Robert T. Manning

The Use of Alkylating Agents in the Treatment of Wegener's Granulomatosis

Excerpt Wegeners granulomatosis, a rare disease of unknown etiology, was first described by Klinger (1) in 1931. Wegener (2), in 1936, reported three additional patients, recognizing the syndrome ...

Serum Arginase Activity.

Summary Serum arginase activity has been determined in 34 healthy blood donors. A mean value 0.06 ± 0.09 μmole urea formed/ml serum was found with a range of .00 to 0.36 μmole. In sera of 19 patients with proven or suspected liver disease the mean arginase activity was 1.36 with a range of .00 to 6.08 μmoles formed/ml serum under the condition of assay.

Dictation of the discharge resumé: a forgotten link between the spoken and written word.

SummaryAll medical personnel use jargon when conversing about patients. Such jargon can be clarified by questions asked at the moment of discussion. The reader of a discharge summary, however, does not have the option of questioning the author if meanings are ambiguous and vague. Editing discharge summaries is an impossible task—I’ve tried it and quit, partly from laughing, partly from crying, and mostly because the head record librarian refused to have all the summaries retyped. Save time in the record room by being more concise and clear in your dictation, then use the time you have saved for more rewarding activities. Organize your thoughts, dictate, then go smell the flowers with the recovered time.

Physical Signs of Cirrhosis

There are many physical signs or “cirrhosis clues” which can help physicians recognize cirrhosis of the liver early, when there is the best chance for satisfactory management, A larger group of signs appear later and often represent secondary manifestations of the cirrhotic process, but nevertheless are of some value in anticipating and managing complications.