Richard W. Nyffeler

Experimental Rotator Cuff Repair. A Preliminary Study

BACKGROUND The repair of chronic, massive rotator cuff tears is associated with a high rate of failure. Prospective studies comparing different repair techniques are difficult to design and carry out because of the many factors that influence structural and clinical outcomes. The objective of this study was to develop a suitable animal model for evaluation of the efficacy of different repair techniques for massive rotator cuff tears and to use this model to compare a new repair technique, tested in vitro, with the conventional technique. METHODS We compared two techniques of rotator cuff repair in vivo using the left shoulders of forty-seven sheep. With the conventional technique, simple stitches were used and both suture ends were passed transosseously and tied over the greater tuberosity of the humerus. With the other technique, the modified Mason-Allen stitch was used and both suture ends were passed transosseously and tied over a cortical-bone-augmentation device. This device consisted of a poly(L/D-lactide) plate that was fifteen millimeters long, ten millimeters wide, and two millimeters thick. Number-3 braided polyester suture material was used in all of the experiments. RESULTS In pilot studies (without prevention of full weight-bearing), most repairs failed regardless of the technique that was used. The simple stitch always failed by the suture pulling through the tendon or the bone; the suture material did not break or tear. The modified Mason-Allen stitch failed in only two of seventeen shoulders. In ten shoulders, the suture material failed even though the stitches were intact. Thus, we concluded that the modified Mason-Allen stitch is a more secure method of achieving suture purchase in the tendon. In eight of sixteen shoulders, the nonaugmented double transosseous bone-fixation technique failed by the suture pulling through the bone. The cortical-bone-augmentation technique never failed. In definite studies, prevention of full weight-bearing was achieved by fixation of a ten-centimeter-diameter ball under the hoof of the sheep. This led to healing in eight of ten shoulders repaired with the modified Mason-Allen stitch and cortical-bone augmentation. On histological analysis, both the simple-stitch and the modified Mason-Allen technique caused similar degrees of transient localized tissue damage. Mechanical pullout tests of repairs with the new technique showed a failure strength that was approximately 30 percent of that of an intact infraspinatus tendon at six weeks, 52 percent of that of an intact tendon at three months, and 81 percent of that of an intact tendon at six months. CONCLUSIONS The repair technique with a modified Mason-Allen stitch with number-3 braided polyester suture material and cortical-bone augmentation was superior to the conventional repair technique. Use of the modified Mason-Allen stitch and the cortical-bone-augmentation device transferred the weakest point of the repair to the suture material rather than to the bone or the tendon. Failure to protect the rotator cuff post-operatively was associated with an exceedingly high rate of failure, even if optimum repair technique was used. CLINICAL RELEVANCE Different techniques for rotator cuff repair substantially influence the rate of failure. A modified Mason-Allen stitch does not cause tendon necrosis, and use of this stitch with cortical-bone augmentation yields a repair that is biologically well tolerated and stronger in vivo than a repair with the conventional technique. Unprotected repairs, however, have an exceedingly high rate of failure even if optimum repair technique is used. Postoperative protection from tension overload, such as with an abduction splint, may be necessary for successful healing of massive rotator cuff tears.

Classification of glenohumeral joint instability.

Shoulder instabilities have been classified according to the etiology, the direction of instability, or on combinations thereof. The current authors describe a classification system, which distinguishes between static instabilities, dynamic instabilities, and voluntary dislocation. Static instabilities are defined by the absence of classic symptoms of instability and are associated with rotator cuff or degenerative joint disease. The diagnosis is radiologic, not clinical. Dynamic instabilities are initiated by a trauma and may be associated with capsulolabral lesions, defined glenoid rim lesions, or with hyperlaxity. They may be unidirectional or multidirectional. Voluntary dislocation is classified separately because dislocations do not occur inadvertently but under voluntary control of the patient.

