Robin M. Murray

Poster #88 INCIDENCE OF PSYCHOTIC DISORDERS IN PALERMO: PRELIMINARY DATA

Background: The incidence of psychotic disorders varies in different geographical areas (McGrath 2004). Recent data suggest that the incidence is higher in males, migrant minorities and in urban areas. There aren’t many available epidemiological data on the incidence of psychotic disorders in Italy. This is the first incidence study on psychotic disorders carried out in Palermo, the capital of Sicily. Methods: we screened all patients presenting with their first episode of psychosis to the mental health services of our catchment area (5 inpatient, 5 outpatient units and 3 private psychiatric hospitals) over a period of three years (2008-2011). The diagnosis of psychosis was defined using the Schedules for Clinical Assessment in Neuropsychiatry (SCAN Wing, J. K., et al., 1990).The main socio-demographic data were collected using the MRC Social Data Schedule. When subjects were not available (did not consent) for interview, information was collected from clinical notes. The population at risk referred to the people aged from 18-65 who were resident in the same catchment area (Palermo Municipality) in the period considered, according to the data of the Statistic Office of Palermo Municipality). Results: we identified 216 patients affected by a first episode of psychosis (FEP): 135 M (62.5%) and 81 F (37.5%), mean age 31.42 years (SD: 11.44). 77.1% of FEP had a diagnosis of non affective psychosis, 12.8% of affective psychosis and 10.1% received a diagnosis of other psychosis. 204 subjects were Caucasian, 12 non Caucasian belonging to various ethnicities and they were all first generation migrants (4 Indian, 3 African, 2 Bangladeshi, and 3 Mixed). Population at risk is 425.194 people. The mean age of onset was lower in men than women M: 29.98 years (SD: 10.41) vs. F: 34.28 (SD:12.64) (p=0.013)The incidence of psychotic disorders in our catchment area is 16,9 per 100.000 person years. It was higher in men 21,9 per 100.000 than women 12,2 per 100.000. Discussion: Our study is the first epidemiological study in Sicily investigating the incidence of psychotic disorders. In our population men have a higher incidence of psychotic disorders than women and an earlier age of onset.

Neurodevelopmental Outcomes of Preterm Birth: Contents

Part I. Introduction: 1. Epidemiology of preterm birth Sven Cnattigius and Stefan Johansson 2. The changing face of intensive care for preterm newborns John Wyatt 3. Clinical outcome: neurological sequelae following preterm birth Ingeborg Krageloh-Mann Part II. Neuroimaging: 4. Imaging the preterm brain Terrie E. Inder, Russell Lawrence and Jeffrey J. Neil 5. Structural Magnetic Resonance Imaging Richard W. I. Cooke 6. Magnetic Resonance Imaging findings from adolescence to adulthood Matthew Allin and Muriel Walshe 7. Functional neuroimaging following very preterm birth Chiara Nosarti and Larry Rifkin 8. Diffusion tensor imaging findings in preterm and low birth weight populations Matthew Allin Part III. Behavioural Outcome: 9. Behavioural outcome of preterm birth in childhood and adolescence Elaine Healy 10. Preterm birth and fetal growth in relation to adult psychopathology Christina M. Hultman and Chiara Nosarti Part IV. Neuropsychological Outcome: 11. Cognitive and functional outcomes of children born preterm Betty Vohr 12. Methodological considerations in neurodevelopmental outcome studies of infants born prematurely Glen P. Aylward 13. Language function after preterm birth Teresa M. Rushe 14. A cognitive neuroscience perspective on the development of memory in children born preterm Michelle De Haan 15. Executive function development in preterm children Peter John Anderson, Kelly Howard and Lex W. Doyle Part V. Applied Research: 16. Academic performance and learning disabilities H. Gerry Taylor 17. Pathways of risk and resiliency after prematurity: role of socioeconomical status Michael M. Msall, Mary C. Sullivan and Jennifer Park 18. Cognitive and behavioural interventions Marie C. McCormick and Beth Marie McManus Part VI. Conclusions: 19. Integrative summary and future directions Chiara Nosarti, Robin M. Murray and Maureen Hack.

