Robert A. Moore

Testicular tumors: A clinicopathological study

Summary The classification of testicular tumors arrived at in this study is based on both the morphological and the biological characteristics of the tumors. The primary division of testicular tumors is into (1) the germinal tumors, which arise from germ cells and make up 96.5 per cent of this series, and (2) the nongerminal tumors, a miscellaneous group of neoplasms arising from the nongerminal elements of the testis and comprising 3.5 per cent of this series. The germinal tumors are composed of any one or any combination of four morphological tumor patterns: seminoma, embryonal carcinoma, teratoma, and choriocarcinoma. On the basis of biological behavior and apparent morphogenesis, the fifteen possible morphological varieties of tumors can be put in five groups: I. seminoma, pure; II. embryonal carcinoma, pure, or with seminoma; III. teratoma, pure, or with seminoma; IV. teratoma with either embryonal carcinoma or choriocarcinoma or both, and with or without seminoma; V. choriocarcinoma, pure, or with either embryonal carcinoma or seminoma or both.