Rosa Zabala
University of the Basque Country
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Featured researches published by Rosa Zabala.
American Journal of Roentgenology | 2007
José Luis del Cura; Iñaki Torre; Rosa Zabala; Ana Legórburu; del Cura Jl; Zabala R
OBJECTIVE The purpose of our study was to evaluate the short- and long-term effectiveness of sonographically guided percutaneous needle aspiration and lavage in calcific tendinitis of the shoulder and to study the progress of calcifications and symptoms in the first year after treatment. MATERIALS AND METHODS Symptoms and radiologic findings after percutaneous aspiration of calcific tendinitis were prospectively evaluated in the short and the long term using a shoulder pain and disability index, evaluation of shoulder motion, and a survey of the self-perception by the patients regarding the progress of their disease. RESULTS Sixty-seven consecutive shoulders were treated. A significant improvement was seen in shoulder motion, pain, and disability in the short term and in the long term (p < 0.0001). One year after treatment, 91% of shoulders had substantially or completely improved, 64% had perfect motion, and calcifications on radiography had resolved completely or nearly completely in 89%. A transitory recurrence was observed approximately 15 weeks after treatment in 44.3% of shoulders that improved. CONCLUSION Percutaneous needle aspiration and lavage is effective in the short term and in the long term in calcific tendinitis of the shoulder, with results similar to or better than those published for other techniques, and it is only slightly invasive and painful. Progress after treatment may include a transitory period of recurrence of the pain.
European Urology | 2010
José Luis del Cura; Rosa Zabala; Jose I. Iriarte; Miguel Unda
BACKGROUND Radiofrequency ablation (RFA) is a minimally aggressive, therapeutic alternative for renal tumors. It can be an alternative to nephrectomy in patients with previous nephrectomy, bilateral tumors, von Hippel-Lindau disease, or small renal carcinomas and in those with contraindications for surgery. OBJECTIVE To assess the effectiveness of the treatment of renal tumors by RFA in the short and medium term and to identify the possible complications and the factors that determine therapeutic success. DESIGN, SETTING, AND PARTICIPANTS A retrospective review of patients with renal tumors treated with RFA between May 2005 and December 2008 was performed in a tertiary academic hospital. Patients were selected among those with previous nephrectomy, bilateral neoplasms, von Hippel-Lindau disease, surgical risk, comorbidity, advanced age, or patients refusal to surgery. Tumors with evidence of extrarenal extension were excluded. Patients were followed up for 10-50 mo using computed tomography and magnetic resonance imaging. INTERVENTION Ultrasound-guided RFA was performed on 65 tumors (range: 1.2-5.3 cm) of 58 patients using multitined electrodes. MEASUREMENTS Incomplete ablation rate, therapeutic success rate, and complications rate. RESULTS AND LIMITATIONS Therapeutic success was achieved in 59 of 65 tumors (91%): 53 in a single session, 5 in two sessions, and 1 in three sessions. A significant relationship was observed between size and growth pattern of the tumor and both therapeutic success and incomplete ablation rates. Therapeutic success in tumors >5 cm was 60%. Complications were detected in 10 patients (13%); 5% were considered major complications. Limitations include the lack of pathologic studies to confirm a complete ablation and the lack of a control group to compare with the results of those who underwent nephrectomy. CONCLUSIONS RFA is safe and effective in renal tumors. Corticomedullary lesions and tumors >3 cm have greater possibility of incomplete ablation. In tumors >5 cm, RFA has a significant failure rate.
Apmis | 2005
José I. López; José Luis del Cura; Rosa Zabala; Francisco J. Bilbao
Ultrasound‐guided needle biopsy is a safe and efficient diagnostic method increasingly used in the initial approach to superficial and deep musculoskeletal tumours. However, so far no general consensus has been reached regarding its reliability. During a 6‐year period (1999–2004), biopsies were taken from 188 patients (100 females, 88 males; age average 55.8 years) with musculoskeletal tumours under ultrasound guidance using 18G BioPince® or 14G ProMag® 2.2 true‐cut type needles. Cytological (imprints and cytocentrifugates) and histological material was obtained for diagnosis in every case. The lower extremity (59 cases) and the abdominal wall (29 cases) were the most commonly affected sites. Benign/reactive tumours (77 cases), metastatic epithelial malignancies (40 cases), and sarcomas (36 cases) were most frequently diagnosed. In 180 (95.75%) cases, core needle results were concordant with the definitive diagnosis (97 true positives and 83 true negatives). Relevant diagnostic discordance was seen in 8 (4.25%) cases (8 false negatives and 0 false positives). Sensitivity, specificity and positive and negative predictive values were 92%, 100%, 100%, and 91%, respectively. Ultrasound‐guided core biopsy is thus a useful method in the initial approach to musculoskeletal tumours that allows correct patient management in the vast majority of cases.