Neurodevelopmental Outcomes of Preterm Birth: Frontmatter

Part I. Introduction: 1. Epidemiology of preterm birth Sven Cnattigius and Stefan Johansson 2. The changing face of intensive care for preterm newborns John Wyatt 3. Clinical outcome: neurological sequelae following preterm birth Ingeborg Krageloh-Mann Part II. Neuroimaging: 4. Imaging the preterm brain Terrie E. Inder, Russell Lawrence and Jeffrey J. Neil 5. Structural Magnetic Resonance Imaging Richard W. I. Cooke 6. Magnetic Resonance Imaging findings from adolescence to adulthood Matthew Allin and Muriel Walshe 7. Functional neuroimaging following very preterm birth Chiara Nosarti and Larry Rifkin 8. Diffusion tensor imaging findings in preterm and low birth weight populations Matthew Allin Part III. Behavioural Outcome: 9. Behavioural outcome of preterm birth in childhood and adolescence Elaine Healy 10. Preterm birth and fetal growth in relation to adult psychopathology Christina M. Hultman and Chiara Nosarti Part IV. Neuropsychological Outcome: 11. Cognitive and functional outcomes of children born preterm Betty Vohr 12. Methodological considerations in neurodevelopmental outcome studies of infants born prematurely Glen P. Aylward 13. Language function after preterm birth Teresa M. Rushe 14. A cognitive neuroscience perspective on the development of memory in children born preterm Michelle De Haan 15. Executive function development in preterm children Peter John Anderson, Kelly Howard and Lex W. Doyle Part V. Applied Research: 16. Academic performance and learning disabilities H. Gerry Taylor 17. Pathways of risk and resiliency after prematurity: role of socioeconomical status Michael M. Msall, Mary C. Sullivan and Jennifer Park 18. Cognitive and behavioural interventions Marie C. McCormick and Beth Marie McManus Part VI. Conclusions: 19. Integrative summary and future directions Chiara Nosarti, Robin M. Murray and Maureen Hack.

Neurodevelopmental Outcomes of Preterm Birth: Index

Part I. Introduction: 1. Epidemiology of preterm birth Sven Cnattigius and Stefan Johansson 2. The changing face of intensive care for preterm newborns John Wyatt 3. Clinical outcome: neurological sequelae following preterm birth Ingeborg Krageloh-Mann Part II. Neuroimaging: 4. Imaging the preterm brain Terrie E. Inder, Russell Lawrence and Jeffrey J. Neil 5. Structural Magnetic Resonance Imaging Richard W. I. Cooke 6. Magnetic Resonance Imaging findings from adolescence to adulthood Matthew Allin and Muriel Walshe 7. Functional neuroimaging following very preterm birth Chiara Nosarti and Larry Rifkin 8. Diffusion tensor imaging findings in preterm and low birth weight populations Matthew Allin Part III. Behavioural Outcome: 9. Behavioural outcome of preterm birth in childhood and adolescence Elaine Healy 10. Preterm birth and fetal growth in relation to adult psychopathology Christina M. Hultman and Chiara Nosarti Part IV. Neuropsychological Outcome: 11. Cognitive and functional outcomes of children born preterm Betty Vohr 12. Methodological considerations in neurodevelopmental outcome studies of infants born prematurely Glen P. Aylward 13. Language function after preterm birth Teresa M. Rushe 14. A cognitive neuroscience perspective on the development of memory in children born preterm Michelle De Haan 15. Executive function development in preterm children Peter John Anderson, Kelly Howard and Lex W. Doyle Part V. Applied Research: 16. Academic performance and learning disabilities H. Gerry Taylor 17. Pathways of risk and resiliency after prematurity: role of socioeconomical status Michael M. Msall, Mary C. Sullivan and Jennifer Park 18. Cognitive and behavioural interventions Marie C. McCormick and Beth Marie McManus Part VI. Conclusions: 19. Integrative summary and future directions Chiara Nosarti, Robin M. Murray and Maureen Hack.

