Robert John Wilson
Codexis
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Publication
Featured researches published by Robert John Wilson.
Journal of Organic Chemistry | 2018
Yong Koy Bong; Shiwei Song; Jovana Nazor; Michael Vogel; Magnus Widegren; Derek Smith; Steven J. Collier; Robert John Wilson; S. M. Palanivel; Karthik Narayanaswamy; Ben Mijts; Michael D. Clay; Ryan Fong; Jeff Colbeck; Amritha Appaswami; Sheela Muley; Jun Zhu; Xiyun Zhang; Jack Liang; David Entwistle
A wild-type Baeyer-Villiger monooxygenase was engineered to overcome numerous liabilities in order to mediate a commercial oxidation of pyrmetazole to esomeprazole, using air as the terminal oxidant in an almost exclusively aqueous reaction matrix. The developed enzyme and process compares favorably to the incumbent Kagan inspired chemocatalytic oxidation, as esomeprazole was isolated in 87% yield, in >99% purity, with an enantiomeric excess of >99%.
Archive | 2010
Lynne Gilson; Steven J. Collier; Joly Sukumaran; Wan Lin Yeo; Oscar Alvizo; Ee Ling Teo; Robert John Wilson; Junye Xu
Archive | 2010
Steven J. Collier; Ee Ling Teo; Joly Sukumaran; Robert John Wilson; Junye Xu
Archive | 2010
Steven J. Collier; Jack Liang; Fan Jasyln Fu; Robert John Wilson
Archive | 2016
Ee Lui Ang; Oscar Alvizo; Behnaz Behrouzian; Michael D. Clay; Steven J. Collier; Ellen Eberhard; Fu Fan; Shiwei Song; Derek Smith; Magnus Widegren; Robert John Wilson; Junye Xu; Jun Zhu
Archive | 2015
Steven J. Collier; Ee Ling Teo; Joly Sukumaran; Robert John Wilson; Junye Xu
Archive | 2011
Ee Lui Ang; Michael D. Clay; Behnaz Behrouzian; Ellen Eberhard; Steven J. Collier; Fan Jasyln Fu; Derek Smith; Shiwei Song; Oscar Alvizo; Magnus Widegren; Jun Zhu; Junye Xu; Robert John Wilson
Archive | 2011
Ee Lui Ang; Michael D. Clay; Behnaz Behrouzian; Ellen Eberhard; Steven J. Collier; Fan Jasyln Fu; Derek Smith; Shiwei Song; Oscar Alvizo; Magnus Widegren; Jun Zhu; Junye Xu; Robert John Wilson
Archive | 2010
Lynne Gilson; Steven J. Collier; Joly Sukumaran; Wan Lin Yeo; Oscar Alviso; Ee Ling Teo; Robert John Wilson; Junye Xu
Archive | 2010
Steven J. Collier; Ee Ling Teo; Joly Sukumaran; Robert John Wilson; Junye Xu
