Richard J. Golinko

Balloon angioplasty for aortic recoarctation: Results of Valvuloplasty and Angioplasty of Congenital Anomalies Registry

Balloon angioplasty was performed in 200 patients with recoarctation of the aorta in a multicenter prospective study. The average age at the time of the procedure was 7.0 years (range 1 month to 26 years). Systolic pressure (mean +/- standard deviation) in the ascending aorta decreased from 134.5 +/- 23.4 to 127.4 +/- 22.0 mm Hg. The descending aortic systolic pressure rose from 92.7 +/- 18.2 to 114.1 +/- 21.6 mm Hg. Peak systolic pressure differences decreased from 41.9 +/- 19.6 to 13.3 +/- 12.1 mm Hg. The diameter of the recurrent coarctation site increased from 5.2 +/- 2.9 to 8.9 +/- 3.4 mm. After angioplasty residual pressure differences of less than or equal to 20 mm Hg were found in 79.4% of the patients. Five patients died of complications related to the procedure (2.5%). Two deaths were directly related to the technical aspects of the procedure and 3 patients died because of the severity of the underlying disease. One additional patient had a cerebrovascular accident. Femoral artery complications occurred in 17 patients (8.5%) and 8 patients required surgical thrombectomy. Balloon angioplasty offers a satisfactory alternative to surgery for recurrent coarctation; both results and complications compare favorably with surgical therapy.

Usefulness of intermittent monitoring of mixed venous oxygen saturation after stage I palliation for hypoplastic left heart syndrome

Most deaths after stage I palliation for hypoplastic left heart syndrome have occurred within the first 24 hours after surgery. Efforts to improve 1-day survival should therefore have significant impact on improving overall survival. Early death has most often been attributed to low cardiac output and abnormalities of pulmonary to systemic flow ratio (Qp/Qs). Thirteen infants underwent stage I palliation and had a catheter inserted in the high superior vena cava (SVC) for intermittent measurement of SVC oxygen saturation. Calculation of Qp/Qs was achieved using SVC saturation as a mixed venous oxygen saturation, and estimating pulmonary venous oxygen saturation. Eleven patients survived, and 2 patients died within the first 24 hours. Abnormalities in Qp/Qs were noted in 12 of 13 patients after operation. In 10 of these 12 patients, there was a high Qp/Qs, which has been associated with poor outcome. High Qp/Qs was noted even in patients with acceptable arterial oxygen saturations (< 85%). SVC saturation increased in all survivors during the first 24 hours, and was associated with a decrease in Qp/Qs. Measurement of SVC oxygen saturation appears to be a valuable adjuvant in the postoperative management of infants after stage I palliation of hypoplastic left heart syndrome. Major abnormalities in Qp/Qs can be detected even with acceptable arterial saturations. With this information, early ventilator/pharmaceutical adjustments can be made which may improve stage I survival.

Initial experience with percutaneous transhepatic cardiac catheterization in infants and children

Percutaneous transhepatic cardiac catheterization is a straightforward procedure that can be performed by experienced pediatric interventionalists with little additional training. We believe that this technique can be a valuable tool in the treatment of selected patients with complex congenital heart defects.

Effect of older age en outcome for stage one palliation of hypoplastic left heart syndrome

Abstract In conclusion, in selected infants, stage 1 palliation for hypoplastic left heart syndrome can be performed at an older age without adversely affecting outcome. This includes patients who previously were awaiting cardiac transplantation. Strategies at improving hemodynamic instability preoperatively, such as manipulating inspired gases and measuring mixed venous oxygen saturations to optimize sol Qp Qs and oxygen delivery, should improve survival after stage 1 palliation even further.

Intracardiac shunting in children with ventricular septal defect: Evaluation with Doppler color flow mapping

In children with a ventricular septal defect, transseptal blood flow has been demonstrated angiographically to be bidirectional in all but the smallest defects. To investigate this phenomenon noninvasively, two-dimensional Doppler color flow echocardiography was used in 77 patients (aged 1 day to 15.5 years, mean 24 months). During isovolumetric contraction, flow was seen from the left to the right ventricle in 82 (98%) of 84 studies. During isovolumetric relaxation, right to left flow was noted in 72 (96%) of 75 studies. During early diastole in patients with an isolated defect, flow was initially from the right to the left ventricle and subsequently reversed to become left to right in 29 (91%) of 32 studies. In patients with concomitant right ventricular volume overload, flow across the ventricular defect was from the right to the left ventricle throughout diastole in 30 (86%) of 35 studies. In each of four patients with d-transposition of the great vessels and each of two patients with 1-transposition of the great vessels, blood flow was from the morphologic left ventricle to the morphologic right ventricle during isovolumetric contraction and from the morphologic right ventricle to the morphologic left ventricle during isovolumetric relaxation. These results demonstrate 1) the complex nature of intracardiac shunting in children with ventricular septal defect as previously shown by angiography; 2) an intrinsic functional difference in the contractile and relaxation properties of the morphologic left and right ventricles; and 3) differences in diastolic blood flow patterns between children with an isolated defect and those with a ventricular septal defect and right ventricular volume overload (p = 0.0001).

Magnetic resonance imaging of isolated abdominal aortic dissection

In the absence of trauma or descending thoracic aortic dissection, abdominal aortic dissection is rare. This report presents a case of isolated abdominal aortic dissection. Magnetic resonance imaging may reliably diagnose and characterize these dissections without the use of contrast material.

Use of Single Lead VDD Pacing in Children

The development of transvenous ventricular pacing leads with proximal electrodes capable of atrial sensing and the recent availability of smaller generators has created the opportunity to treat children with complete AV block and normal sinus node function with a transvenous single lead VDD pacing system. Studies in adults have demonstrated this system to be efficacious with low complication rates. Transvenous single lead VDD pacemakers were implanted in ten children, aged 5–15 years, between December 1993 and April 1996, in our institution. The indications were complete AV block with severe bradycardia in 5 patients, second‐degree or complete A V block following congenital heart surgery in 3, complete A V block with long QT syndrome in 1, and second‐degree AV block and syncope in 1. There were no complications related to the procedure in any case. P and R wave amplitudes were measured and thresholds were determined intraoperatively on all patients. Amplitudes and thresholds were remeasured on seven patients with a mean follow‐up of 17 months; Holter monitors were performed on seven patients with a mean follow‐up of 16 months. P and H wave amplitudes were generally diminished at follow‐up compared to initial values but remained within an acceptable range for all patients. Four patients required reprogramming after pacemaker insertion, 1 received an atrial lead for dual chamber pacing, 1 required repositioning for lead dislodgment. and 1 patient required a new lead for an inadequate ventricular pacing threshold. No patient had evidence of failure to sense or capture as evaluated by Halter monitoring at last follow‐up. Single lead VDD pacing systems can be successfully used in properly selected children with high degree or complete AV block with normal sinus node function.