Robyn Box

Physiotherapy After Breast Cancer Surgery: Results of a Randomised Controlled Study to Minimise Lymphoedema

The development of secondary arm lymphoedema after the removal of axillary lymph nodes remains a potential problem for women with breast cancer. This study investigated the incidence of arm lymphoedema following axillary dissection to determine the effect of prospective monitoring and early physiotherapy intervention. Sixty-five women were randomly assigned to either the treatment (TG) or control group (CG) and assessments were made preoperatively, at day 5 and at 1, 3, 6, 12 and 24 months postoperatively. Three measurements were used for the detection of arm lymphoedema: arm circumferences (CIRC), arm volume (VOL) and multi-frequency bioimpedance (MFBIA). Clinically significant lymphoedema was confirmed by an increase of at least 200 ml from the preoperative difference between the two arms. Using this definition, the incidence of lymphoedema at 24 mo. was 21%, with a rate of 11% in the TG compared to 30% in the CG. The CIRC or MFBIA methods failed to detect lymphoedema in up to 50% of women who demonstrated an increase of at least 200 ml in the VOL of the operated arm compared to the unoperated arm. The physiotherapy intervention programme for the TG women included principles for lymphoedema risk minimisation and early management of this condition when it was identified. These strategies appear to reduce the development of secondary lymphoedema and alter its progression in comparison to the CG women. Monitoring of these women is continuing and will determine if these benefits are maintained over a longer period for women with early lymphoedema after breast cancer surgery.

Shoulder Movement After Breast Cancer Surgery: Results of a Randomised Controlled Study of Postoperative Physiotherapy

Breast screening programmes have facilitated more conservative approaches to the surgical and radiotherapy management of women diagnosed with breast cancer. This study investigated changes in shoulder movement after surgery for primary, operable breast cancer to determine the effect of elective physiotherapy intervention. Sixty-five women were randomly assigned to either the treatment (TG) or control group (CG) and assessments were completed preoperatively, at day 5 and at 1 month, 3, 6, 12 and 24 months postoperatively. The CG only received an exercise instruction booklet in comparison to the TG who received the Physiotherapy Management Care Plan (PMCP). Analyses of variance revealed that abduction returned to preoperative levels more quickly in the TG than in the CG. The TG women had 14° more abduction at 3 months and 7° at 24 months. Functional recovery at 1 month was greater in those randomised to the TG, with a dominant operated arm (OA) or receiving breast-conserving surgery. However, it was not possible to predict recovery over the 2 years postoperatively on the basis of an individual womans recovery at 1 month postoperatively. The eventual recovery of abduction or flexion range of movement was not related to the dominance of the OA nor to the surgical procedure performed. The PMCP provided in the early postoperative period is effective in facilitating and maintaining the recovery of shoulder movement over the first 2 years after breast cancer surgery.

Neonatal respiratory therapy in the new millennium: Does clinical practice reflect scientific evidence?

Respiratory therapy has historically been considered the primary role of the physiotherapist in neonatal intensive care in Australia. In 2001 a survey was undertaken of all level three neonatal intensive care units in Australia to determine the role of the physiotherapist and of respiratory therapy in clinical practice. It appears that respiratory therapy is provided infrequently, with the number of infants treated per month ranging from 0 to 10 in 15 of the 20 units who provide respiratory therapy, regardless of therapist availability. The median number of respiratory treatments per month during the week was three, and on weekends it was one. Respiratory therapy was carried out by physiotherapists and nurses in 54.6% of units, by physiotherapists only in 36.4% of units, and by nurses only in the remaining 9% of units surveyed. There was also a diminution of the role of respiratory therapy in the extubation of premature infants. A review of the literature shows that overall the use of respiratory therapy reflects current evidence. The question remains whether it is possible to maintain the competency of staff and justify the cost of training in the current healthcare economic climate. It seems probable that the future role of physiotherapists in neonatal intensive care unit may be in the facilitation of optimal neurological development of surviving very low birth weight infants.

Restriction of the range of arm elevation exercises for one week after surgery for breast cancer can reduce the incidence of lymphoedema

Question : Does restriction of full shoulder mobilisation for one week reduce the incidence and severity of lymphoedema in women after axillary lymph node dissection (ALND) for breast cancer? Design : Randomised, controlled trial with concealed allocation and blinded assessment of some outcomes. Setting : Two hospitals in the United Kingdom. Participants : Adult women with early breast cancer admitted for surgery that included axillary lymph node dissection. Previous breast cancer, axillary surgery and local radiotherapy were exclusion criteria. Randomisation of 116 participants allotted 58 to a standard exercise regimen and 58 to the same regimen with restricted arm and shoulder movement for the first week. Interventions : All participants were prescribed four 10-minute exercise sessions per day, in which individual exercises were repeated slowly and rhythmically 3 to 4 times. The exercises included unresisted shoulder and elbow range-of-motion exercises while upright. The early mobilisation group commenced full shoulder mobilisation within two days after surgery. The exercises were modified for the delayed mobilisation group so that the arm was not elevated above horizontal for the first 7 days after surgery. Exercises encouraging full range of shoulder movement were introduced in the second week. The exercises were supervised during the hospital admission and were prescribed to continue for one year at home. Outcome measures : The primary outcome was the incidence of lymphoedema, defined as a 200 ml or greater difference in arm volume compared to the unoperated arm. Secondary outcome measures were the severity of lymphoedema again determined by volume, wound drainage volumes, range of shoulder motion, grip strength, and quality of life scores related to shoulder disability and breast cancer therapy. Results : 109 participants completed the study. After one year, 16 women in the early mobilisation group but only 6 women in the delayed mobilisation group had developed lymphoedema. Thus one case of lymphoedema was prevented for every 6 women managed with the exercise regimen that delayed shoulder mobilisation (95% CI 3 to 35). Lymphoedema severity and wound drainage were both significantly greater in the early mobilisation group. The groups did not differ significantly on the remaining secondary outcomes. Conclusion : The incidence of lymphoedema can be reduced by restricting exercises so that the arm is not elevated above horizontal for one week after ALND.

