Rhyne Flowers
University of Mississippi Medical Center
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Publication
Featured researches published by Rhyne Flowers.
Acta Cytologica | 2006
Israh Akhtar; Rhyne Flowers; Anwer Siddiqi; Ken Heard; Mithra Baliga
OBJECTIVE To evaluate the diagnostic value of image-guided fine needle aspiration biopsy (FNAB) in the diagnosis and management of vertebral and paravertebral lesions and to review similar studies in the literature. STUDY DESIGN One hundred twenty-four FNAB cases (113 [corrected] patients) of vertebral and paravertebral lesions occurring over a 10-year period were retrieved from the archives of the University of Mississippi Medical Center for review and clinico-radiologic correlation. Thirty-four of the cases included a concurrent core needle biopsy sample, 15 cases had subsequent surgical specimens, while 32 cases had previously established malignancy. The age range was 11 days to 91 years (mean, 46 years), with 57 male patients and 56 female. RESULTS One hundred five cases were vertebral lesions, and 19 cases were paravertebral lesions. FNAB diagnosis were malignant in 33.87% of cases, benign in 5.64%, suspicious in 4.03%, infectious/inflammatory and degenerative in 12.91%, unsatisfactory in 16.13% and negative in 27.42%. The overall sensitivity of the procedure was 89.3% and the specificity, 93.8%. The positive predictive value was 95.7% and negative predictive value, 85.2%. CONCLUSION FNAB is an effective means of establishing a definitive diagnosis of vertebral and paravertebral lesions, allowing appropriate patient management. Cell blocks, core biopsies and ancillary studies are useful adjuncts in rendering the diagnosis.
Diagnostic Cytopathology | 2009
Israh Akhtar; Cristina Luminita Ispas; Rhyne Flowers; Anwer Siddiqi; LaFarra Young; Kimberly A. Donnellan; Ken Heard; Mithra Baliga
Ductopapillary apocrine carcinoma (DPAC) of the eyelid is a rare malignant neoplasm in the periocular region. The relative rarity of this tumor is a diagnostic challenge to the cytopathologist, especially when present as a metastatic lesion to an intraparotid lymph node, where the differential diagnosis includes primary parotid neoplasms, as well as various other metastatic malignancies. There are only a few reported cases of recurrent and metastatic DPAC of the eyelid, and to our knowledge, metastatic DPAC diagnosed by fine‐needle aspiration biopsy (FNAB) has not been described. We report a case of a 65‐year‐old African‐American male with a history of ductopapillary apocrine adenocarcinoma of the eyelid, diagnosed 6 weeks ago now presenting with a recurrence in the same area. Magnetic resonance imaging of the head and neck revealed an intraparotid mass also. FNAB of the parotid mass showed a well‐differentiated papillary adenocarcinoma with a cystic component, similar to a previously excised ductopapillary apocrine adenocarcinoma of the eyelid. Diagn. Cytopathol. 2009.
Diagnostic Cytopathology | 2016
Anas Bernieh; Kristen V. Adams; Xuehui Susan Liu; Rhyne Flowers; Veena Shenoy; Mithra Baliga; Israh Akhtar
The fibrolamellar variant of hepatocellular carcinoma (FL‐HCC) is distinguished from other hepatocellular carcinomas (HCC) by its unique clinical and pathological features. Cytological features of this tumor on fine needle aspiration have been described earlier. We report a rare case of a 17‐year‐old African American male with metastatic FL‐HCC, diagnosed by body fluid cytology. The patient presented with ascites and computed tomography (CT) scan revealed multiple omental masses and liver lesions. The fluid sample was obtained along with the omental biopsy and was found positive for metastatic fibrolamellar hepatocellular carcinoma. The fluid cytology showed atypical polygonal cells with enlarged nuclei, prominent nucleoli, and abundant granular cytoplasm. Cytomorphologic features of FL‐HCC presenting in body fluids have been rarely described before. This case enriches the cytopathology literature by providing awareness of this tumor presenting as metastasis in body fluids, especially in young individuals with liver lesions. Presence of a concurrent biopsy specimen provided cytohistological correlation, as it remains the gold standard for the accuracy and reliability of cytological diagnoses. Diagn. Cytopathol. 2016;44:757–760.
Diagnostic Cytopathology | 2007
Mithra Baliga; Rhyne Flowers; Ken Heard; Anwer Siddiqi; Israh Akhtar
Journal of the American Society of Cytopathology | 2013
Israh Akhtar; Xuehui Liu; Ric Bowlin; Rhyne Flowers; Mithra Baliga
American Journal of Clinical Pathology | 2013
Xuehui Liu; Israh Akhtar; Rhyne Flowers; Mithra Baliga
American Journal of Clinical Pathology | 2013
Xuehui Liu; Veena Shenoy; Rhyne Flowers; Mithra Baliga; Israh Akhtar
Journal of the American Society of Cytopathology | 2012
Israh Akhtar; Rhonda Alexander; Jeffrey Hansen; Ken Gallagher; Anwer Siddiqi; Rhyne Flowers; Jack R. Lewin; Mithra Baliga
Chest | 2009
Ketan C. Patel; Rhyne Flowers; Rajesh Bhagat
Archive | 2006
Syed Zahid Ali; Israh Akhtar; Rhyne Flowers; Anwer Siddiqi; Ken Heard; Mithra Baliga; José A. Jiménez-Heffernan; Blanca Vicandi; Pilar López-Ferrer; Pilar González-Peramato; Ana Pérez-Campos; José M. Viguer