Robert J. Hardie

Ultrasound-guided percutaneous drainage as the primary treatment for prostatic abscesses and cysts in dogs.

Thirteen dogs with prostatic abscesses and cysts were treated using percutaneous ultrasound-guided drainage. Eight dogs were diagnosed with prostatic abscesses and five with cysts on the basis of cytopathological examination and bacterial culture of the prostatic fluid. Antibiotic therapy, based on culture and sensitivity results, was administered for a minimum of 4 weeks. Intact dogs were castrated after initial drainage. Repeat ultrasonography of the prostate was performed every 1 to 6 weeks, and any residual cavitary lesions were drained and fluid analysis repeated. The median number of drainage procedures required to completely resolve the lesions was two (range, one to four). No complications were observed after drainage, and clinical signs resolved in all dogs. None of the dogs developed clinical signs of recurrent abscesses or cysts in the follow-up period (median, 36 months; range, 10 to 50 months). Ultrasound-guided, percutaneous drainage of prostatic abscesses and cysts appears to be a useful alternative to surgical treatment in select dogs.

Spontaneous Pneumothorax Caused by Pulmonary Blebs and Bullae in 12 Dogs

Spontaneous pneumothorax caused by pulmonary blebs and bullae was diagnosed in 12 dogs based on history, clinical examination, thoracic radiographs, surgical findings, and histopathological examination of resected pulmonary lesions. Radiographic evidence of blebs or bullae was seen in only one dog. None of the dogs responded to conservative treatment with thoracocentesis or thoracostomy tube drainage. A median sternotomy approach was used to explore the thorax in all dogs. Pulmonary blebs and bullae were resected with partial or complete lung lobectomy. Ten of the dogs had more than one lesion, and seven of the dogs had bilateral lesions. The cranial lung lobes were most commonly affected. Histopathology results of the blebs and bullae were consistent in all dogs and resembled lesions found in humans with primary spontaneous pneumothorax. None of the dogs developed recurrence of pneumothorax. Median follow-up time was 19 months. The outcome following resection of the pulmonary blebs and bullae was excellent.

Spinal meningeal cyst in a dog: a case report and literature review

A two-year-old, female Chinese shar pei was presented with a one-year history of ataxia involving the pelvic limbs. The neurological lesion was localized to the thoracolumbar region of the spinal cord. A cyst involving the dorsal subarachnoid space at the level of the 12th thoracic vertebral body was identified with myelography. The diagnosis of a meningeal cyst was made, and surgical treatment consisting of a dorsal laminectomy and cyst fenestration was performed. The pelvic-limb ataxia improved, and the owners considered the dog to be normal three months after surgery. The classification, etiology, clinical signs, diagnostic techniques, treatment, and histology of meningeal cysts are reviewed.

Arytenoid Lateralization for Treatment of Laryngeal Paralysis in 10 Cats

OBJECTIVE To describe the signalment, history, clinical signs, surgical technique, and outcome for cats with laryngeal paralysis that had arytenoid lateralization. STUDY DESIGN Case series. ANIMALS Cats with laryngeal paralysis (n=10). METHODS Medical records (1996-2002) for cats with laryngeal paralysis that had arytenoid lateralization were reviewed for signalment, history, clinical signs, degree of paralysis, cause, concurrent medical conditions, surgical technique, and outcome. Follow-up information was obtained from owners or referring veterinarians. RESULTS Of 10 cats, 9 had bilateral and 1 had unilateral laryngeal paralysis. Arytenoid lateralization were unilateral (n=7), bilateral (1), and staged bilateral procedures (2), 10 days and 3 years apart, respectively. Postoperatively, 1 cat had persistent inspiratory noise because of minimal enlargement of the rima glottidis and 2 cats required a temporary tracheostomy for management of laryngeal swelling. Three cats developed aspiration pneumonia and died 4, 7, and 150 days after surgery; all 3 had bilateral (simultaneous or staged) procedures. Of the 7 remaining cats, 4 were alive at follow-up and 3 had died of causes unrelated to arytenoid lateralization. The calculated mean survival time for all 10 cats was 406 days (median, 150 days; range, 4-1825 days). CONCLUSIONS Arytenoid lateralization was effective at enlarging the rima glottidis and reducing signs of airway obstruction in most cats. CLINICAL RELEVANCE Unilateral arytenoid lateralization is a feasible option for the surgical management of cats with marked clinical signs; however, bilateral procedures should be avoided or at least performed with considerable caution because of the apparent risk for aspiration pneumonia.