Neurodevelopmental Outcomes of Preterm Birth: Neurodevelopmental Outcomes of Preterm Birth

Part I. Introduction: 1. Epidemiology of preterm birth Sven Cnattigius and Stefan Johansson 2. The changing face of intensive care for preterm newborns John Wyatt 3. Clinical outcome: neurological sequelae following preterm birth Ingeborg Krageloh-Mann Part II. Neuroimaging: 4. Imaging the preterm brain Terrie E. Inder, Russell Lawrence and Jeffrey J. Neil 5. Structural Magnetic Resonance Imaging Richard W. I. Cooke 6. Magnetic Resonance Imaging findings from adolescence to adulthood Matthew Allin and Muriel Walshe 7. Functional neuroimaging following very preterm birth Chiara Nosarti and Larry Rifkin 8. Diffusion tensor imaging findings in preterm and low birth weight populations Matthew Allin Part III. Behavioural Outcome: 9. Behavioural outcome of preterm birth in childhood and adolescence Elaine Healy 10. Preterm birth and fetal growth in relation to adult psychopathology Christina M. Hultman and Chiara Nosarti Part IV. Neuropsychological Outcome: 11. Cognitive and functional outcomes of children born preterm Betty Vohr 12. Methodological considerations in neurodevelopmental outcome studies of infants born prematurely Glen P. Aylward 13. Language function after preterm birth Teresa M. Rushe 14. A cognitive neuroscience perspective on the development of memory in children born preterm Michelle De Haan 15. Executive function development in preterm children Peter John Anderson, Kelly Howard and Lex W. Doyle Part V. Applied Research: 16. Academic performance and learning disabilities H. Gerry Taylor 17. Pathways of risk and resiliency after prematurity: role of socioeconomical status Michael M. Msall, Mary C. Sullivan and Jennifer Park 18. Cognitive and behavioural interventions Marie C. McCormick and Beth Marie McManus Part VI. Conclusions: 19. Integrative summary and future directions Chiara Nosarti, Robin M. Murray and Maureen Hack.

Neurodevelopmental Outcomes of Preterm Birth: Behavioral outcome

Part I. Introduction: 1. Epidemiology of preterm birth Sven Cnattigius and Stefan Johansson 2. The changing face of intensive care for preterm newborns John Wyatt 3. Clinical outcome: neurological sequelae following preterm birth Ingeborg Krageloh-Mann Part II. Neuroimaging: 4. Imaging the preterm brain Terrie E. Inder, Russell Lawrence and Jeffrey J. Neil 5. Structural Magnetic Resonance Imaging Richard W. I. Cooke 6. Magnetic Resonance Imaging findings from adolescence to adulthood Matthew Allin and Muriel Walshe 7. Functional neuroimaging following very preterm birth Chiara Nosarti and Larry Rifkin 8. Diffusion tensor imaging findings in preterm and low birth weight populations Matthew Allin Part III. Behavioural Outcome: 9. Behavioural outcome of preterm birth in childhood and adolescence Elaine Healy 10. Preterm birth and fetal growth in relation to adult psychopathology Christina M. Hultman and Chiara Nosarti Part IV. Neuropsychological Outcome: 11. Cognitive and functional outcomes of children born preterm Betty Vohr 12. Methodological considerations in neurodevelopmental outcome studies of infants born prematurely Glen P. Aylward 13. Language function after preterm birth Teresa M. Rushe 14. A cognitive neuroscience perspective on the development of memory in children born preterm Michelle De Haan 15. Executive function development in preterm children Peter John Anderson, Kelly Howard and Lex W. Doyle Part V. Applied Research: 16. Academic performance and learning disabilities H. Gerry Taylor 17. Pathways of risk and resiliency after prematurity: role of socioeconomical status Michael M. Msall, Mary C. Sullivan and Jennifer Park 18. Cognitive and behavioural interventions Marie C. McCormick and Beth Marie McManus Part VI. Conclusions: 19. Integrative summary and future directions Chiara Nosarti, Robin M. Murray and Maureen Hack.