Apmis | 2006
José I. López; José Luis del Cura; Aitor Fernández de Larrinoa; Olatz Gorriño; Rosa Zabala; Francisco J. Bilbao
Core biopsy has not traditionally been recommended in the study of spleen nodules due to the supposed fragility of this organ leading to a high risk of post‐core biopsy complications. A total of 13 patients who presented solid spleen nodules, diffuse splenomegaly, or both on imaging studies (CT, MR, US) were biopsied under ultrasound control with 18G BioPince® needles. Cytological (imprints and cytocentrifugates) and histological material were obtained for diagnosis in every case. Malignant lymphomas were the most commonly found pathology (four diffuse large B‐cell lymphomas, two follicular lymphomas, one Hodgkins disease, one B‐cell lymphoma, NOS). In addition, there was one littoral‐cell angioma, one well‐differentiated neuroendocrine carcinoma, metastatic, and one haemangioma. The remaining two cases showed congestive features, and supposed spleen involvement by lymphoma in one of them was ruled out. On follow up, there were no complications related to the core biopsy. Splenectomy was performed in six cases, two diagnostic and four therapeutic. We conclude that core biopsy is a safe and efficient method in the diagnosis of spleen nodules that could be considered in the routine diagnostic algorithm of these lesions.
Revista Española de Patología | 2006
José I. López; Aitor Fernández de Larrinoa; Rosa Zabala; Laura Oleaga; José Luis del Cura; Francisco J. Bilbao
Resumen Antecedentes La biopsia guiada por control ecografico esta siendo utilizada de manera creciente en los ultimos anos como aproximacion diagnostica inicial en los tumores renales, aunque su aceptacion entre radiologos y patologos aun no es generalizada. Metodos Durante un periodo de 6 anos (2000-2005), se han biopsiado por este metodo y con agujas 18G un total de 48 tumores renales en 47 pacientes. Resultados Se observo un predominio de varones (34V/13M) y la edad promedio se situo en 51,7 anos (rango 1-92). Treinta y siete (77,1%) casos correspondieron a neoplasias, incluyendo adenocarcinomas renales (25 casos), oncocitomas (3 casos), linfomas (3 casos), tumores de Wilms (2 casos), un tumor carcinoide metastasico, un carcinoma epidermoide metastatico, un nefroma quistico y un sarcoma fusocelular. Cinco casos (10,4%) correspondieron a pseudotumores (3 quistes renales y 2 pielonefritis cronicas). La biopsia proporciono tejido renal normal en 4 casos y tejido fibroadiposo en 2. Se detectaron minimas discrepancias en la adjudicacion de la variante histologica del cancer en 2 casos. Conclusiones La biopsia cilindro guiada por ecografia es un metodo muy util y fiable para el diagnostico de los tumores renales, y deberia ser incluida como herramienta de primera linea en su manejo. Sin embargo, para la obtencion de optimos resultados que puedan llevar a un tratamiento individualizado, se precisa una estrecha colaboracion entre clinicos, radiologos y patologos.
European thyroid journal | 2012
José I. López; Rosa Zabala; José Luis del Cura
Background: Thyroid core biopsies obtained with ultrasound (US)-guided needles are an alternative to conventional fine-needle aspiration and, according to various authors, have greater sensitivity and specificity. The technique is inexpensive, rapid and reliable with a low rate of complications, similar to conventional fine-needle aspiration procedures. Objectives: This paper critically reviews the methodology for obtaining samples and processing them in the pathology laboratory. Methods: Accumulated experience with 1,065 cases of US-guided core biopsy of the thyroid gland in a 15-year period. Results: US-guided core biopsy is a useful, inexpensive and safe method in the histological diagnosis of thyroid gland pathology. Thyroid samples obtained this way are not a substitute for fine-needle aspiration cytology. Indeed, some authors assert that the best results are obtained by combining the two approaches, the methods being complementary. Conclusions: To take best advantage of the findings from these techniques, pathologists must know which types of diagnoses can be made and the fundamentals of how and, lastly, what cannot be diagnosed and the reasons why. Best results are obtained with a multidisciplinary approach in a hospital committee composed of endocrinologists, surgeons, radiologists and pathologists, who analyse and provide a background on each case.
