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Dive into the research topics where Richard J. Harvey is active.

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Featured researches published by Richard J. Harvey.


Laryngoscope | 2012

Endoscopic skull base reconstruction of large dural defects: A Systematic Review of Published Evidence

Richard J. Harvey; Priscilla Parmar; Raymond Sacks; Adam M. Zanation

Systematically review the outcomes of endoscopic endonasal techniques to reconstruct large skull base defects (ESBR). Such surgical innovation is likely to be reported in case series, retrospective cohorts, or case‐control studies rather than higher level evidence.


Otolaryngology-Head and Neck Surgery | 2008

Effects of endoscopic sinus surgery and delivery device on cadaver sinus irrigation

Richard J. Harvey; John C. Goddard; Sarah K. Wise; Rodney J. Schlosser

Objective Assess paranasal sinus distribution of topical solutions following endoscopic sinus surgery (ESS) using various delivery devices. Study Design Experimental prospective study. Subjects and Methods Ten cadaver sinus systems were irrigated with Gastroview before surgery, after ESS, and after medial maxillectomy. Delivery was via pressurized spray (NasaMist), neti pot (NasaFlo), and squeeze bottle (Sinus Rinse). Scans were performed before and after each delivery with a portable CT machine (Xoran xCAT), and blinded assessments were made for distribution to individual sinuses. Results Total sinus distribution was greater post-ESS (P < 0.001). Additional distribution was gained with medial maxillectomy (P = 0.02). Influence of delivery device on distribution was significantly higher with neti pot > squeeze bottle > pressurized spray (P < 0.001). Frontal sinus penetration was greatest after surgery (P = 0.001). Conclusion ESS greatly enhances the delivery of nasal solutions, regardless of delivery device. Pressurized spray solutions in un-operated sinuses provide little more than nasal cavity distribution. Use of squeeze bottle/neti pot post-ESS offers a greatly enhanced ability to deliver solutions to the paranasal sinuses.


Allergy | 2011

Lack of efficacy of long-term, low-dose azithromycin in chronic rhinosinusitis: a randomized controlled trial

W. J. M. Videler; Lydia Badia; Richard J. Harvey; Simon Gane; Christos Georgalas; F. W. van der Meulen; Menger Dj; M. T. Lehtonen; S K Toppila-Salmi; S. I. Vento; M Hytönen; Peter Hellings; Livije Kalogjera; Valerie J. Lund; Glenis K. Scadding; J. Mullol; W. J. Fokkens

To cite this article: Videler WJ, Badia L, Harvey RJ, Gane S, Georgalas C, van der Meulen FW, Menger DJ, Lehtonen MT, Toppila‐Salmi SK, Vento SI, Hytönen M, Hellings PW, Kalogjera L, Lund VJ, Scadding G, Mullol J, Fokkens WJ. Lack of Efficacy of long‐term, low‐dose azithromycin in chronic rhinosinusitis: a randomized controlled trial. Allergy 2011; 66: 1457–1468.


International Forum of Allergy & Rhinology | 2013

Topical therapies in the management of chronic rhinosinusitis: an evidence-based review with recommendations

Luke Rudmik; Monica Hoy; Rodney J. Schlosser; Richard J. Harvey; Kevin C. Welch; Valerie J. Lund; Timothy L. Smith

Topical therapies have become an integral component in the management plan for chronic rhinosinusitis (CRS). Several topical therapy strategies have been evaluated, but a formal comprehensive evaluation of the evidence has never been performed. The purpose of this article is to provide an evidence‐based approach for the utilization of topical therapies in the management of CRS.


Clinical & Experimental Allergy | 2015

Group 2 innate lymphoid cells (ILC2s) are increased in chronic rhinosinusitis with nasal polyps or eosinophilia

Jacqueline Ho; Michelle Bailey; John Zaunders; Nadine Mrad; Ray Sacks; William A. Sewell; Richard J. Harvey

Chronic rhinosinusitis (CRS) is a heterogeneous disease with an uncertain pathogenesis. Group 2 innate lymphoid cells (ILC2s) represent a recently discovered cell population which has been implicated in driving Th2 inflammation in CRS; however, their relationship with clinical disease characteristics has yet to be investigated.


Laryngoscope | 2008

Endoscopic Transnasal Craniotomy and the Resection of Craniopharyngioma

Aldo Cassol Stamm; Eduardo Vellutini; Richard J. Harvey; João Flávio Nogeira; Diego R. Herman

Objectives/Hypothesis: To describe the utility of a large transnasal craniotomy and its reconstruction in the surgical management of patients with craniopharyngioma.


Journal of Neurosurgery | 2009

Closure of large skull base defects after endoscopic transnasal craniotomy. Clinical article.

