Robert Frank Santerre
Eli Lilly and Company
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Featured researches published by Robert Frank Santerre.
Gene | 1984
Robert Frank Santerre; Norris E. Allen; Joe N. Hobbs; R.Nagaraja Rao; Robert J. Schmidt
Novel bacterial resistance genes were cloned and expressed as dominant selection markers in mammalian cells. Escherichia coli genes coding for resistance to the aminocyclitol antibiotics hygromycin B (Hm) and G418 were cloned into the eukaryotic expression plasmid pSV5GPT [Mulligan and Berg, Proc. Natl. Acad. Sci. USA 78 (1981) 2072-2076]. Mouse cells normally sensitive to 100 micrograms/ml Hm were transformed with these plasmids and selected in 200 micrograms/ml Hm. Transformants resistant to as much as 1 mg/ml Hm and 500 micrograms/ml G418 were isolated. Cell extracts contained an acetyltransferase activity capable of acetylating G418 and an Hm aminocyclitol phosphotransferase activity. Plasmid DNA sequences were identified by Southern blot analysis of high Mr DNA isolated from transformed cells.
Proceedings of the National Academy of Sciences of the United States of America | 1981
Robert Frank Santerre; Roland A. Cook; Rae Marie D. Crisel; John D. Sharp; Robert J. Schmidt; Daniel C. Williams; Christine P. Wilson
Archive | 1983
Robert Frank Santerre; Ramachandra Nagaraja Rao
Nucleic Acids Research | 1985
Robert John Beckmann; Robert Schmidt; Robert Frank Santerre; Jorge Plutzky; Gerald R. Crabtree; George Louis Long
Archive | 1985
Nils U. Bang; Robert John Beckmann; S. Richard Jaskunas; Mei-Huei T. Lai; Shelia P. Little; George Louis Long; Robert Frank Santerre
Biochemical and Biophysical Research Communications | 1996
Edward M. Johnstone; Lael E. Babbey; Diane T. Stephenson; Donald C. Paul; Robert Frank Santerre; James A. Clemens; Daniel C. Williams; Sheila P. Little
Archive | 1986
Nils U. Bang; Robert John Beckmann; Stanley Richard Jaskunas; Mei-Huei Tsai Lai; Sheila P. Little; George Louis Long; Robert Frank Santerre
Archive | 1988
Nils U. Bang; Robert John Beckmann; S. Richard Jaskunas; Mei-Huei T. Lai; Sheila P. Little; George Louis Long; Robert Frank Santerre
Archive | 1998
Henry U. Bryant; Robert Frank Santerre
Neuroscience Letters | 1994
Edward M. Johnstone; Tilman Oltersdorf; Kelly R. Bales; Michael O. Chaney; Robert Frank Santerre; Sheila P. Little