Rosângela Maria Lopes de Sousa

Importance of lipid accumulation product index as a marker of CVD risk in PCOS women

BackgroundThe polycystic ovary syndrome (PCOS) is considered the most common endocrine disease during the womans reproductive life, with prevalence ranging from 5 to 10 % of women of reproductive age. There is a paucity of studies regarding the use of the lipid accumulation product (LAP) as a risk marker for the development of cardiovascular disease (CVD).MethodsA cross-sectional study was conducted on 78 women aged 18 to 42 years seen at University Hospital of Maranhão, with a diagnosis of polycystic ovary syndrome according to the Rotterdam criteria. The following variables of interest were recorded on a protocol form: sociodemographic and behavioral data, body mass index, waist circumference, fasting glucose, total cholesterol, triglycerides, low density lipoprotein cholesterol, high-density lipoprotein cholesterol, and systolic and diastolic blood pressure.ResultsLogistic regression showed that, except for HDL, all cardiovascular risk markers presented a higher chance of being altered when the lipid accumulation product was above the cut off value of 37.9 cm.mmol/L.ConclusionThe lipid accumulation product seems to be sufficient to indicate a risk of cardiovascular diseases in women with polycystic ovary syndrome.

Depression after CABG: a prospective study

Introduction Depression during or shortly after hospitalization elevated two to three times the risk of mortality or nonfatal cardiac events, significantly increasing the morbidity and mortality of these patients. Objective To assess the impact of revascularization on symptoms of depression in patients with coronary artery disease. Methods A prospective cohort study of 57 patients of both sexes undergoing coronary artery bypass grafting between June 2010 and June 2011. We used the SF-36 to assess quality of life, and the Beck Depression Inventory to detect depressive symptoms, applied preoperatively and six months. Results The prevalence of patients aged 60-69 years was 22 patients (38.60%), 39 men (68.42%), 26 described themselves as mixed race (45.61%), 16 literate (28.07 %) and 30 married (52.63%). The beck depression inventory score demonstrated increased after revascularization: 15 patients mild (26.32%) at time zero to 17 (29.82%) after. And with moderate, seven patients (12.28%) before and 10 (17.54%) after. In the categories of individuals with decreased minimum degree of 32 (56.14%) to 28 (49.12%), and severe of three (5.26%) for two (3.51%) patients. Association was observed between beck depression inventory, gender, age, lifestyle, comorbidities and quality of life. Conclusion There was a high prevalence of elevated beck depression inventory scores, lowest scores of depressive symptoms among men and association between the improvement of quality of life scores and beck depression inventory.

Breast contour detection with shape priors

Breast cancer conservative treatment (BCCT) is considered the gold standard of breast cancer treatment. However, aesthetic results are heterogeneous and difficult to evaluate in a standardised way. The limited reproducibility of subjective aesthetic evaluation in BCCT forced the research on objective methods. A recent computer system was developed to objectively and automatically evaluate the aesthetic result of BCCT. In this system, the detection of the breast contour on the digital photograph of the patient is necessary to extract the features subsequently used in the evaluation process. In this paper we extend an algorithm based on the shortest path on a graph to detect automatically the breast contour. The advantage of graph algorithms is that they are guaranteed to find the global optimum of the problem; the difficulty is that they make it hard to enforce shape constraints. We define and compare different techniques to introduce the a priory knowledge of the mammary contour. Experimental results show that the proposed techniques consistently outperform the base method.

Perfil metabólico em mulheres de diferentes índices de massa corporal com síndrome dos ovários policísticos

PURPOSE: To characterize and compare clinical, anthropometric and biochemical-metabolic variables in patients with polycystic ovary syndrome (PCOS), stratified according to body mass index (BMI). METHODS: A cross-sectional study conducted on 78 women aged 18 to 45 years with a clinical diagnosis of PCOS by the Rotterdam criteria. Patients were stratified according to BMI. The variables analyzed were: age, marital status, physical inactivity, menstrual irregularity, blood pressure (BP), anthropometric measurements, lipid profile, fasting glucose, and hormone measurements. To compare the variables between the different BMI values we used analysis of variance and the Kruskal-Wallis test. The level of significance was set at 5% for all tests. RESULTS: The patients had a mean age of 26.3 years, 79.5% of them were sedentary and 68% had hyperandrogenism. Waist circumference, waist/hip ratio, waist/height ratio and percentage of body fat were higher in the obese group. The markers of cardiovascular risk (CVR - fasting glucose, systolic and diastolic BP and LDL-cholesterol) were directly proportional to BMI, whereas HDL-cholesterol and SHBG were inversely related to BMI. CONCLUSION: The presence of markers of CVR factors increased proportionally to BMI, indicating that the metabolic profile of obese women with PCOS is more unfavorable than that of non-obese patients.

Scored patient-generated Subjective Global Assessment: Length of hospital stay and mortality in cancer patients

1 Universidade Federal do Maranhão, Centro de Ciências Biológicas e da Saúde, Programa de Pós-Graduação em Saúde do Adulto e da Criança. Av. dos Portugueses, 1966, Prédio das Pós-Graduações, Bacanga, 65085-580, São Luís, MA, Brasil. Correspondência para/Correspondence to: AF SANTOS. E-mail: . 2 Universidade Ceuma, Coordenação do Curso de Nutrição. São Luís, MA, Brasil. 3 Faculdade Santa Terezinha, Coordenação do Curso de Nutrição. São Luís, MA, Brasil. 4 Universidade Federal do Maranhão, Centro de Ciências Biológicas e da Saúde, Departamento do Curso de Nutrição. São Luís, MA, Brasil.

Indicadores antropométricos em crianças e adolescentes com doença do refluxo gastroesofágico atendidos em um ambulatório especializado em São Luís, Maranhão, Brasil

Helicobacter pylori is a Gram negative bacterium that cause chronic gastritis, duodenal ulcers and can predispose the gastric cancer. The study aimed to determinate the prevalence of H. pylori infection by different methods of diagnosis in patients submitted to endoscopy. Of the 145 patients included in the study, were collected fragments of gastric mucosa for histological analysis, and for the rapid urease test. The breath test was also performed. The H. pylori infection was detected in 84 (57.9%) patients by histological study, the rapid test of urease was positive in 81 (55,8%) and the breath test in 62 (56,3%). There was no statistically significant difference when comparing the prevalence of infection by different methods of diagnosis. The prevalence of H. pylori infection in our community was lower than that found in the literature for patients with age similar to this study (mean = 53.19 years).