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Dive into the research topics where Rie Kikkawa is active.

Publication


Featured researches published by Rie Kikkawa.


Journal of Toxicological Sciences | 2006

In vivo hepatotoxicity study of rats in comparison with in vitro hepatotoxicity screening system.

Rie Kikkawa; Masaaki Fujikawa; Toshinori Yamamoto; Yoshimasa Hamada; Hiroshi Yamada; Ikuo Horii


Journal of Toxicological Sciences | 2005

Investigation of a hepatotoxicity screening system in primary cell cultures --"what biomarkers would need to be addressed to estimate toxicity in conventional and new approaches?".

Rie Kikkawa; Toshinori Yamamoto; Tamio Fukushima; Hiroshi Yamada; Ikuo Horii


Journal of Toxicological Sciences | 2006

Investigation of proteomic biomarkers in in vivo hepatotoxicity study of rat liver: toxicity differentiation in hepatotoxicants.

Toshinori Yamamoto; Rie Kikkawa; Hiroshi Yamada; Ikuo Horii


Journal of Toxicological Sciences | 2005

IDENTIFICATION OF OXIDATIVE STRESS-RELATED PROTEINS FOR PREDICTIVE SCREENING OF HEPATOTOXICITY USING A PROTEOMIC APPROACH

Toshinori Yamamoto; Rie Kikkawa; Hiroshi Yamada; Ikuo Horii


Journal of Toxicological Sciences | 2005

EFFECTS OF MALE REPRODUCTIVE TOXICANTS ON GENE EXPRESSION IN RAT TESTES

Tamio Fukushima; Toshinori Yamamoto; Rie Kikkawa; Yoshimasa Hamada; Masatoshi Komiyama; Chisato Mori; Ikuo Horii


Journal of Toxicological Sciences | 2005

Protein expression analysis of rat testes induced testicular toxicity with several reproductive toxicants.

Toshinori Yamamoto; Tamio Fukushima; Rie Kikkawa; Hiroshi Yamada; Ikuo Horii


Journal of Toxicological Sciences | 2006

GENOMIC CLUSTER AND NETWORK ANALYSIS FOR PREDICTIVE SCREENING FOR HEPATOTOXICITY

Tamio Fukushima; Rie Kikkawa; Yoshimasa Hamada; Ikuo Horii


Archive | 2008

Utilization of an in vitro Hepatotoxicity Test in the Early Stage of Drug Discovery

Ikuo Horii; Hiroshi Yamada; Rie Kikkawa; Toshinori Yamamoto; Tamio Fukushima; Kaori Tomizawa


Journal of Toxicological Sciences | 2005

Comparison between in vitro- and in vivo-hepatotoxicity for the investigation of a hepatotoxicity screening system in primary cell cultures(Liver, Alimentary system, Proceedings of the 32nd Annual Meeting)

Rie Kikkawa; Masaaki Fujikawa; Toshinori Yamamoto; Ikuo Horii


Journal of Toxicological Sciences | 2005

Investigation of protein expression induced by hepatotoxicants in rat hepatocytes cultures and livers(Proceedings of the 32nd Annual Meeting)

Toshinori Yamamoto; Rie Kikkawa; Hiroshi Yamada; Ikuo Horii

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