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Dive into the research topics where Ryan Mills is active.

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Featured researches published by Ryan Mills.


Pediatrics | 2011

Child Abuse and Neglect and Cognitive Function at 14 Years of Age: Findings From a Birth Cohort

Ryan Mills; Rosa Alati; Michael O'Callaghan; Jake M. Najman; Gail M. Williams; William Bor; Lane Strathearn

OBJECTIVE: To examine the association between child maltreatment (abuse and neglect) and long-term cognitive outcomes within a prospective birth cohort. METHODS: A birth cohort of 7223 children was recruited. Independent reports of suspected child maltreatment were confidentially linked to the longitudinal study database. The principal predictor variable was notification to the state child-protection authority for suspected maltreatment (abuse, neglect, or both). The outcome variables were scores on the Wide Range Achievement Test (WRAT) reading test and Ravens Standard Progressive Matrices (RSPM), completed at 14 years of age. Multivariate regression analysis was used to adjust for potential confounders. RESULTS: A total of 3796 subjects completed either the WRAT or RSPM. There was a higher loss to follow-up among children who had been reported to the state as suspected victims of maltreatment. After controlling for a range of possible confounders and modifiers, notification to the state for child maltreatment (abuse, neglect, or both) was associated with a lower score on both the WRAT (mean difference: −4.4 when the SD is 15 [95% confidence interval: −6.3 to −2.5]) and RSPM (mean difference: −4.8 when the SD is 15 [95% confidence interval: −6.7 to −2.9]). Both reported abuse and neglect were independently associated with lower reading ability and perceptual reasoning. CONCLUSIONS: Both child abuse and child neglect are independently associated with impaired cognition and academic functioning in adolescence. These findings suggest that both abuse and neglect have independent and important adverse effects on a childs cognitive development.


Child Abuse & Neglect | 2013

Child maltreatment and adolescent mental health problems in a large birth cohort

Ryan Mills; James Scott; Rosa Alati; Michael O'Callaghan; Jake M. Najman; Lane Strathearn

OBJECTIVE To examine whether notified child maltreatment is associated with adverse psychological outcomes in adolescence, and whether differing patterns of psychological outcome are seen depending on the type of maltreatment. METHODS The participants were 7,223 mother and child pairs enrolled in a population-based birth cohort study in Brisbane, Australia. Exposure to suspected child maltreatment was measured by linkage with state child protection agency data. The primary outcomes were the internalizing and externalizing scales of the Youth Self Report (YSR) at approximately 14 years of age. RESULTS The YSR was completed by 5,172 subjects (71.6%), with increased attrition of cases of notified maltreatment. After adjustment for potential confounders, notified maltreatment was significantly associated with both internalizing behavior and externalizing behavior at 14. When evaluated as non-exclusive categories of maltreatment, physical abuse, neglect, and emotional abuse were each significantly associated with both internalizing and externalizing behavior after adjustment. When evaluated using an expanded hierarchical scheme that included combinations of multi-type maltreatment, the following groups had significantly higher internalizing behavior after adjustment: emotional abuse (with or without neglect), and multi-type maltreatment including physical (but not sexual) abuse with neglect and/or emotional abuse. The following groups were associated with externalizing behavior after adjustment: emotional abuse (with or without neglect), and multi-type maltreatment including physical abuse (with neglect and/or emotional abuse), or sexual abuse (with neglect and/or emotional abuse, and/or physical abuse). CONCLUSION This study suggests that child neglect and emotional abuse have serious adverse effects on adolescent mental health and warrant the attention given to other forms of child maltreatment. Additionally, it confirms that young people who are notified for more than one type of maltreatment are at particular risk of adolescent mental health problems.


Child Abuse & Neglect | 2015

Burden attributable to child maltreatment in Australia

Sophie E. Moore; James Scott; Alize J. Ferrari; Ryan Mills; Michael P. Dunne; Holly E. Erskine; Karen Devries; Louisa Degenhardt; Theo Vos; Harvey Whiteford; Molly McCarthy; Rosana Norman

Child maltreatment is a complex phenomenon, with four main types (childhood sexual abuse, physical abuse, emotional abuse, and neglect) highly interrelated. All types of maltreatment have been linked to adverse health consequences and exposure to multiple forms of maltreatment increases risk. In Australia to date, only burden attributable to childhood sexual abuse has been estimated. This study synthesized the national evidence and quantified the burden attributable to the four main types of child maltreatment. Meta-analyses, based on quality-effects models, generated pooled prevalence estimates for each maltreatment type. Exposure to child maltreatment was examined as a risk factor for depressive disorders, anxiety disorders and intentional self-harm using counterfactual estimation and comparative risk assessment methods. Adjustments were made for co-occurrence of multiple forms of child maltreatment. Overall, an estimated 23.5% of self-harm, 20.9% of anxiety disorders and 15.7% of depressive disorders burden in males; and 33.0% of self-harm, 30.6% of anxiety disorders and 22.8% of depressive disorders burden in females was attributable to child maltreatment. Child maltreatment was estimated to cause 1.4% (95% uncertainty interval 0.4-2.3%) of all disability-adjusted life years (DALYs) in males, and 2.4% (0.7-4.1%) of all DALYs in females in Australia in 2010. Child maltreatment contributes to a substantial proportion of burden from depressive and anxiety disorders and intentional self-harm in Australia. This study demonstrates the importance of including all forms of child maltreatment as risk factors in future burden of disease studies.


