若林 攻

2-(N-アシルベンジルアミノ)-4-メチル-6-フルオロアルキル-1,3,5-トリアジン系化合物の光合成電子伝達系阻害活性および除草活性

INTRODUCTION Strong photosynthetic electron transport (PET) inhibitory and herbicidal activities of 2-benzylamino-4-methyl-6trifluoromethyl-1,3,5-triazines have been already reported by Kuboyama et al.1,2) and Inoue et al.3) in our group. They tried molecular modifications on the benzylamino group of the compounds, namely substitution of the benzyl-benzene ring, N-alkylation, elongation of the methylene chain between amino group and benzene ring and absolute configuration of benzyl position. Consequently, introduction of a halogen or a trifluoromethyl group at 3or 4position of the benzene ring enhanced PET inhibitory activity. All these compounds (2-(3or 4-substituted benzylamino)-4-methyl-6-trifluoromethyl-1,3,5-triazine derivatives) exhibited higher PET inhibitory activity than that of simazine. N-Alkyl derivatives of these triazines completely lost both PET inhibitory and herbicidal activities. However, the effect of N-acylation of 2-benzylamino-4-methyl-6trifluoromethyl-1,3,5-triazines on phytotoxic activities has not been reported. In this study, some 2-(N-acylbenzylamino)4-methyl-6-substituted-1,3,5-triazine derivatives were synthesized and evaluated to investigate the contribution of Nacylation of benzylamino group against PET inhibitory and herbicidal activities.