Radiología | 2010
J.L. del Cura; Rosa Zabala; I. Corta
Ultrasonography is the most appropriate tool for interventional procedures in the musculoskeletal system when the lesion is visible on ultrasonography. Procedures performed under ultrasonographic guidance include: taking biopsies; draining abscesses; bursitis; hematomas or muscle tears; treating cystic lesions; diagnostic or therapeutic arthrocentesis; injecting substances into joints or lesions; aspirating calcium deposits and extracting foreign bodies. Although some of these procedures are often carried out without imaging guidance, ultrasonographic guidance improves their efficacy. Drainage can be performed with catheters or needles and makes it possible to avoid more aggressive treatments in most cases. Urokinase is useful for draining hematomas or fibrinous collections. Injecting corticoids is useful in the treatment of synovial cysts, Bakers cyst, tendinitis, and non-infective arthritis. Calcifying tendinitis of the shoulder can be treated effectively with percutaneous calcium lavage.
Radiología | 2010
J.L. del Cura; Rosa Zabala; I. Corta
Ultrasound (US) has important advantages in guiding interventional procedures: it is cheap and widely available, it does not use ionizing radiation, and it takes less time than other techniques. US guidance can be carried out using devices adapted to probes or using the freehand technique (holding the needle in one hand and the probe in the other). US-guided procedures require careful planning, adequate hemostasis (or a compressible puncture site), patient’s informed consent, and appropriate measures to ensure asepsis and anesthesia. The technique consists in introducing the needle or catheter following the plane of the US. The progression of the needle is controlled in real time. High resolution linear probes are ideal for interventional procedures in superfi cial tissues, but 3.5 MHz probes are required for procedures in deep tissues. The most common procedures include biopsies, drainages, and percutaneous injections. Biopsies can be carried out using fine needles to obtain material for cytological study (fine-needle aspiration cytology) or using large needles to obtain specimens for histologic study (core biopsy). Core biopsy is more sensitive and more specifi c, and it has a low rate of complications. Drainage almost always involves placing a catheter in a fl uid collection; it can be performed using the Seldinger technique, trocars, or pleural catheters. US-guided percutaneous injections are intended to inject substances into infectious lesions, tumors, or nerve plexuses, and they are especially useful in musculoskeletal disease.
Radiología | 2010
J.L. del Cura; Rosa Zabala; I. Corta
Ultrasonography is the most appropriate tool for interventional procedures in the musculoskeletal system when the lesion is visible on ultrasonography. Procedures performed under ultrasonographic guidance include: taking biopsies; draining abscesses; bursitis; hematomas or muscle tears; treating cystic lesions; diagnostic or therapeutic arthrocentesis; injecting substances into joints or lesions; aspirating calcium deposits and extracting foreign bodies. Although some of these procedures are often carried out without imaging guidance, ultrasonographic guidance improves their efficacy. Drainage can be performed with catheters or needles and makes it possible to avoid more aggressive treatments in most cases. Urokinase is useful for draining hematomas or fibrinous collections. Injecting corticoids is useful in the treatment of synovial cysts, Bakers cyst, tendinitis, and non-infective arthritis. Calcifying tendinitis of the shoulder can be treated effectively with percutaneous calcium lavage.
Revista Española de Patología | 2009
José I. López; Aitor Fernández de Larrinoa; Rosa Zabala; José Luis del Cura
Resumen La biopsia de tiroides obtenida con aguja guiada por control ecografico es una alternativa a la puncion aspiracion con aguja fina que, segun multiples autores, ofrece mayor sensibilidad y especificidad diagnostica que esta. Este trabajo revisa de una manera critica la metodologia de obtencion de la muestra, su manipulacion optima en el Laboratorio de Anatomia Patologica, lo que se puede diagnosticar, como hacerlo, y lo que no, y por que no. El rendimiento optimo de este procedimiento se obtiene en el contexto de un comite multidisciplinario en el que los diversos especialistas implicados discuten los casos complejos.