Renata da Costa Santos

Activity of systemic lupus erythematosus in end-stage renal disease patients: study in a Brazilian cohort.

Background: Dialysis has been associated with lupus remission. We studied the prevalence of systemic lupus erythematosus (SLE) as a cause of end-stage renal disease (ESRD) in the metropolitan area of Rio de Janeiro and assessed disease activity in SLE patients on dialysis. Methods: Of 3,535 ESRD patients, 63 had SLE (1.8%). Fifty-seven entered the study (54 females, 3 males, 38 ± 10 years). Hemodialysis consisted of 3 sessions per week of about 4 h duration, blood flow of about 400 ml/min, bicarbonate dialysate ([Ca2+] = 2.5–3.5 mEq/l) at 500 ml/min and cellulose acetate or polysulfone dialyzers. Activity was initially defined as: non-renal (nr) SLE disease activity index (SLEDAI) of >0; use of at least 20 mg/day of prednisone; and/or any dose of another activity-controlling drug. Fifty-seven ESRD patients without SLE were used as controls. Results:Eighteen SLE patients were under drug treatment; of the remaining, 30 had an nrSLEDAI of >0 totaling 48 patients (84%) initially labeled as active. An apparent activity was also present in 21 controls (37%). Of those, 19 had an nrSLEDAI of <4. With a cutoff of ≧4, figures in each group would be 49 and 4%. Under this criterion, age was the only significant predictor of flare in our SLE ESRD population in a multivariate logistic regression model. Activity remained high in patients who were on dialysis for >5 years (7/18, 39%). Conclusion: SLE accounted for 1.8% of our ESRD patients. Application of SLEDAI to dialysis patients may require consideration of confounding factors related to the ESRD state. Even with a score of ≧4 as a cutoff, SLE activity in dialysis patients was high (49%) and long-lasting. Age was the major determinant of flare.

Impacto da visita domiciliar na capacidade funcional de pacientes com úlceras venosas

OBJECTIVE to assess the impact of protocol home visits on the functional capacity of adult and elderly patients with venous ulcers, before and after guidance received at home. METHOD clinical experimental, randomized, nonblinded and controlled study, developed with 32 patients (case and control groups). Fields of research were the Wound Outpatient Care Unit of the Antônio Pedro University Hospital and households of patients treated in the outpatient unit. Data collection occurred from February to June 2014, by means of an assessment tool of the health care unit, the TINETTI index and a script for directions to be provided to study participants who received home visits. RESULTS participants in the case group showed significant and differentiated improvement post-intervention when compared to the control group, which remained stable. CONCLUSION directions provided in the home context were beneficial to the members of the case group.

Repercusión de la visita domiciliaria en la capacidad funcional de pacientes con úlceras venosas

OBJECTIVE to assess the impact of protocol home visits on the functional capacity of adult and elderly patients with venous ulcers, before and after guidance received at home. METHOD clinical experimental, randomized, nonblinded and controlled study, developed with 32 patients (case and control groups). Fields of research were the Wound Outpatient Care Unit of the Antônio Pedro University Hospital and households of patients treated in the outpatient unit. Data collection occurred from February to June 2014, by means of an assessment tool of the health care unit, the TINETTI index and a script for directions to be provided to study participants who received home visits. RESULTS participants in the case group showed significant and differentiated improvement post-intervention when compared to the control group, which remained stable. CONCLUSION directions provided in the home context were beneficial to the members of the case group.

Evaluation of functional capacity of patients with venous ulcers: a transversal study

The loss of functional capacity in adult and senior patients as a result of venous ulcers harms daily basic activities in general. Aims: To evaluate the functional capacity in caring for adult and senior patients with venous ulcers; to identify the impact of functional limitations in caring for adult and senior patients with venous ulcers; to discuss the relationship of functional capacity and quality of life of adult and senior patients with venous ulcers. Hence, the need to improve the quality of life of such patients emerges, based on the prevention of complications and new treatments. Method: This is a transversal study which has adopted an observational approach.

Consultants for the American Journal of Nephrology 2005

Sandra Garber Cybele Ghossein Richard Glassock Alan Go Laurence Greenbaum Karen Griffi n S. Grigoryev Krishnamurthy Gudehithlu Peter Hart Koichi Hayashi Peter Heering Susan Hou John Hoyer Randall Hudson Todd Ing Eunice John Richard Johnson Michelle Josephson Pradeep Kadambi Ramesh Khanna Orly Kohn Jeff Kopp Mark Kraus Jerome Lane Craig Langman James Lash David Leehey Oliver Lenz Edgar Lerma Jerrold Levine Wilfred Lieberthal Stuart Linas Jill Lindberg Natalia Litbarg Gerard London Rodger Loutzenhiser Friedrich Luft K. Matsumoto Peter McCullough Patrick Murray Naoyuki Nakao Kevin Abbott Rajiv Agarwal Sharon Anderson Gema Ariceta John Asplin Simon Atkinson Asad Bakir George Bakris Vinod Bansal Amelia Bartholomew Amy Barton Pai Daniel Batlle Vecihi Batuman Enrico Benedetti Angelito Bernardo Anil Bidani Peter Blake Anthony Bleyer W. Kline Bolton Michael Braun Carolyn Brecklin Harold Bregman Ellen Brooks Vito Campese Sule Cataltepe Nina Clark Jay Cohn Richard Cohn Judith Cook Andrey Cybulsky Mohamed Daha Farhard Danesh Janice Douglas George Dunea Lance Dworkin Beatrice Edwards Leon Ferder Steven Fishbane Kenneth Fisher Mary Foster Barry Freedman