Use of a Custom Orthotic Boot for Management of Distal Extremity and Pad Wounds in Three Dogs

Objective To describe use of a custom orthotic boot for management of distal extremity and pad wounds in dogs. Study Design Clinical report. Animals Dogs (n = 3). Methods A custom orthotic boot made of lightweight copolymer plastic was used to immobilize the distal extremity and protect full-thickness wounds involving the medial or lateral aspect of the metatarsus including a portion of the metatarsal pad in 3 dogs. Boots were made in a bivalve design with closed-cell foam padding and adjustable straps that allowed for easy application. They were molded with the tarsocrural joint in slight hyperextension and the metatarsophalangeal joints in a neutral position so that the wounds and metatarsal pads were “off weighted” when the dogs were standing. In addition, a “window” was cut out directly over the wounds to minimize direct contact between the boot and the wound. Results Wounds healed by contraction and epithelialization in 21, 21, and 45 days. The only complication encountered was mild skin irritation at the top of the boot in 2 dogs that was managed with additional closed-cell foam padding. Conclusion A custom orthotic boot was effective at immobilizing the distal extremity and reducing contact between the wound and the boot which allowed for complete healing by contraction and epithelialization.

Perioperative Complications after Full‐Thickness Gastrointestinal Surgery in Cats with Alimentary Lymphoma

Objective To determine perioperative risk factors for complications that occur before hospital discharge after gastrointestinal (GI) surgery in cats with alimentary lymphosarcoma (LSA). Study Design Case series. Animals Cats (n=70) with a histopathologically confirmed diagnosis of alimentary LSA that had full-thickness GI surgery. Methods Medical record data (February 1996–March 2009) from 3 academic referral centers were reviewed. Retrieved data included signalment, preoperative clinical signs and laboratory findings, perioperative medications administered, type and location of GI surgery performed and outcome until hospital discharge. Results In 38 surgeries, intestinal resection and anastomosis was performed. Gastrotomy and/or enterotomy was performed in 53 surgeries. A preoperative serum albumin concentration <2.5 g/dL was recorded for 11 cases. There was no clinical evidence of postoperative leakage from any biopsy or anastomosis site. Postoperative complications that occurred before hospital discharge included: anorexia or decreased appetite (n=8), hyperthermia (3), pancreatitis (1) and constipation (1). Conclusions Cats with alimentary LSA do not appear to be at high risk of postoperative dehiscence after full-thickness GI surgery.OBJECTIVE To determine perioperative risk factors for complications that occur before hospital discharge after gastrointestinal (GI) surgery in cats with alimentary lymphosarcoma (LSA). STUDY DESIGN Case series. ANIMALS Cats (n=70) with a histopathologically confirmed diagnosis of alimentary LSA that had full-thickness GI surgery. METHODS Medical record data (February 1996-March 2009) from 3 academic referral centers were reviewed. Retrieved data included signalment, preoperative clinical signs and laboratory findings, perioperative medications administered, type and location of GI surgery performed and outcome until hospital discharge. RESULTS In 38 surgeries, intestinal resection and anastomosis was performed. Gastrotomy and/or enterotomy was performed in 53 surgeries. A preoperative serum albumin concentration <2.5 g/dL was recorded for 11 cases. There was no clinical evidence of postoperative leakage from any biopsy or anastomosis site. Postoperative complications that occurred before hospital discharge included: anorexia or decreased appetite (n=8), hyperthermia (3), pancreatitis (1) and constipation (1). CONCLUSIONS Cats with alimentary LSA do not appear to be at high risk of postoperative dehiscence after full-thickness GI surgery.

