Richard P. Elzay

Squamous odontogenic tumor. Report of six cases of a previously undescribed lesion.

Six cases of a previously unnamed oral lesion are described and the name squamous odontogenic tumor is applied. The lesion causes radiolucent areas of bone destruction adjacent to the roots of teeth. In one case there were multiple separate lesions. Light microscopy revealed numerous islands of benign squamous epithelium with focal areas of keratinization and calcification. Electron microscope examination in one case showed normal squamous epithelial cells with abundant glycogen granules, tonofilaments and myelin bodies. Complete surgical excision seems the best therapy, as only one lesion recurred following treatment.

Traumatic ulcerative granuloma with stromal eosinophilia (Riga-Fede's disease and traumatic eosinophilic granuloma)

A review of the English literature revealed ten lesions classified as Riga-Fedes disease and nineteen lesions classified as traumatic eosinophilic granuloma. These two entities have the same histologic features and are often associated with a history of trauma. These are benign, reactive, nonosseous lesions that occur either in infancy or later in life. It is suggested that they be considered as one entity. To delineate them from more aggressive lesions, such as the eosinophilic granuloma of histiocytosis X, the author suggests the term traumatic ulcerative granuloma with stromal eosinophilia. Forty-one previously unreported cases are described. Histologic examination revealed the presence of mast cells in addition to eosinophils. A pathogenesis for traumatic ulcerative granuloma with stromal eosinophilia, based on the hypothesis that mast cells release an eosinophilic chemotactic factor and that eosinophils may act as cytotoxic agents, is suggested.

Tumors of minor salivary glands. A report of 73 cases

Seventy‐three cases of minor salivary gland tumors are presented and discussed. Benign mixed tumor is the most common lesion. This tumor can be treated conservatively. The many histologic variations in benign mixed tumor must be kept in mind for the correct pathologic diagnosis. About 50 percent of all of the minor salivary gland tumors are malignant. The most common of the malignant tumors is adenoid cystic carcinoma. This is also the most lethal of the cancers of minor salivary glands and the most difficult to treat. About 10 percent of the minor salivary gland tumors are low‐grade mucoepidermoid carcinomas. These lesions have a good prognosis and can be treated safely by conservative local excision. The literature on minor salivary gland tumors is reviewed, particularly with regard to treatment and follow‐up. The review substantiates conservative treatment for benign mixed tumor and low‐grade mucoepidermoid carcinomas.

Ultrastructural observations on a gingival granular cell tumor (congenital epulis)

A congenital epulis from a 1‐hour‐old female infant was subjected to ultramicroscopic observations. The lesion was found to be quite similar to the usual granular cell tumors as previously studied. The finding of junctional complexes between some of the granular cells suggested that these cells may be of epithelial origin. This, however, is not entirely conclusive and further avenues for future studies are suggested.

Myxomas of the paraoral--oral soft tissues.

Fifteen cases of soft-tissue myxoma of the paraoral-oral structures have been presented. Eleven cases were garnered from an extensive review of the literature, and four previously unreported cases are described. The myxomas were slow-growing, insidious, infiltrative tumors which occurred in all age groups, with an average patient age of 38 years. Most frequent locations were the cheek, floor of the mouth, and palate. The lesions were present from 2 weeks to 6 years prior to treatment. In this series all the myxomas were treated by surgical excision, with no evidence of recurrences or metastases. The recommended therapy is surgical resection with adequate margins. Other myxomatous lesions which may mimic a myxoma are mentioned.

Local Effect of Alcohol in Combination with DMBA on Hamster Cheek Pouch

SYNOPSIS IN INTERLINGUA LE EFFECTO LOCAL EXERCITE SUPER LE CAVITATE VESTIBULAR DEL HAMSTER PER ALCOHOL IN COMBINATION CON DMBA (7,12-DIMETHYL-BENZ-(a)-ANTHRACENO).—Le cavitates esseva pingite con solutiones de DMBA in oleo mineral, solutiones de DMBA in alcohol ethylic, oleo mineral, e alcohol ethylic durante 9 septimanas e tenite sub observation durante 18. Le periodos latente e le magnitude e numero del resultante tumores esseva registrate. Le constatationes microscopic esseva correlationate subsequentemente con le constatationes clinic. Le cavitates tractate con DMBA in alcohol exhibiva tumores plus precocemente e de magnitude e numero plus grande que cavitates tractate con DMBA in oleo mineral. Alcohol sol non produceva tumores. Per consequente il pare que alcohol age localmente como agente promotori in experimental carcinogenese oral.

Chondroblastoma of the temporomandibular joint arising from articular cartilage: A previously unreported presentation of an uncommon neoplasm

Abstract A 31-year-old woman presented with a mass in the left side of the face which was initially thought to represent a mixed tumor of the parotid gland but was ultimately diagnosed as a chondroblastoma arising from the articular cartilage of the mandibular condyle. The usual chondroblastoma is an intraosseous benign tumor which is generally thought to arise from the cartilaginous epiphysis. This first reported case of a primary articular chondroblastoma indicates that the neoplasm can originate from nonepiphyseal cartilage as well.

Dentinal dysplasia. Report of a case.

Abstract We have described a case of dentinal dysplasia in a 29-year-old woman with ten remaining teeth exhibiting no color change, attrition, or dental caries and radiographically showing dwarfed, constricted roots with calcific masses in the pulp chamber. The family history was not complete, but the patients three children were not affected. We believe that the case of calcified papilla reported by Stafne represents either a less severe manifestation of dental dysplasia or a very closely related malady.

Fibrous defect (nonossifying fibroma) of the mandible

Two cases of fibrous defect (nonossifying fibroma) of the mandible are presented. Each case occurred in the mandibular ramus of an 11-year-old girl. The usual fibrous defect of bone is an intraosseous fibrous, nonneoplastic, reactive lesion which appears as a well-delineated defect in the metaphysis of long bones. This report reviews the literature, histopathology, and classification of the fibrous defect of bone.

Clinical and histologic evaluation of commercially prepared radiopaque denture material

Abstract Four commercial radiopaque denture acrylic resins were evaluated. Clinical, histologic, and radiographic changes were evaluated in 27 edentulous patients. In each patient, one denture was made of a regular acrylic resin denture base material, and the opposing denture was made of a developmental radiopaque denture base material. The results of this study indicate that developmental material B (which contains barium fluoride) was histologically acceptable and that no instances of clinical toxicity were reported. However, five of the test dentures developed a dark stain around the necks of their porcelain teeth. This was not consistent, and the dentures were clinically acceptable in all other respects. Further study is recommended to eliminate this stain reaction.