Roberto Di Domenico | Researchain

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Featured researches published by Roberto Di Domenico.

Synthetic Communications | 1997

Synthesis of 1,4-Dihydropyridines by Regioselective Additions of Benzylic Zinc Bromides to Pyridinium Salts and Their Aromatizations to 4-Benzylpyridines

A. Paul Krapcho; David J. Waterhouse; Abdelhakim Hammach; Roberto Di Domenico; Ernesto Menta; Ambrogio Oliva; Silvano Spinelli

Abstract Benzylic zinc reagents add with high regioselectivity to 1-(phenoxycarbonyl) salts of methyl nicotinate to yield methyl-1-(phenoxylcarbonyl)-4-benzyl-1,4-dihydronicotinates. The dihydronicotinates on heating with sulfur in decalin afford methyl 4-benzylnicotinates.

Clinical Cancer Research | 2000

BBR 3464: A Novel Triplatinum Complex, Exhibiting a Preclinical Profile of Antitumor Efficacy Different from Cisplatin

Carla Manzotti; Graziella Pratesi; Ernesto Menta; Roberto Di Domenico; Ennio Cavalletti; Heinz H. Fiebig; Lloyd R. Kelland; Nicholas Farrell; Donatella Polizzi; Rosanna Supino; Gabriella Pezzoni; Franco Zunino

Archive | 1992

Heterocyclic amines useful in the therapy of asthma and inflammation of the respiratory tract

Giorgio Long; Carmelo Gandolfi; Gianpiero De Cillis; Roberto Di Domenico; Antonella Rozzi; Licia Gallico

Journal of Medicinal Chemistry | 1998

Synthesis and Antitumor Evaluation of 2,5-Disubstituted- Indazolo[4,3-gh]isoquinolin-6(2H)-ones (9-Aza-anthrapyrazoles)

A. Paul Krapcho; Ernesto Menta; Ambrogio Oliva; Roberto Di Domenico; Luigi Fiocchi; Martin E. Maresch; Cynthia E. Gallagher; Miles P. Hacker; Gino Beggiolin; Fernando Giuliani; and Gabriella Pezzoni; Silvano Spinelli

Journal of Medicinal Chemistry | 1995

N-acyl-2-substituted-1,3-thiazolidines, a new class of non-narcotic antitussive agents: studies leading to the discovery of ethyl 2-[(2-methoxyphenoxy)methyl]-beta-oxothiazolidine-3-propanoate.

Carmelo Gandolfi; Roberto Di Domenico; Silvano Spinelli; Licia Gallico; Luigi Fiocchi; Andrea Lotto; Ernesto Menta; Alessandra Borghi; Carla Dalla Rosa; Sergio Tognella

Archive | 1990

A process for preparation of enantiomerically pure polysubstituted 1,4-dihydropyridines

Carmelo Gandolfi; Marco Frigerio; Carlo Riva; Andrea Zaliani; Giorgio Long; Roberto Di Domenico

Journal of Heterocyclic Chemistry | 1995

Synthesis of 4-hydroxy-6,9-difluorobenz[g]isoquinoline-5,10-diones and conversions to 4-hydroxy-6,9-bis[(aminoalkyl)amino]-benz[g]isoquinoline-5,10-diones

A. Paul Krapcho; Martin J. Maresch; Cynthia E. Gallagher; Miles P. Hacker; Ernesto Menta; Ambrogio Oliva; Roberto Di Domenico; Giovanni Da Re; Silvano Spinelli

Archive | 1989

β-carbonyl-carboxyamides of 1,3-thiazolidines

Carmelo Gandolfi; Roberto Di Domenico; Silvano Spinelli; Licia Gallico; Bruno Lumachi; Sergio Tognella

Archive | 1998

Multinuclear cationic platinum complexes with antitumor activity

Giovanni Da Re; Roberto Di Domenico; Silvano Spinelli; Nicholas Farrell

Journal of Heterocyclic Chemistry | 1998

SYNTHESIS OF HYDROXY-SUBSTITUTED AZA-ANALOGUES OF ANTITUMOR ANTHRAPYRAZOLES

A. Paul Krapcho; Cynthia E. Gallagher; Abdelhakim Hammach; Miles P. Hacker; Ernesto Menta; Ambrogio Oliva; Roberto Di Domenico; Giovanni Da Re; Andrea Lotto; Silvano Spinelli

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