Evaluation of Submucosally Injected Polyethylene Glycol‐Based Hydrogel and Bovine Cross‐Linked Collagen in the Canine Urethra using Cystoscopy, Magnetic Resonance Imaging and Histopathology

OBJECTIVE To (1) investigate the tissue response to a novel urethral bulking agent, polyethylene glycol carboxymethyl cellulose hydrogel (PEG-CMC) injected submucosally in the canine urethra and (2) compare PEG-CMC with bovine collagen (BC), the current standard for urethral bulking. STUDY DESIGN Experimental study. ANIMALS Purpose-bred female hound dogs (n = 8). METHODS Standardized submucosal urethral injections of BC and PEG-CMC were performed in 8 female dogs. Injection sites were evaluated by cystoscopy on days 0 (n = 8), 30 (n = 4), and 90 (n = 4), magnetic resonance imaging on days 0 (n = 8), 30 (n = 8), and 90 (n = 4) and by histopathology on days 30 (n = 4) and 90 (n = 4). RESULTS Both PEG-CMC and BC were detectable on MRI as hyperintense foci on T2-weighted images. Grossly, PEG-CMC formed more prominent blebs than BC. On follow-up cystoscopic examination, 6/8 PEG-CMC injection needle tracts were visible, and 3 of these sites had mucosal erosions. Histopathologic scores for foreign body reaction and inflammation were significantly higher for PEG-CMC compared with BC (P < 0.005). BC elicited a lymphoplasmacytic reaction whereas PEG-CMC incited a granulomatous response. CONCLUSIONS The overall physical characteristics and histologic response associated with PEG-CMC support its use as a urethral bulking agent; however, the current formulation needs to be adjusted for clinical use.Objective To (1) investigate the tissue response to a novel urethral bulking agent, polyethylene glycol carboxymethyl cellulose hydrogel (PEG-CMC) injected submucosally in the canine urethra and (2) compare PEG-CMC with bovine collagen (BC), the current standard for urethral bulking. Study design Experimental study. Animals Purpose-bred female hound dogs (n = 8). Methods Standardized submucosal urethral injections of BC and PEG-CMC were performed in 8 female dogs. Injection sites were evaluated by cystoscopy on days 0 (n = 8), 30 (n = 4), and 90 (n = 4), magnetic resonance imaging on days 0 (n = 8), 30 (n = 8), and 90 (n = 4) and by histopathology on days 30 (n = 4) and 90 (n = 4). Results Both PEG-CMC and BC were detectable on MRI as hyperintense foci on T2-weighted images. Grossly, PEG-CMC formed more prominent blebs than BC. On follow-up cystoscopic examination, 6/8 PEG-CMC injection needle tracts were visible, and 3 of these sites had mucosal erosions. Histopathologic scores for foreign body reaction and inflammation were significantly higher for PEG-CMC compared with BC (P < 0.005). BC elicited a lymphoplasmacytic reaction whereas PEG-CMC incited a granulomatous response. Conclusions The overall physical characteristics and histologic response associated with PEG-CMC support its use as a urethral bulking agent; however, the current formulation needs to be adjusted for clinical use.

Use of the PleuralPort device for management of pleural effusion in six dogs and four cats.

OBJECTIVE To describe the placement technique, complications, and outcomes associated with use of the PleuralPort device for management of pleural effusion in dogs and cats. STUDY DESIGN Case Series. ANIMALS Six dogs and 4 cats. METHODS Medical records of all animals with pleural effusion managed with the PleuralPort device were reviewed. Data regarding signalment, fluid analysis, placement technique, duration of function, duration of implantation, complications, and outcome were collected. Owners and referring veterinarians were contacted for follow-up information. RESULTS Nine animals had chylous effusion and 1 dog had pleural carcinomatosis. Eleven ports were placed with 1 cat receiving bilateral ports. Four animals developed complications. One cat developed pneumothorax immediately after implantation and was euthanatized. In 2 dogs and 1 cat, the ports obstructed. The 6 remaining animals had functioning ports at time of death or resolution of effusion and no longer required use of the port. No significant port migration, irritation, or infection of the device was reported. Excluding the cat with pneumothorax, median duration of port function was 20 days (range 1-391), and median duration of port implantation was 391 days (range 6-723). CONCLUSIONS The PleuralPort device is a feasible option for the management of pleural effusion in dogs and cats.Objective To describe the placement technique, complications, and outcomes associated with use of the PleuralPort device for management of pleural effusion in dogs and cats. Study Design Case Series. Animals Six dogs and 4 cats. Methods Medical records of all animals with pleural effusion managed with the PleuralPort device were reviewed. Data regarding signalment, fluid analysis, placement technique, duration of function, duration of implantation, complications, and outcome were collected. Owners and referring veterinarians were contacted for follow-up information. Results Nine animals had chylous effusion and 1 dog had pleural carcinomatosis. Eleven ports were placed with 1 cat receiving bilateral ports. Four animals developed complications. One cat developed pneumothorax immediately after implantation and was euthanatized. In 2 dogs and 1 cat, the ports obstructed. The 6 remaining animals had functioning ports at time of death or resolution of effusion and no longer required use of the port. No significant port migration, irritation, or infection of the device was reported. Excluding the cat with pneumothorax, median duration of port function was 20 days (range 1–391), and median duration of port implantation was 391 days (range 6–723). Conclusions The PleuralPort device is a feasible option for the management of pleural effusion in dogs and cats.