Addiction | 2014

Alcohol and tobacco use among maltreated and non-maltreated adolescents in a birth cohort

Ryan Mills; Rosa Alati; Lane Strathearn; Jake M. Najman

AIMS This study examines whether child maltreatment experience predicts adolescent tobacco and alcohol use. METHODS The subjects were participants in the Mater-University Study of Pregnancy (MUSP), a birth cohort of 7223, of whom 5158 (71.4%) were available for analysis at the 14-year follow-up. Child protection history was obtained from the states child protection agency and confidentially linked. Exposure to reported child maltreatment was the primary predictor variable. The outcome variables were self-reported smoking and alcohol use. Associations were adjusted for potential confounders. RESULTS Reported child maltreatment was associated with early adolescent smoking [odds ratio (OR) 1.76, 95% confidence interval (CI) = 1.32-2.34] after adjustment for socio-demographic variables and coexisting alcohol use. Both neglect/emotional abuse (OR 2.03, 95% CI = 1.20-3.42) and neglect/emotional abuse that included physical abuse (OR 1.85, 95% CI = 1.19-2.88) were associated with smoking after full adjustment, including for coexisting alcohol use. After full adjustment, including coexisting smoking, only child neglect/emotional abuse predicted early adolescent alcohol use (OR 1.78, 95% CI = 1.06-2.97), but not the other types of maltreatment. CONCLUSIONS Reported child maltreatment predicts early adolescent smoking after adjusting for alcohol use, but does not predict alcohol use after adjustment for smoking. Both smoking and alcohol use are predicted by reported child neglect. Early adolescent smoking is also predicted by multi-type maltreatment that includes physical abuse.


Journal of Psychiatric Research | 2016

Self-reported and agency-notified child sexual abuse in a population-based birth cohort

Ryan Mills; Steve Kisely; Rosa Alati; Lane Strathearn; Jake M. Najman

Child sexual abuse (CSA) has been associated with many adverse psychiatric outcomes. However, most studies have relied on retrospective self-report of exposure to CSA. We set out to investigate the incidence of CSA in the same birth cohort using both retrospective self-report and prospective government agency notification, and examine the psychological outcomes in young adulthood. The primary outcomes were measures of DSM-IV diagnoses (CIDI-Auto) at age 21. The 21-year retrospective CSA questions were completed by 3739 participants. CSA was self-reported by 19.3% of males and 30.6% of females. After adjustment for potential confounders, both self-reported and agency-notified CSA were associated with increased odds of lifetime major depressive disorder (MDD), anxiety disorders, and posttraumatic stress disorder (PTSD). For the first time in a birth cohort, this study has shown the disparity between the incidence of CSA when measured by self-report and government agency notification. Despite this discrepancy, adverse psychiatric outcomes are seen when CSA is defined using either method.


Child Abuse & Neglect | 2013

Does child abuse and neglect explain the overrepresentation of Aboriginal and Torres Strait Islander young people in youth detention? Findings from a birth cohort study

Ivan Doolan; Jake M. Najman; Ryan Mills; Adrian Cherney; Lane Strathearn

OBJECTIVE Determine whether a history of family social disadvantage and/or child abuse and neglect explain the overrepresentation of Indigenous Australian young people in youth detention. METHODS Maternal survey data from the Mater University Study of Pregnancy was linked with child abuse and neglect and youth justice data from the Queensland Department of Families, Youth and Community Care. RESULTS Indigenous Australian children were 1.81 times more likely to be notified to child protection authorities for maltreatment and 1.77 times more likely to have that maltreatment substantiated. Indigenous Australian young people were 3.07 times more likely to have a youth justice history. When adjusted for social disadvantage, the odds of the Indigenous Australian youth having had involvement with the youth justice authorities remained 2.51 times that of their non-Indigenous peers. When adjusted for substantiated maltreatment, the odds of the Indigenous Australian youth having had involvement with the youth justice authorities remained 2.83 times that of their non-Indigenous peers. When adjusted for both social disadvantage and substantiated maltreatment, the odds of the Indigenous Australian youth having had involvement with the youth justice authorities remained 2.48 times that of their non-Indigenous peers. CONCLUSIONS The overrepresentation of Australian Aboriginal and Torres Strait Islander young people in the youth justice system, including Youth Detention, is only partly explained by their greater social disadvantage and by their greater experience of substantiated maltreatment, either separately or combined.


