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Dive into the research topics where Robert J. Nickles is active.

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Featured researches published by Robert J. Nickles.


Journal of Computer Assisted Tomography | 1979

DESIGN OF A THREE-DIMENSIONAL POSITRON CAMERA FOR NUCLEAR MEDICINE

Robert J. Nickles; Hans O. Meyer; Rodney A. Brooks

A positron camera is proposed for nuclear medical imaging of radionuclide distributions in a series of isolated planes. This three-dimensional localisation is achieved through analysis of four time signals, whose differences directly measure the position (x, y, z) of individual positron annihilation events. A tetrahedronal symmetry is exploited, with two skewed plastic scintillator bars spanning a large sensitive volume. Phototubes on each end of both bars generate fast timing pulses uniquely determining the decay position through a time-of-flight technique. The mathematical properties of the transformation from the observed quantities to the spatial distribution of the radionuclide are investigated. A discussion of the efficiency of the system and the effects of Compton scattering in tissue is given. A one-dimensional pilot study encourages the development of the prototype three-dimensional positron camera.


Radiology | 1977

Use of a generalized modular data handling system in nuclear medicine.

James E. Holden; Robert J. Nickles; Aaro Kluru; R. E. Polcyn

Addition of a CAMAC modular data handling system to a small computer used for gamma-camera work has allowed the acquisition and processing of a broad variety of nuclear medicine data. Significant contributions have been made ranging from clinical renal evaluation to radiopharmaceutical development. Digital rectilinear scanning and computer acquisition of physiological signals such as the electrocardiogram are other applications. The system provides an inexpensive means of matching present-day nuclear computers to the diversity of data.


Archive | 1975

Three-dimensional time-of-flight gamma camera system

Robert J. Nickles; Hans O. Meyer


Archive | 1992

Method for localization and treatment of tumors using polylysine complexes

Steven Kornguth; Patrick Turski; H. Ian Robins; Robert J. Nickles


Archive | 1977

Method and apparatus for multiplexing of physiological sensor signals with gamma ray camera data signals

Robert J. Nickles


Archive | 1977

Correction of data loss in gamma ray scintillation cameras

Robert J. Nickles


Archive | 2001

Synthesis of 17F labeled fluoroalkanes

Andrew D. Roberts; Robert J. Nickles


Archive | 2002

Positron gun for pet attenuation measurements

Robert J. Nickles


Archive | 1990

Method for localization and treatment of tumors and complexes therefor

Steven Kornguth; Patrick A. Turski; H. Ian Robins; Robert J. Nickles


Archive | 1999

Dopamine System Characterization of Rhesus Monkeys Exposed to Moderate Dose Alcohol in Utero

Andrew D. Roberts; Onofre T. DeJesus; Mary L. Schneider; M. J. Schueller; Steven E. Shelton; Robert J. Nickles; Jogeshwar Mukherjee

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Andrew D. Roberts

Minnesota State University

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M. J. Schueller

Brookhaven National Laboratory

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Alexander K. Converse

University of Southern California

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David W. Dick

University of Wisconsin-Madison

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Dhanabalan Murali

University of Wisconsin-Madison

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Kevin Dabbs

University of Wisconsin-Madison

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Onofre T. DeJesus

University of Wisconsin-Madison

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Mary L. Schneider

University of Wisconsin-Madison

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Steven E. Shelton

University of Wisconsin-Madison

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Todd E. Barnhart

University of Wisconsin-Madison

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