Rejane Santana de Oliveira

Magnitude, geographic distribution and trends of anemia in preschoolers, Brazil

OBJECTIVE To assess the magnitude, geographical distribution and trends of the prevalence of nutritional anemia among preschoolers and to identify risk groups in the state of Paraiba, Brazil. METHODS A cross-sectional survey with multistage random sampling procedure was conducted in 8 urban municipalities of three mid-regions (Zona da Mata, Agreste and Sertão) in the state of Paraíba in 1992. A total of 1,287 preschoolers of both sexes were selected. Hemoglobin was determined by the cyanometahemoglobin method in venous blood, employing <11 g/dl as the cut-off for anemia. Statistical analysis of proportions employed the chi Square test, whereas for means Mann-Whitney and Kruskal-Wallis were the choice, all with confidence interval of 95%. RESULTS The prevalence of anemia was 36.4% (CI 33.7 - 39.1) in the state of Paraiba, greater (p=0.00) than that observed (19.3%, CI 17.3 - 21.5) in 1982. Only 1.0% (CI 0.61 - 1.8) and 6.8% (CI 5.5 - 8.3) of anemia cases were classified as severe and moderate, respectively. Boys presented lower mean hemoglobin concentration (p=0.00), and children under age 3 comprised the biological group of highest susceptibility for deficiency status (p= 0.00). It was found that the second year of life is the most critical for developing nutritional deficiency (p= 0.00). The Agreste mid-region revealed to be the geographical area of highest risk (p= 0.00), outlining a new epidemiological dynamics when compared to the year 1982, when the drought-ridden Sertão region were the geographical area at greatest risk of deficiency. CONCLUSIONS According to international epidemiological criteria, anemia in the studied regions represents a public health problem of moderate degree Assuming the analytical comparability of the 1982 and 1992 cross-sectional surveys, it suggests an increasingly prevalence of nutritional anemia (+88.5%) in all 3 mid-regions in a 10-year-period (1982-92).

Hipovitaminose A em pré-escolares de creches públicas do Recife: indicadores bioquímico e dietético

OBJECTIVE: To evaluate the extent of vitamin A deficiency among preschool children attending public day care centres in Recife, State of Pernambuco, Brazil. METHODS: A cross-sectional survey involving 311 under 5-year-old children of both sexes, randomly selected, and assessed by biochemical (serum retinol), dietetic (vitamin A rich-food consumption) and anthropometric indicators (weight-for-height, weight-for-age and height-for-age). RESULTS: The prevalence of hyporetinolemia (serum retinol 0.05). Vitamin A rich-food intake showed low sensitivity (43.0%) and a very low positive predictive value (6.8%) as a screening diagnostic test for vitamin A deficiency. CONCLUSION: The identification of vulnerable population groups, and the selection of reliable indicators for the assessment of vitamin A status, are both essential for the diagnosis and planning aimed at preventing and controlling vitamin A deficiency.

Nutritional assessment of iron status and anemia in children under 5 years old at public daycare centers.

OBJECTIVES To assess nutritional iron status and anemia prevalence in children less than 5 years old at public daycare centers in the city of Recife, PE, Brazil. METHODS A cross-sectional study, with a systematic random sampling of 162 children aged 6 to 59 months. Nutritional iron status was assessed in terms of body iron reserves (serum ferritin), transferrinemia (serum iron, total iron binding capacity, and transferrin saturation %), erythropoiesis (free erythrocyte protoporphyrin) and hemoglobin production (hemoglobin). RESULTS The prevalence of anemia (hemoglobin < 11.0 g/dL) was 55.6% (95%CI 47.3-63.5), evidence was found of depleted iron stocks (serum ferritin < 12.0 ng/mL) in 30.8% (95%CI 22.9-39.3), low transferrinemia levels (transferrin saturation % < 16) in 60.1% (95%CI 51.7-68.0) and deficient erythropoiesis (free erythrocyte protoporphyrin > 40 micromol/mol heme) in 69.6% (95%CI 61.0-77.1) of the children. Iron parameters were not correlated with sex (p > 0.05). However, children < 24 months exhibited lower hemoglobin concentrations (p < 0.00) and higher levels of free erythrocyte protoporphyrin (p < 0.000) and total iron binding capacity (p < 0.001) when compared with children > 24 months. The significant correlation observed between reserves, transferrinemia and erythropoiesis is a finding that is compatible with the expected lifecycle of iron in the body. CONCLUSIONS Iron deficiency and anemia appear to be an important public health problem among children less than 5 years old at public daycare centers in Recife. Therefore, effective actions aimed at the prevention and control of this deficiency are strongly recommended in this ecological context.

