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Robert A. Strelitz

Merck & Co.

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Featured researches published by Robert A. Strelitz.

Bioorganic & Medicinal Chemistry Letters | 1994

Quinazolinone biphenyl acylsulfonamides: a potent new class of angiotensin-II receptor antagonists

Prasun K. Chakravarty; Robert A. Strelitz; Tsing-Bau Chen; Raymond S.L. Chang; Victor J. Lotti; Gloria J. Zingaro; Terry W. Schorn; Salah D. Kivlighn; Peter K.S. Siegel; Arthur A. Patchett; William J. Greenlee

Abstract A new series of quinazolinone-based AT 1 selective antagonists, bearing acylsulfonamides (-SO 2 NHCOR) as the tetrazole bioisosteres, was evaluated. While AT 1 potencies remained similar to the tetrazole analogs, the AT 2 receptor affinities were significantly improved with the introduction of acylsulfonamide groups. Several of these antagonists displayed improved in vivo properties.

Archive | 1984

N-alkylguanine acyclonucleosides as antiviral agents

Malcolm Maccoss; Richard L. Tolman; Robert A. Strelitz

Archive | 1977

Composition for secondary and tertiary oil recovery

Nathaniel Grier; Richard A. Dybas; Robert A. Strelitz

Journal of Pharmaceutical Sciences | 1976

Synthesis and biological evaluation of 1‐(4‐hydroxy‐2‐oxo‐2H‐1‐benzopyran‐3‐yl)pyridinium hydroxide inner salt derivatives

Nathaniel Grier; Robert A. Strelitz

Archive | 1976

Alicyclic alkylene polyamine microorganism and algae growth inhibitors

Bruce E. Witzel; Nathaniel Grier; Richard A. Dybas; Robert A. Strelitz

Journal of Pharmaceutical Sciences | 1982

Antibacterial iV-[ω,ώ-Bis(alicyclic and aryl)-sec-alkyl]-l,3-diamino-2-propanol Dihydrochloride Salts

Nathaniel Grier; Richard A. Dybas; Robert A. Strelitz; Bruce E. Witzel; Eugene L. Dulaney

Archive | 1977

Novel dibicyclo [3.1.1] and [2.2.1] heptyl and dibicyclo [3.1.1] and [2.2.1] heptenyl polyamines

Nathaniel Grier; Richard A. Dybas; Robert A. Strelitz

Archive | 1976

Novel dibicyclo [3.1.1] and [2.2.1] heptyl and dibicyclo [3.1.1] and [2.2.1] heptenyl polyamines and methods for their preparation

Nathaniel Grier; Richard A. Dybas; Robert A. Strelitz

Archive | 1976

Dibicyclo[3.1.1] and [2.2.1] heptyl and dibicyclo [3.1.1] and [2.2.1] heptenyl polyamines having a piperidine moiety

Nathaniel Grier; Richard A. Dybas; Robert A. Strelitz

Archive | 1985

N-Alkylguanin-Acyclonucleoside als antivirale Mittel

Malcolm Maccoss; Richard L. Tolman; Robert A. Strelitz

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Nathaniel Grier

Merck

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Richard A. Dybas

Merck

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Bruce E. Witzel

Merck

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Malcolm Maccoss

Merck

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Richard L. Tolman

Merck

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Arthur A. Patchett

Merck

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Eugene L. Dulaney

Merck

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Gloria J. Zingaro

United States Military Academy

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Peter K.S. Siegel

United States Military Academy

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Prasun K. Chakravarty

Merck

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