Rudolf Dr. Hanko
Bayer
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Publication
Featured researches published by Rudolf Dr. Hanko.
Analytical Biochemistry | 1990
Paul P. Tamburini; Robert N. Dreyer; Jutta Hansen; Jack Letsinger; Jim Elting; Ann Gore-Willse; Robert Dally; Rudolf Dr. Hanko; David G. Osterman; Michael E. Kamarck; Heeja Yoo-Warren
A rapid sensitive method for the quantification of in vitro HIV-protease activity has been developed on the basis of the endoproteolytic conversion of N-Dns-SQ-NYPIV to N-Dns-SQNY. The use of the N-dansyl group as a fluorescence label was shown to not significantly alter the apparent kinetic parameters for the peptide-enzyme interaction. Using fluorescence detection, the dansylated product and unconverted substrate are detected in a single rapid (3 min) isocratic reverse-phase HPLC separation in quantities as low as 0.2 pmol. The method is highly reproducible and suited to a variety of applications including the analysis of large sample numbers and rigorous enzymological studies.
Archive | 1994
Rüdiger Fischer; Gabriele Bräunlich; Klaus-Helmut Mohrs; Rudolf Dr. Hanko; John-Edward Butler-Ransohoff; Mazen Es-Sayed; Graham Dr Sturton; Steve Tudhope; Trevor Dr Abram; Wendy J Dr Mcdonald-Gibson
Archive | 1995
Trevor Dr Abram; Gabriele Bräunlich; Mazen Es-Sayed; Rüdiger Fischer; Mary F. Fitzgerald; Rudolf Dr. Hanko; Graham Dr Sturton; Stephen Dr Tudhope
Archive | 1992
Matthias Dr. Müller-Gliemann; Martin Dr. Beuck; Stanislav Kazda; Johannes-Peter Stasch; Andreas Dr. Knorr; Stefan Wohlfeil; Walter Dr. Hübsch; Jürgen Dr. Dressel; Peter Fey; Rudolf Dr. Hanko; Thomas Dr. Krämer; Ulrich Dr. Müller; Siegfried Zaiss
Archive | 1995
Gabriele Bräunlich; Rüdiger Fischer; Mazen Es-Sayed; Rudolf Dr. Hanko; Stephen Dr Tudhope; Graham Dr Sturton; Trevor Dr Abram; Wendy J Dr Mcdonald-Gibson; Mary F. Fitzgerald
Archive | 1992
Ulrich Dr. Müller; Klaus Mohrs; Jürgen Dr. Dressel; Rudolf Dr. Hanko; Walter Dr. Hübsch; Michael Matzke; Ulrich Niewohner; Siegfried Raddatz; Thomas Dr. Krämer; Matthias Dr. Müller-Gliemann; Hans-Peter Dr. Bellemann; Martin Dr. Beuck; Stanislav Kazda; Stefan Wohlfeil
Archive | 1995
Trevor Dr Abram; Gabriele Bräunlich; Mazen Es-Sayed; Rüdiger Fischer; Mary F. Fitzgerald; Rudolf Dr. Hanko; Wendy J Dr Mcdonald-Gibson; Graham Dr Sturton; Stephen Dr Tudhope
Archive | 1993
Rudolf Dr. Hanko; Walter Dr. Hübsch; Jürgen Dr. Dressel; Peter Fey; Thomas Dr. Krämer; Ulrich Dr. Müller; Matthias Dr. Müller-Gliemann; Martin Dr. Beuck; Stanislav Kazda; Claudia Hirth-Dietrich; Andreas Knorr; Johannes-Peter Stasch; Stefan Wohlfeil; Özkan Dr. Yalkinoglu
Archive | 1994
Peter Fey; Walter Dr. Hübsch; Jürgen Dr. Dressel; Rudolf Dr. Hanko; Thomas Dr. Krämer; Ulrich Dr. Müller; Matthias Dr. Müller-Gliemann; Martin Dr. Beuck; Hilmar Bischoff; Stefan Wohlfeil; Dirk Denzer; Stanislav Kazda; Johannes-Peter Stasch; Andreas Knorr; Siegfried Zaiss
Archive | 1995
Hanno Wild; Rudolf Dr. Hanko; Michael Dorschug; Hans-Dietrich Dr. Hörlein; Jurgen Beunink; Heiner Apeler; Hermann Wehlmann; Walter Sebald
