Robert C. Mellors

Phosphatase Activity in Chromatolytic Nerve Cells.

Summary Markedly increased acid phosphatase activity has been found in regions of the cytoplasm of nerve cells in which chromatolysis has been produced by axon section. This increased activity is proportional to the degree of chromatolysis, and is thus probably associated with increased nucleoprotein synthesis or degradation.

Structural Heterogeneity in p30 Molecules of Type C Viruses

Tryptic digests of p30 proteins from mouse type C viruses were subjected to cation-exchange chromatography. Structural heterogeneity of p30 molecules was seen in two specific areas of the peptide elution profiles. These hypervariable regions of p30 proteins were used to discriminate representative ecotropic (N- and B-tropic), xenotropic (alpha and beta) and amphotropic viruses.