Compression use during an exercise intervention and associated changes in breast cancer-related lymphedema.

This study assessed the association between compression use and changes in lymphedema observed in women with breast cancer–related lymphedema who completed a 12‐week exercise intervention.

Exercise barriers self-efficacy: development and validation of a subcale for individuals with cancer-related lymphedema

BackgroundNo tool exists to measure self-efficacy for overcoming lymphedema-related exercise barriers in individuals with cancer-related lymphedema. However, an existing scale measures confidence to overcome general exercise barriers in cancer survivors. Therefore, the purpose of this study was to develop, validate and assess the reliability of a subscale, to be used in conjunction with the general barriers scale, for determining exercise barriers self-efficacy in individuals facing lymphedema-related exercise barriers.MethodsA lymphedema-specific exercise barriers self-efficacy subscale was developed and validated using a cohort of 106 cancer survivors with cancer-related lymphedema, from Brisbane, Australia. An initial ten-item lymphedema-specific barrier subscale was developed and tested, with participant feedback and principal components analysis results used to guide development of the final version. Validity and test-retest reliability analyses were conducted on the final subscale.ResultsThe final lymphedema-specific subscale contained five items. Principal components analysis revealed these items loaded highly (>0.75) on a separate factor when tested with a well-established nine-item general barriers scale. The final five-item subscale demonstrated good construct and criterion validity, high internal consistency (Cronbach’s alpha = 0.93) and test-retest reliability (ICC = 0.67, p < 0.01).ConclusionsA valid and reliable lymphedema-specific subscale has been developed to assess exercise barriers self-efficacy in individuals with cancer-related lymphedema. This scale can be used in conjunction with an existing general exercise barriers scale to enhance exercise adherence in this understudied patient group.

Normative Interlimb Impedance Ratios: Implications for Early Diagnosis of Uni- and Bilateral, Upper and Lower Limb Lymphedema

BACKGROUND Bioimpedance spectroscopy detects unilateral lymphedema if the ratio of extracellular fluid (ECF) between arms or between legs is outside three standard deviations (SDs) of the normative mean. Detection of bilateral lymphedema, common after bilateral breast or gynecological cancer, is complicated by the unavailability of an unaffected contralateral limb. The objectives of this work were to (1) present normative values for interarm, interleg, and arm-to-leg impedance ratios of ECF and ECF normalized to intracellular fluid (ECF/ICF); (2) evaluate the influence of sex, age, and body mass index on ratios; and (3) describe the normal change in ratios within healthy individuals over time. METHODS Data from five studies were combined to generate a normative data set (n = 808) from which mean and SD were calculated for interarm, interleg, and arm-to-leg ratios of ECF and ECF/ICF. The influence of sex, age, and body mass index was evaluated using multiple linear regression, and normative change was calculated for participants with repeated measures by subtracting their lowest ratio from their highest ratio. RESULTS Mean (SD) interarm, interleg, dominant arm-to-leg, and nondominant arm-to-leg ratios were 0.987 (0.067), 1.005 (0.072), 1.129 (0.160), and 1.165 (0.174) for ECF ratios; and 0.957 (0.188), 1.024 (0.183), 1.194 (0.453), and 1.117 (0.367) for ECF/ICF ratios, respectively. Arm-to-leg ratios were significantly affected by sex, age, and body mass index. Mean normative change ranged from 7.2% to 14.7% for ECF ratios and from 14.7% to 67.1% for ECF/ICF ratios. CONCLUSION These findings provide the necessary platform for extending bioimpedance-based screening beyond unilateral lymphedema.

The motor performance of preschool-aged children after surgery for congenital heart disease.

This study compared the motor performance of preschool-aged children who had undergone surgery for congenital heart disease with that of a group of children matched for age, sex, preschool experience, racial and socio-economic background. Analysis of the results indicated that the performances of the children with congenital heart disease were significantly immature compared to the performances of the control children on the total assessment and in the areas of gross motor, muscle strength, fine motor, tone and postural reactions. Sex, age at first surgical intervention and presence of a cyanotic heart defect did not influence the performances of the study group children. Age at assessment and socio-economic background were found to influence motor performances. The need for physiotherapists to be involved in the follow-up of children with congenital heart disease is supported.