Rodrigo Martins

Molluscicidal activity of 2-hydroxy-[1,4]naphthoquinone and derivatives

The toxic profile of lawsone (2-hydroxy-[1,4]naphthoquinone) and a series of [1,4]naphthoquinone derivatives was evaluated against the brine shrimp Artemia salina and against the mollusk Biomphalaria glabrata, the main transmitting vector of schistosomiasis in Brazil. Of the seventeen compounds tested nine fell below the threshold of 100 microg/mL set for potential molluscicidal activity by the World Health Organization. As a general rule derivatives with non-polar substituents presented the highest molluscicidal activities. These substances showed significant toxicity in A. salina lethality bioassay.

Composition and Molluscicidal Properties of Essential Oils from Leaves of Xylopia langsdorffiana A. St. Hil. et Tul. (Annonaceae)

Abstract The volatile fraction of Xylopia langsdorffiana leaves was analyzed by GC and GC/M S and tested for molluscicidal activity. With this methodology 19 different components were identified in the oil. Among them, germacrene D (22.9%), trans-β-guaiene (22.6%), β-caryophyllene (15.7%), and α-pinene (7.3%) were found to be the major constituents. The oil showed significant molluscicidal activity against Biomphalaria glabrata, with an LC90 value of 5.6 μg/mL, which falls below the threshold of 100 μg/mL, set for potential molluscicidal activity by the World Health Organization.

Molluscicidal activities of six species of Bignoniaceae from north–eastern Brazil, as measured against Biomphalaria glabrata under laboratory conditions

Abstract The molluscicidal profile and brine-shrimp bio-activity of the ethanolic extracts of plants from the Bignoniaceae family were determined. The six extracts investigated were of the stems of Melloa quadrivalvis and Tabebuia aurea, and whole plants of Adenocalymma comosum, Arrabidaea parviflora, Cuspidaria argentea and Clytostoma binatum. When tested in the laboratory, with Biomphalaria glabrata as the test snail, all six extracts gave median lethal concentrations (9–54 μg/ml) that fell well below the upper threshold, of 100 μg/ml, set for a potential molluscicide by the World Health Organization.

Composition and molluscicidal activity of the essential oil from the stem bark of Ocotea bracteosa (meisn.) mez

Abstract The volatile oil of Ocotea bracteosa (Meisn.) Mez. stem bark was analyzed by GC and GC/MS and tested for molluscicidal activity on Biomphalaria glabrata. Twenty compounds were identified corresponding to about 70% of the oil. The major constituents were δ-cadinene (12.4%), ledene (11.1%), and globulol (10.1%). The oil showed significant molluscicidal activity against Biomphalaria glabrata, with an LC90 value of 8.3 μg/mL, which falls below the threshold of 100 μg/mL, set for potential molluscicidal activity by the World Health Organization.