Avaliação do estado nutricional de ferro e anemia em crianças menores de 5 anos de creches públicas

OBJECTIVE: To assess nutritional iron status and anemia prevalence in children less than 5 years old at public daycare centers in the city of Recife, PE, Brazil. METHODS: A cross-sectional study, with a systematic random sampling of 162 children aged 6 to 59 months. Nutritional iron status was assessed in terms of body iron reserves (serum ferritin), transferrinemia (serum iron, total iron binding capacity, and transferrin saturation %), erythropoiesis (free erythrocyte protoporphyrin) and hemoglobin production (hemoglobin). RESULTS: The prevalence of anemia (hemoglobin 40 µmol/mol heme) in 69.6% (95%CI 61.0-77.1) of the children. Iron parameters were not correlated with sex (p > 0.05). However, children 24 months. The significant correlation observed between reserves, transferrinemia and erythropoiesis is a finding that is compatible with the expected lifecycle of iron in the body. CONCLUSIONS: Iron deficiency and anemia appear to be an important public health problem among children less than 5 years old at public daycare centers in Recife. Therefore, effective actions aimed at the prevention and control of this deficiency are strongly recommended in this ecological context.

Parameters of evaluation of zinc nutritional status: comparison between zinc hair rates and serum alkaline phosphatase in pre-scholars of the Municipality of João Pessoa, Paraíba

OBJETIVOS: avaliar o estado nutricional de zinco em criancas de dois a cinco de idade, institucionalizadas em creches do municipio de Joao Pessoa, Paraiba. METODOS: Utilizou-se uma amostra aleatoria sistematica, constituida de 377 criancas. O status nutricional de zinco foi avaliado pelos seguintes parâmetros: concentracoes do mineral no cabelo e niveis de atividade enzimatica da fosfatase alcalina serica. RESULTADOS: a prevalencia das concentracoes inadequadas de zinco no cabelo foi de 61,9% predominando a deficiencia na sua forma grave, 38,5%. A prevalencia das concentracoes inadequadas de niveis de atividade enzimatica da fosfatase alcalina serica foi de 40,1%. As concentracoes de zinco no cabelo nao mostraram correlacao com a fosfatase alcalina serica (r = 0,01; p = 0,882). A distribuicao do zinco no cabelo segundo sexo e idade foi homogenea; comportamento identico foi observado com a fosfatase alcalina. CONCLUSOES: a deficiencia de zinco mostrou-se extremamente elevada no municipio de Joao Pessoa.

Relationship between hemoglobin, serum retinol and habitual meat consumption in the elderly: a population-based study.

Considering the scarcity of data on the relationship between hemoglobin, serum retinol and habitual meat consumption in the elderly, a cross-sectional population-based study was performed, which was representative of the population of a state capital in Northeastern Brazil, including 176 elderly aged between 60 and 90 years, who responded to questionnaires about habitual food consumption and socioeconomic aspects. Blood counts and serum retinol analyses were carried out. The prevalence of anemia was 9.58%, and 96% of elderly showing adequate serum retinol levels. The consumption of vitamin A and iron was adequate in 93.75% and 85%, respectively. There was no correlation between serum retinol and hemoglobin values (p=0.56), and as expected, there was a positive association between meat consumption and hemoglobin (p=0.02). Based on results obtained in this study, it was concluded that the maintenance of adequate vitamin A and meat intake in this population should be encouraged, which appears to be an effective intervention strategy to achieve appropriate serum retinol and hemoglobin values, and hence lower iron deficiency anemia rates.