Surgical excision of the parotid salivary gland for treatment of a traumatic mucocele in a dog.

A 3 yr old spayed female mixed-breed German shepherd dog was presented with a right facial swelling that developed after fighting with another dog. A parotid salivary mucocele was diagnosed via physical examination, fine-needle aspirate, and sialography of the parotid and mandibular salivary glands. Surgical excision of the right parotid salivary gland and duct was performed along with drainage of the mucocele. Neither intraoperative nor postoperative complications occurred, and follow-up examination 4 mo later revealed no evidence of recurrence. Case outcome was considered excellent. Sialography was useful for confirming the parotid gland as the source of the mucocele. Surgical excision of the parotid salivary gland is technically challenging, but an effective treatment option for traumatic mucoceles in the dog.

Translaryngeal percutaneous arytenoid lateralization technique in a canine cadaveric study.

Objective To describe the technique for translaryngeal percutaneous arytenoid lateralization (TPAL) and the effect on rima glottidis cross-sectional area using a canine cadaveric model. Study design Ex vivo study. Animals Canine cadavers (n = 9). Materials and Methods With the aid of a laryngoscope, the larynx was visualized and a mattress suture (double-armed 2-0 polypropylene) was placed through the right arytenoid cartilage and exited the skin ventral to the jugular vein. The ends of the suture were passed through a button and tied on the skin to lateralize the right arytenoid cartilage. Digital images of the larynx were made before and after suture placement. Mean (±SD) rima glottidis cross-sectional area (mm2) was calculated from the digital images and values before and after suture placement were compared using a paired t-test. A P value < 0.05 was considered significant. Change in cross-sectional area was expressed as percent increase. Results Suture placement and the degree of arytenoid lateralization was relatively consistent in all dogs. Mean (±SD) cross-sectional area of the rima glottidis was 126.3 mm2 (±7.74) before and 172.1 mm2 (±24.7) after suture placement (P = 0.004). Mean percent increase in cross-sectional area was 25%. Conclusion The TPAL technique was effective at enlarging the rima glottidis in this canine cadaveric model. TPAL is rapid to perform and does not require specialized instrumentation. Results of this study support further investigation of the TPAL technique as an alternative to temporary tracheostomy for dogs in severe respiratory distress due to laryngeal paralysis.OBJECTIVE To describe the technique for translaryngeal percutaneous arytenoid lateralization (TPAL) and the effect on rima glottidis cross-sectional area using a canine cadaveric model. STUDY DESIGN Ex vivo study. ANIMALS Canine cadavers (n = 9). MATERIALS AND METHODS With the aid of a laryngoscope, the larynx was visualized and a mattress suture (double-armed 2-0 polypropylene) was placed through the right arytenoid cartilage and exited the skin ventral to the jugular vein. The ends of the suture were passed through a button and tied on the skin to lateralize the right arytenoid cartilage. Digital images of the larynx were made before and after suture placement. Mean (±SD) rima glottidis cross-sectional area (mm(2) ) was calculated from the digital images and values before and after suture placement were compared using a paired t-test. A P value < 0.05 was considered significant. Change in cross-sectional area was expressed as percent increase. RESULTS Suture placement and the degree of arytenoid lateralization was relatively consistent in all dogs. Mean (±SD) cross-sectional area of the rima glottidis was 126.3 mm(2) (±7.74) before and 172.1 mm(2) (±24.7) after suture placement (P = 0.004). Mean percent increase in cross-sectional area was 25%. CONCLUSION The TPAL technique was effective at enlarging the rima glottidis in this canine cadaveric model. TPAL is rapid to perform and does not require specialized instrumentation. Results of this study support further investigation of the TPAL technique as an alternative to temporary tracheostomy for dogs in severe respiratory distress due to laryngeal paralysis.