Richard A. Mountford
Bristol Royal Infirmary
Network
Latest external collaboration on country level. Dive into details by clicking on the dots.
Publication
Featured researches published by Richard A. Mountford.
Glycoconjugate Journal | 1993
Anthony P. Corfield; Susan A. Wagner; Luke J.D. O'Donnell; Paul Durdey; Richard A. Mountford; John R. Clamp
Sialidase activity in normal faecal extracts showed a preference for mucin-related glycoprotein and oligosaccharide substrates, but the presence of two or moreO-acetyl esters at positions C7–C9 on the sialic acids retarded the rate of hydrolysis. A specific sialateO-acetyl esterase was detected with a lower total activity relative to sialidase with mucin substrates and having a pH optimum of 7.8 and aKM of approximately 1mm sialateO-acetyl ester. A specific glycosulfatase activity was found in faecal extracts using the substrate lactit-[3H]ol 6-O-sulfate with a pH optimum of pH 5.0 and aKM of approximately 1mm.Faecal extracts from ulcerative colitis (UC) patients had higher sialateO-acetyl esterase and glycosulfatase activity, while mucin sialidase activity was unchanged.Metabolically labelled mucin isolated from UC patients contained less sulfate and had lower sialic acidO-acetylation compared with normal mucin. Colonic mucin was degraded more efficiently by faecal extracts from UC patients compared with normal extracts. The UC mucin was degraded more rapidly than the normal mucin by faecal enzyme extracts from both normal and UC subjects.
Helicobacter | 1997
Lindsay F. Potts; Stephen Lewis; Richard A. Mountford
The mode of transmission of Helicobacter pylori is unclear, but it has been shown that gastroenterologists are at a greater risk of acquiring the infection when performing endoscopy. The current study was designed to assess the risk H. pylori infection in respiratory physicians performing bronchoscopy compared to an at‐risk group of gastroenterologists. We were interested in identifying whether the oral cavity is important in the transmission of H. pylori.
Gastroenterology | 1992
Kw Heaton; Luke J.D. O'Donnell; Fiona E.M. Braddon; Richard A. Mountford; Anthony O. Hughes; Peter J. Cripps
Cancer Research | 1989
Christos Paraskeva; S. Finerty; Richard A. Mountford; Susan C. Powell
Age and Ageing | 1999
Stephen Lewis; Lindsay Potts; Raman Malhotra; Richard A. Mountford
Age and Ageing | 1993
A. F. Safe; B. Warren; A. Corfield; Cliodna McNulty; B. Watson; Richard A. Mountford; A. Read
Clinical Science | 1988
Anthony P. Corfield; Andrew J.K. Williams; John R. Clamp; Susan A. Wagner; Richard A. Mountford
Clinical Science | 1993
J.F.G. Vliegenthart; Anthony P. Corfield; Susan A. Wagner; A. Safe; Richard A. Mountford; John R. Clamp; J.P. Kamerling; Roland Schauer
International Journal of Cancer | 1992
Ann C. Williams; Sara J. Harper; Christopher J. Marshall; Robert W. Gill; Richard A. Mountford; Christos Paraskeva
Age and Ageing | 1993
A. F. Safe; B. Warren; A. Corfield; Cliodna McNulty; B. Watson; Richard A. Mountford; A. Read