Rob Baxter

PDQ Wizard: automated prioritization and characterization of gene and protein lists using biomedical literature

SUMMARYnPDQ Wizard automates the process of interrogating biomedical references using large lists of genes, proteins or free text. Using the principle of linkage through co-citation biologists can mine PubMed with these proteins or genes to identify relationships within a biological field of interest. In addition, PDQ Wizard provides novel features to define more specific relationships, highlight key publications describing those activities and relationships, and enhance protein queries. PDQ Wizard also outputs a metric that can be used for prioritization of genes and proteins for further research.nnnAVAILABILITYnPDQ Wizard is freely available from http://www.gti.ed.ac.uk/pdqwizard/.

Bringing the grid to the biomedical workbench

Modem biological research is data intensive and relies on an efficient informatics infrastructure. Research on the genetic control of embryo development involves large volume image data requiring significant computing resources for reconstruction, mapping and analysis. This poster describes a demonstrator for delivering secure and transparent access to high-performance computing to the laboratory workbench using Grid technologies, in this case for 3D reconstruction from OPT microscopy.