Australian and New Zealand Journal of Psychiatry | 2018

Cognitive and educational outcomes of maltreated and non-maltreated youth: A birth cohort study:

Ryan Mills; Steve Kisely; Rosa Alati; Lane Strathearn; Jake M. Najman

Objectives: Previous research suggests that child maltreatment is associated with adverse outcomes, but the potential impact on cognitive and educational outcomes into adulthood has rarely been studied using a birth cohort design. The aim of this study is to investigate whether child maltreatment is associated with adverse outcomes in cognitive function, high school completion and employment by the age of 21. Methods: Longitudinal birth cohort study commencing in the prenatal period, with mothers and infants followed up to age 21. Of the original birth cohort of 7223, 3778 (52.3%) young people participated at age 21. Child maltreatment was identified by linkage with prospectively collected data from the relevant government agency. Associations between child maltreatment (abuse and neglect) and the outcomes were adjusted for relevant sociodemographic and perinatal variables. Results: After full adjustment, young people who had been notified as cases of child maltreatment had reduced performance on the Peabody Picture Vocabulary Test by over a quarter of a standard deviation (coefficient = −2.85, p = 0.004). Maltreated young people also had three times the odds of failing to complete high school (odds ratio = 3.12, p < 0.001) and more than twice the odds of not being engaged in either study or employment at age 21 (odds ratio = 2.38, p < 0.001). Both abuse and neglect were similarly associated with adverse outcomes. Conclusion: Child maltreatment, including both abuse and neglect, is associated with adverse cognitive, educational and employment outcomes in young adulthood. This adds further impetus to efforts to prevent child maltreatment and assist young people who have experienced it.


British Journal of Psychiatry | 2018

Child maltreatment and mental health problems in adulthood: birth cohort study

Steve Kisely; Amanuel Alemu Abajobir; Ryan Mills; Lane Strathearn; Alexandra Clavarino; Jake M. Najman

BACKGROUND Retrospective studies have shown a high association between child abuse and subsequent psychiatric morbidity. Prospective studies are rarer.AimsTo examine, using a prospective record-linkage analysis, whether substantiated child maltreatment is associated with adverse psychological outcomes in early adulthood. METHOD The participants were 3778 mother and child pairs enrolled in a population-based birth cohort study in Brisbane, Australia. Exposure to suspected child maltreatment was measured by linkage with state child protection agency data. The primary outcomes were the internalising and externalising scales of the Youth Self-Report and the Centre for Epidemiological Studies-Depression scales (CES-D) at approximately 21 years of age. A subset completed the Composite International Diagnostic Interview-Auto version (CIDI-Auto). RESULTS In total, 171 (4.5%) participants had a history of substantiated child maltreatment, most commonly emotional abuse (n = 91), followed by physical abuse (n = 78), neglect (n = 73) and sexual abuse (n = 54). After adjustment for potential confounders, depressive symptoms on the CES-D, as well as internalising and externalising behaviours were strongly associated with substantiated abuse in all forms, except sexual abuse. The results for the subset of the sample who completed the CIDI-Auto were less clear. Anxiety, especially post-traumatic stress disorder, showed the strongest association whereas the findings for depressive disorder were equivocal. However, across all diagnostic categories, emotional abuse and neglect, as well as multiple forms of abuse, showed a consistent association. CONCLUSIONS Child maltreatment, particularly neglect and emotional abuse, has serious adverse effects on early adult mental health. These two warrant the attention given to other forms of child maltreatment. Children experiencing more than one type of maltreatment are at particular risk.Declaration of interestNone.


Cochrane Database of Systematic Reviews | 2012

Enteral iron supplementation in preterm and low birth weight infants

Ryan Mills; Mark W Davies


Australian Journal of Psychology | 2011

Antisocial behaviour across the life course: An examination of the effects of early onset desistence and early onset persistent antisocial behaviour in adulthood

Tara Renae McGee; Mohammad R. Hayatbakhsh; William Bor; Michael Cerruto; Angela J. Dean; Rosa Alati; Ryan Mills; Gail M. Williams; Michael O'Callaghan; Jake M. Najman

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Jake M. Najman

University of Queensland

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Lane Strathearn

Boston Children's Hospital

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Rosa Alati

University of Queensland

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Steve Kisely

University of Queensland

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William Bor

University of Queensland

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James Scott

University of Queensland

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Adrian Cherney

University of Queensland

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