Richard H. Adler

Treatment of malignant pleural effusion: a method using tube thoracostomy and talc.

Our experience with a simple bedside method for controlling recurrent symptomatic malignant pleural effusion is presented. The method consists of intercostal tube thoracostomy, instillation of a suspension of talc, and waterseal suction drainage. Based on our experience, we believe certain criteria should be met before undertaking talc pleurodesis. In properly selected patients the results with tube thoracostomy and talc pleurodesis have been uniformly good in preventing fluid recurrence and return of disabling symptoms. The technique and results are discussed.

Collis gastroplasty: Origin and evolution

In 1957 J. Leigh Collis published his innovative operation for treating the difficult problem of the irreducible hiatal hernia, esophagitis, and stricture. The design of the operation was based on the relatively primitive understanding of hiatal hernia and the newly emerging concept of reflux esophagitis. A variety of antireflux operations by different surgeons emerged over the years to follow. The original Collis gastroplasty has been subsequently modified with the addition of both partial and complete fundoplication procedures. The place of the modified Collis gastroplasty-fundoplication operations in todays approach to the problems of hiatal hernia and gastroesophageal reflux disease remains unsettled.

TISSUE CULTURE STUDIES OF CILIATED RESPIRATORY EPITHELIUM.

Abstract Several methods are described for obtaining and growing ciliated respiratory epithelium in tissue culture. The addition of specific antigens to mucosa obtained from allergic patients and sensitized animals did not cause any detectable alterations in the frequency or coordination of the ciliary beat. Patients with chronic bronchitis and intrinsic (nonallergic) bronchial asthma generally had poor ciliary activity.