca C Rossom; Michelle Henninger; Holly C. Groom; Brittany U Burda; Jillian T Henderson; Keshia D Bigler; Evelyn P Whitlock


Archive | 2013

Table 2, Summary Table: Screening for Dementia (Dementia vs. MCI/Normal), Very Brief Instruments (Key Question 2)

Jennifer S Lin; Elizabeth O'Connor; Rebecca C Rossom; Leslie A Perdue; Brittany U Burda; Matthew Thompson; Elizabeth Eckstrom


Archive | 2013

Study, Population, and Intervention Characteristics for Key Questions 4 and 5

Jennifer S Lin; Elizabeth O'Connor; Rebecca C Rossom; Leslie A Perdue; Brittany U Burda; Matthew Thompson; Elizabeth Eckstrom


Archive | 2013

Figure 11, Meta-Analyses for AChEIs and Memantine on Serious Adverse Events (Key Question 5)

Jennifer Lin; Elizabeth O'Connor; Rebecca C Rossom; Leslie A Perdue; Brittany U Burda; Matthew Thompson; Elizabeth Eckstrom

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Evelyn P Whitlock

Group Health Research Institute

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Jillian T Henderson

Group Health Research Institute

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