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Renato Canevotti

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Publication

Featured researches published by Renato Canevotti.

Bioorganic & Medicinal Chemistry Letters | 1997

Design and synthesis of conformationally constrained arginal thrombin inhibitors

Aldo Salimbeni; Fabio Paleari; Renato Canevotti; Marco Criscuoli; Annalisa Lippi; Mauro Angiolini; Laura Belvisi; Carlo Scolastico; Lino Colombo

A series of conformationally constrained arginal thrombin inhibitors was prepared starting from 5,6 or 5,7 bicyclic lactamic structures, that an indirect approach of X-ray structure-based drug design indicated as D-Phe-Pro dipeptide mimetics. The tetrahydroquinolyl sulfonamido derivative Ig (LR-D/009) displayed the best inhibitory potency (IC50 = 0.018 μm), with good selectivity over plasmin and trypsin.

Journal of Medicinal Chemistry | 1995

N-3-Substituted Pyrimidinones as Potent, Orally Active, AT1 Selective Angiotensin II Receptor Antagonists

Aldo Salimbeni; Renato Canevotti; Paleari F; Poma D; Caliari S; Fici F; Cirillo R; Anna Renzetti; Subissi A; Laura Belvisi

Journal of Medicinal Chemistry | 1994

Nonpeptide angiotensin II receptor antagonists. Synthesis, in vitro activity, and molecular modeling studies of N-[(heterobiaryl)methyl] imidazoles.

Aldo Salimbeni; Renato Canevotti; Fabio Paleari; Fabrizio Bonaccorsi; Anna Renzetti; Laura Belvisi; Gianpaolo Bravi; Carlo Scolastico

Archive | 1993

Imidazole ethers having a II antagonist activity

Aldo Salimbeni; Renato Canevotti; Jacques Mizrahi; Carlo Scolastico

Archive | 1997

N-3 substituted pyrimidin-4-ones with AII antagonistic activity

Aldo Salimbeni; Davide Poma; Renato Canevotti

Archive | 1998

Procedimiento para la preparcion de compuestos de 4-bromometil-bifenilo.

Aldo Salimbeni; Renato Canevotti

Archive | 1998

Verfahren zur herstellung von 4-bromomethyl diphenyl verbindungen

Aldo Salimbeni; Renato Canevotti

Archive | 1998

Procede pour la preparation de composes de 4-bromomethyle diphenyle

Renato Canevotti; Aldo Salimbeni

Archive | 1998

Process for preparcion compounds 4-bromomethyl-biphenyl.

Aldo Salimbeni; Renato Canevotti

Archive | 1998

Verfahren zur herstellung von 4-bromomethyl diphenyl verbindungen A process for the preparation of 4-bromomethyl diphenyl compounds

Aldo Salimbeni; Renato Canevotti

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Collaboration

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Carlo Scolastico

University of Milan

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Laura Belvisi

University of Milan

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Lino Colombo

University of Pavia

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Mauro Angiolini

University of Milan

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Gianpaolo Bravi

National Research Council

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