Rupa Mazumder

Antimicrobial potentiality of Phyllanthus amarus against drug resistant pathogens

The antimicrobial potentiality of the methanolic extract of Phyllanthus amarus (Family: Euphorbiaceae) was studied against some drug resistant pathogenic bacterial strains by disc diffusion and agar dilution method. The extract showed significant concentration-dependent antibacterial activity particularly against gram-negative microbes. The study illustrated the claim of the usefulness of the plant in dysenteric and diarrheal infections and also suggested its use in fever. The antibacterial action was mainly due to the isolated phyllanthin.

In vivo antitussive potentiality of Lagerstroemia parviflora flower extract using a cough model induced by sulfur dioxide in mice.

The methanol extract of the flowers of Lagerstroemia parviflora Roxb (Family: Lythraceae) was investigated for its effect on a cough model induced by sulphur dioxide gas in mice. It exhibited significant antitussive activity when compared with the control in a dose-dependent manner. The extract (100, 200, 300 mg kg−1) showed maximum inhibition of cough reflex at 90 min after drug administration and the antitussive activity was comparable to that of codeine phosphate, a standard antitussive agent.

Evaluation of Antipyretic Potential of Lagerstroemia parviflora. Extract in Rats

Abstract The methanol extract of Lagerstroemia parviflora. Roxb leaves was tested for antipyretic effects on rats. The extract (200 and 300 mg/kg, p.o.) showed very significant reduction of yeast-induced pyrexia in rats with respect to the control group. The antipyretic activity of the extract was comparable to the standard prototype, paracetamol.