Ronald J. Ferguson
University of Florida
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Featured researches published by Ronald J. Ferguson.
Journal of Maternal-fetal & Neonatal Medicine | 2006
Rodney K. Edwards; Ronald J. Ferguson; Leticia Reyes; Mary B. Brown; Douglas W. Theriaque; Patrick Duff
Objective. To determine if the likelihood of preterm delivery is more dependent on the specific organisms present in the vagina than on the presence of bacterial vaginosis. Methods. We evaluated the vaginal fluid of a prospective cohort of women at 23–32 weeks of gestation with signs and symptoms of preterm labor and intact membranes. Forward stepwise logistic regression models were used to evaluate the relationship between preterm delivery and the presence of anaerobic bacteria, Gardnerella, ureaplasmas and mycoplasmas, and sialidase. Results. The cohort included 137 women, and complete delivery information was available for 134 of them. The rate of preterm delivery was 28% (37 of 134). Mycoplasma genitalium independently was associated with spontaneous preterm delivery (OR 3.48; 95% CI 1.41, 8.57). After controlling for this factor, none of the other variables were significantly prognostic for spontaneous preterm delivery (residual overall p = 0.19). Conclusion. The presence of Mycoplasma genitalium in the vagina of pregnant women is an independent risk factor for spontaneous preterm delivery.
American Journal of Reproductive Immunology | 2006
Rodney K. Edwards; Ronald J. Ferguson; Patrick Duff
Problem To determine the associations between preterm delivery <37 weeks (PTD), cervical fluid interleukin‐1β (IL‐1β) concentration, and its +3953 single nucleotide polymorphism (SNP).
Biology of Blood and Marrow Transplantation | 2013
Michael J. Haller; Clive Wasserfall; Maigan A. Hulme; Miriam Cintron; Todd M. Brusko; Keiran M. McGrail; John R. Wingard; Douglas W. Theriaque; Jonathan J. Shuster; Ronald J. Ferguson; Marianne Kozuch; Michael Clare-Salzler; Mark A. Atkinson; Desmond A. Schatz
We sought to determine if autologous umbilical cord blood (UCB) infusion followed by 1 year of supplementation with vitamin D and docosahexaenoic acid (DHA) can preserve C-peptide in children with type 1 diabetes. We conducted an open-label, 2:1 randomized study in which 15 type 1 diabetes subjects with stimulated C-peptide > .2 pmol/mL received either (1) autologous UCB infusion, 1 year of daily oral vitamin D (2000 IU), and DHA (38 mg/kg) and intensive diabetes management or (2) intensive diabetes management alone. Primary analyses were performed 1 year after UCB infusion. Treated (N = 10) and control (N = 5) subjects had median ages of 7.2 and 6.6 years, respectively. No severe adverse events were observed. Although the absolute rate of C-peptide decline was slower in treated versus control subjects, intergroup comparisons failed to reach significance (P = .29). Area under the curve C-peptide declined and insulin use increased in both groups (P < .01). Vitamin D levels remained stable in treated subjects but declined in control subjects (P = .01). DHA levels rose in treated subjects versus control subjects (P = .003). CD4/CD8 ratio remained stable in treated subjects but declined in control subjects (P = .03). No changes were seen in regulatory T cell frequency, total CD4 counts, or autoantibody titers. Autologous UCB infusion followed by daily supplementation with vitamin D and DHA was safe but failed to preserve C-peptide. Lack of significance may reflect small sample size. Future efforts will require expansion of specific immunoregulatory cell subsets, optimization of combined immunoregulatory and anti-inflammatory agents, and larger study cohorts.
Journal of Pharmacology and Experimental Therapeutics | 1998
Ronald J. Ferguson; Sonia M. de Morais; Simone Benhamou; Christine Bouchardy; Joyce Blaisdell; Gordon C. Ibeanu; Grant R. Wilkinson; Troy C. Sarich; James M Wright; Pierre Dayer; Joyce A. Goldstein
Journal of Pharmacology and Experimental Therapeutics | 1999
Gordon C. Ibeanu; Joyce Blaisdell; Ronald J. Ferguson; Burhan I. Ghanayem; Kim Brøsen; Simone Benhamou; Christine Bouchardy; Grant R. Wilkinson; Pierre Dayer; Joyce A. Goldstein
General and Comparative Endocrinology | 2001
Nancy D. Denslow; Christopher J. Bowman; Ronald J. Ferguson; H.Stephen Lee; Michael J. Hemmer; Leroy C. Folmar
American Journal of Obstetrics and Gynecology | 2005
Whitney Jamie; Rodney K. Edwards; Ronald J. Ferguson; Patrick Duff
Archive | 1999
Nancy D. Denslow; Christopher J. Bowman; G Robinson; Hs Lee; Ronald J. Ferguson; Michael J. Hemmer; Leroy C. Folmar
American Journal of Obstetrics and Gynecology | 2005
Rodney K. Edwards; Ronald J. Ferguson; Jonathan J. Shuster; Douglas W. Theriaque; Susan Gentry; Patrick Duff
/data/revues/00029378/v189i6sS/S0002937803012316/ | 2011
Rodney K. Edwards; Ronald J. Ferguson; Susan Gentry; Jonathan J. Shuster; Patrick Duff