Richard J. Harvey; João F. Nogueira; Rodney J. Schlosser; Sunil J. Patel; Eduardo Vellutini; Aldo Cassol Stamm

OBJECT The authors describe the utility of and outcomes after endoscopic transnasal craniotomy and skull reconstruction in the management of skull base pathologies. METHODS The authors conducted a observational study of patients undergoing totally endoscopic, transnasal, transdural surgery. The patients included in the study underwent treatment over a 12-month period at 2 tertiary medical centers. The pathological entity, region of the ventral skull base resected, and size of the dural defect were recorded. Approach-related complications were documented, as well as CSF leaks, infections, bleeding-related complications, and any minor complications. RESULTS Thirty consecutive patients were assessed during the study period. The patients had a mean age of 45.5 +/- 20.2 years and a mean follow-up period of 182.4 +/- 97.5 days. The dural defects reconstructed were as large as 5.5 cm (mean 2.49 +/- 1.36 cm). One patient (3.3%) had a CSF leak that was managed endoscopically. Two patients had epistaxis that required further care, but there were no complications related to intracranial infections or bleeding. Some minor sinonasal complications occurred. CONCLUSIONS Skull base endoscopic reconstructive techniques have significantly advanced in the past decade. The use of pedicled mucosal flaps in the reconstruction of large dural defects resulting from an endoscopic transnasal craniotomy permits a robust repair. The CSF leak rate in this study is comparable to that achieved in open approaches. The ability to manage the skull base defects successfully with this approach greatly increases the utility of transnasal endoscopic surgery.


International Forum of Allergy & Rhinology | 2012

Structured histopathology profiling of chronic rhinosinusitis in routine practice

Kornkiat Snidvongs; Matthew Lam; Raymond Sacks; Peter Earls; Larry Kalish; P. Seamus Phillips; Eleanor Pratt; Richard J. Harvey

Tissue eosinophilia in chronic rhinosinusitis (CRS) is a marker of inflammatory disorders recalcitrant to surgical intervention. Eosinophilic chronic rhinosinusitis (ECRS) is traditionally associated with asthma, polyps, aspirin sensitivity, high serum eosinophilia, and elevated immunoglobulin E (IgE). However, patients with ECRS may not present with these associations and there is a need to establish other surrogate markers. The objective of the study was to determine the associations between the histopathology, serology, and clinical characteristics in CRS patients.


International Forum of Allergy & Rhinology | 2016

International Consensus Statement on Allergy and Rhinology: Rhinosinusitis

Richard R. Orlandi; Todd T. Kingdom; Peter H. Hwang; Timothy L. Smith; Jeremiah A. Alt; Fuad M. Baroody; Pete S. Batra; Manuel Bernal-Sprekelsen; Neil Bhattacharyya; Rakesh K. Chandra; Alexander G. Chiu; Martin J. Citardi; Noam A. Cohen; John M. DelGaudio; Martin Desrosiers; Hun Jong Dhong; Richard Douglas; Berrylin J. Ferguson; Wytske J. Fokkens; Christos Georgalas; Andrew Goldberg; Jan Gosepath; Daniel L. Hamilos; Joseph K. Han; Richard J. Harvey; Peter Hellings; Claire Hopkins; Roger Jankowski; Amin R. Javer; Robert C. Kern

Isam Alobid, MD, PhD1, Nithin D. Adappa, MD2, Henry P. Barham, MD3, Thiago Bezerra, MD4, Nadieska Caballero, MD5, Eugene G. Chang, MD6, Gaurav Chawdhary, MD7, Philip Chen, MD8, John P. Dahl, MD, PhD9, Anthony Del Signore, MD10, Carrie Flanagan, MD11, Daniel N. Frank, PhD12, Kai Fruth, MD, PhD13, Anne Getz, MD14, Samuel Greig, MD15, Elisa A. Illing, MD16, David W. Jang, MD17, Yong Gi Jung, MD18, Sammy Khalili, MD, MSc19, Cristobal Langdon, MD20, Kent Lam, MD21, Stella Lee, MD22, Seth Lieberman, MD23, Patricia Loftus, MD24, Luis Macias‐Valle, MD25, R. Peter Manes, MD26, Jill Mazza, MD27, Leandra Mfuna, MD28, David Morrissey, MD29, Sue Jean Mun, MD30, Jonathan B. Overdevest, MD, PhD31, Jayant M. Pinto, MD32, Jain Ravi, MD33, Douglas Reh, MD34, Peta L. Sacks, MD35, Michael H. Saste, MD36, John Schneider, MD, MA37, Ahmad R. Sedaghat, MD, PhD38, Zachary M. Soler, MD39, Neville Teo, MD40, Kota Wada, MD41, Kevin Welch, MD42, Troy D. Woodard, MD43, Alan Workman44, Yi Chen Zhao, MD45, David Zopf, MD46


International Forum of Allergy & Rhinology | 2012

Corticosteroid nasal irrigations after endoscopic sinus surgery in the management of chronic rhinosinusitis

Kornkiat Snidvongs; Eleanor Pratt; David Chin; Raymond Sacks; Peter Earls; Richard J. Harvey

Inflammatory dysfunction is considered an important part of chronic rhinosinusitis (CRS). Corticosteroid therapy has been widely used in CRS. Effective topical delivery has been previously problematic. The post–endoscopic sinus surgery (ESS) corridor is essential for adequate topical drug access. Devices delivering large volume with positive pressure allow better distribution to sinus mucosa. The objective of this study is to evaluate the efficacy of postoperative topical sinonasal steroid irrigations for CRS.

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Raymond Sacks

St. Vincent's Health System

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Rodney J. Schlosser

Medical University of South Carolina

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Henry P. Barham

University of New South Wales

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David Chin

St. Vincent's Health System

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Jenna M. Christensen

University of New South Wales

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Peter Earls

St. Vincent's Health System

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Janet Rimmer

Woolcock Institute of Medical Research

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