Reverse total shoulder arthroplasty

&NA; The radical changes in prosthetic design made in the mid 1980s transformed the historically poorly performing reverse ball‐and‐socket total shoulder prosthesis into a highly successful salvage implant for pseudoparalytic, severely rotator cuff‐deficient shoulders. Moving the center of rotation more medial and distal as well as implanting a large glenoid hemisphere that articulates with a humeral cup in 155° of valgus are the biomechanical keys to sometimes spectacular short‐ to mid‐term results. Use of the reverse total shoulder arthroplasty device allows salvage of injuries that previously were beyond surgical treatment. However, this technique has a complication rate approximately three times that of conventional arthroplasty. Radiographic and clinical results appear to deteriorate over time. Proper patient selection and attention to technical details are needed to reduce the currently high complication rate.

Measurement of glenoid version: conventional radiographs versus computed tomography scans

Glenoid version seems to play an important role in the stability and loading of the glenohumeral joint. The purpose of this study was to compare measurements of glenoid version on axillary views and computed tomography (CT) scans. Radiographs and CT scans of 25 patients evaluated predominantly for glenohumeral joint instability and 25 patients after implantation of a total shoulder prosthesis were analyzed by 3 independent observers. In all patients glenoid version was determined on an axillary view and on a CT scan at the mid-glenoid level. The mean glenoid version measured on CT scans was 3 degrees of retroversion in the instability group (range, 7 degrees of anteversion to 16 degrees of retroversion) and 2 degrees of anteversion in the total shoulder prosthesis group (range, 16 degrees of anteversion to 23 degrees of retroversion). Glenoid retroversion was overestimated on plain radiographs in 86%. The mean difference between measurements of glenoid version on axillary views and CT cuts was 6.5 degrees (range, 0 degrees -21 degrees ), and the coefficient of correlation between these measurements was 0.33 in the instability group and 0.67 in the prosthesis group. In conclusion, glenoid version cannot be determined accurately on standard axillary radiographs, either preoperatively or postoperatively. Studies that assess the role of glenoid component orientation should use a reproducible method of assessment such as CT.

Analysis of a retrieved Delta III total shoulder prosthesis

A reversed Delta III total shoulder prosthesis was retrieved post-mortem, eight months after implantation. A significant notch was evident at the inferior pole of the scapular neck which extended beyond the inferior fixation screw. This bone loss was associated with a corresponding, erosive defect of the polyethylene cup. Histological examination revealed a chronic foreign-body reaction in the joint capsule. There were, however, no histological signs of loosening of the glenoid base plate and the stability of the prosthetic articulation was only slightly reduced by the eroded rim of the cup.

Posterior glenoid rim deficiency in recurrent (atraumatic) posterior shoulder instability

Abstract Objective. To assess the shape of the posterior glenoid rim in patients with recurrent (atraumatic) posterior instability. Design and patients.CT examinations of 15 shoulders with recurrent (atraumatic) posterior instability were reviewed in masked fashion with regard to abnormalities of the glenoid shape, specifically of its posterior rim. The glenoid version was also assessed. The findings were compared with the findings in 15 shoulders with recurrent anterior shoulder instability and 15 shoulders without instability. For all patients, surgical correlation was available. Results.Fourteen of the 15 (93%) shoulders with recurrent (atraumatic) posterior shoulder instability had a deficiency of the posteroinferior glenoid rim. In patients with recurrent anterior instability or stable shoulders such deficiencies were less common (60% and 73%, respectively). The craniocaudal length of the deficiencies was largest in patients with posterior instability. When a posteroinferior deficiency with a craniocaudal length of 12 mm or more was defined as abnormal, sensitivity and specificity for diagnosing recurrent (atraumatic) posterior instability were 86.7% and 83.3%, respectively. There was a statistically significant difference in glenoid version between shoulders with posterior instability and stable shoulders (P=0.01). Conclusion.Recurrent (atraumatic) posterior shoulder instability should be considered in patients with a bony deficiency of the posteroinferior glenoid rim with a craniocaudal length of more than 12 mm.

