Robert A. Archer | Researchain

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Featured researches published by Robert A. Archer.

Journal of Organic Chemistry | 1977

Cannabinoids. 3. Synthetic approaches to 9-ketocannabinoids. Total synthesis of nabilone.

Robert A. Archer; W. B. Blanchard; William A. Day; Douglas W. Johnson; Edward Ralph Lavagnino; C. W. Ryan; Jack E. Baldwin

Aufgrund des klinischen Interesses von Nabilon (VIa) werden verschiedene Synthesen zur Herstellung dieser Verbindung beschrieben, die an bekannte Verfahren anschliesen.

Cellular and Molecular Life Sciences | 1972

CMR spectral analysis of tetrahydrocannabinol and its isomers

E. Wenkert; D. W. Cochran; F. M. Schell; Robert A. Archer; K. Matsumoto

Die13C-NMR-Spektren des Tetrahydrocannabinols und seiner Isomeren wurden aufgenommen und vollständig analysiert.

Cellular and Molecular Life Sciences | 1977

Microbiological transformation of cannabinoids.

Bernard J. Abbott; David S. Fukuda; Robert A. Archer

Microorganisms were screened for their ability to modify 2 synthetic cannabinoid substrates (I andII). Structure analyses revealed that microorganisms transformed the substrates by (a) primary oxidation of the side chain, β-oxidation of the side chain, ketone formation on the side chain or cyclohexene ring, (b) secondary hydroxylation on the side chain, (c) aromatization of the cyclohexene ring, and (d) tertiary hydroxylation at the b/c ring juncture.

Archive | 1979