Rick Sanghera

Head-to-head comparison of arrhythmia discrimination performance of subcutaneous and transvenous ICD arrhythmia detection algorithms: The START study

Arrhythmia Detection with S‐ICD Versus Transvenous ICDs.

A New Algorithm to Reduce Inappropriate Therapy in the S-ICD System

The subcutaneous ICD system (S‐ICD) has been shown to be a safe and effective treatment for patients at risk for sudden cardiac death. This device reliably detects ventricular tachyarrhythmias with a low incidence of inappropriate shocks for supraventricular arrhythmias. However, T‐wave oversensing (TWOS) is more common with the S‐ICD compared with transvenous systems. We developed a novel discrimination algorithm to reduce TWOS without compromising tachyarrhythmia discrimination.

Feasibility of Defibrillation and Automatic Arrhythmia Detection Using an Exclusively Subcutaneous Defibrillator System in Canines

Subcutaneous Defibrillation in Canines. Introduction: This study reports the experimental process leading to development of an automatic totally subcutaneous implantable cardioverter defibrillator (SICD) system engineered for human use.

Development of an Entirely Subcutaneous Implantable Cardioverter-Defibrillator

The recent advent of an entirely subcutaneous implantable defibrillator (ICD) has provided a relevant contribution to the debate concerning the use of ICD therapy in patients at high risk for death. Although conventional transvenous ICDs have proven very effective during the past 23 years, they still appear to be limited by nontrivial acute and long-term complications. This study delineates some of the historical and current issues characterizing the advent of the subcutaneous ICD system in daily clinical practice. Subcutaneous ICDs have proven effective in more than 1100 patients worldwide and appear to be competitive with transvenous ICD in all clinical conditions not requiring antibradycardia, antitachycardia, or cardiac resynchronization pacing.