Radiographic and Computed Tomography Analysis of Cemented Pegged Polyethylene Glenoid Components in Total Shoulder Replacement

BACKGROUND Glenoid loosening continues to be the primary reason for failure of total shoulder arthroplasty. The purpose of this study was to evaluate, with use of a sensitive and reproducible imaging method, the radiographic and clinical results of total shoulder replacement with a pegged, cemented polyethylene glenoid implant. METHODS Forty-three patients (forty-seven shoulders) underwent a total shoulder replacement with a cemented polyethylene glenoid component with four threaded pegs. The patients were examined clinically, with fluoroscopically guided radiographs, and with computed tomography at an average of forty months. In addition to conventional scoring of radiographic lucency, an 18-point scoring system was used to quantify cement-peg lucencies in six zones of the back surface of the glenoid component as seen on computed tomography scans. RESULTS On the average, the absolute Constant score improved from 39 points preoperatively to 70 points at the time of follow-up (p = 0.0001) and the pain score improved from 5 to 13 points (p = 0.001). The mean active anterior elevation improved by 34 degrees (p = 0.001) and the mean abduction, by 46 degrees (p = 0.006). Two patients had symptomatic glenoid loosening requiring revision. Twenty-one of the forty-seven shoulders had radiographic lucency around the glenoid pegs, and nine had progression of the lucency by at least two grades. Computed tomography detected lucencies, primarily at the bone-cement interface, in thirty-six shoulders. The scores for the lucencies seen on the computed tomography scans were associated with the radiographic lucency scores (p < 0.001), pain scores (p = 0.04), and abduction strength (p = 0.02). Computed tomography was more sensitive than radiography with regard to identifying the number of pegs associated with lucency and the size of the lucencies. The overall reproducibility of the scoring based on the computed tomography was higher than that of the radiographic scoring. CONCLUSIONS Computed tomography provided a more sensitive and reproducible tool for the assessment of loosening of pegged glenoid components than did fluoroscopically guided conventional radiography. Further improvement in implant design and fixation technique appears to be necessary for long-term success of cemented glenoid components.

Structural changes of the rotator cuff caused by experimental subacromial impingement in the rat

Subacromial impingement of the infraspinatus tendon was experimentally created in 28 young adult rats by thickening the undersurface of the acromion with either one or two platelike bony transplants of the ipsilateral scapular spine. Nine nonoperated and eight shoulders that had undergone a sham operation served as control groups. The rats were killed after 2 days and after 1, 2, 4, 8, 16, and 32 weeks for histologic evaluation. All rats with experimental subacromial impingement showed an infraspinatus tear on the bursal side of the tendon. An isolated tear on the articular side or within the tendon was not seen. Two plates caused larger tears than one (P = .04), and more long-standing impingement was associated with larger lesions (P = .002). Multiple chondrocytes were observed within the tendon adjacent to the bony transplants. No calcium deposits were found. In the subacromial space rapid thickening of the bursa was observed. The undersurfaces of the bony transplants showed no evidence of abrasion or remodeling caused by the tendon. The shoulders of the control groups were found intact without any alteration. Experimental subacromial impingement in the rat caused bursal side rotator cuff tears. The type of partial tears that are most frequently observed in clinical practice, that is, intratendinous and articular side tears, were not seen in this experimental model.

The effect of capsular tightening on humeral head translations.

Idiopathic or surgical tightening of the glenohumeral joint capsule may cause displacement of the humeral head relative to the glenoid fossa and favor the development of instability and/or osteoarthritis.

Influence of peg design and cement mantle thickness on pull-out strength of glenoid component pegs

Fixation of the glenoid component is critical to the outcome of total shoulder arthroplasty. In an in vitro study, we analysed the effect of surface design and thickness of the cement mantle on the pull-out strength of the polyethylene pegs which are considered essential for fixation of cemented glenoid components. The macrostructure and surface of the pegs and the thickness of the cement mantle were studied in human glenoid bone. The lowest pull-out forces, 20 +/- 5 N, were for cylindrical pegs with a smooth surface fixed in the glenoid with a thin cement mantle. The highest values, 425 +/- 7 N, were for threaded pegs fixed with a thicker cement mantle. Increasing the diameter of the hole into which the peg is inserted from 5.2 to 6.2 mm thereby increasing the thickness of the cement mantle, improved the mean pull-out force for the pegs tested.