Ryo Nishikawa
University of Tokyo
Network
Latest external collaboration on country level. Dive into details by clicking on the dots.
Publication
Featured researches published by Ryo Nishikawa.
Journal of Clinical Oncology | 2018
Takamasa Kayama; Shinya Sato; Kaori Sakurada; Junki Mizusawa; Ryo Nishikawa; Yoshitaka Narita; Minako Sumi; Yasuji Miyakita; Toshihiro Kumabe; Yukihiko Sonoda; Yoshiki Arakawa; Susumu Miyamoto; Takaaki Beppu; Kazuhiko Sugiyama; Hirohiko Nakamura; Motoo Nagane; Yoko Nakasu; Naoya Hashimoto; Mizuhiko Terasaki; Akira Matsumura; Eiichi Ishikawa; Toshihiko Wakabayashi; Yasuo Iwadate; Shiro Ohue; Hiroyuki Kobayashi; Manabu Kinoshita; Kenichiro Asano; Akitake Mukasa; Katsuyuki Tanaka; Akio Asai
Purpose Whereas whole-brain radiotherapy (WBRT) has been the standard treatment of brain metastases (BMs), stereotactic radiosurgery (SRS) is increasingly preferred to avoid cognitive dysfunction; however, it has not been clearly determined whether treatment with SRS is as effective as that with WBRT or WBRT plus SRS. We thus assessed the noninferiority of salvage SRS to WBRT in patients with BMs. Patients and Methods Patients age 20 to 79 years old with performance status scores of 0 to 2-and 3 if caused only by neurologic deficits-and with four or fewer surgically resected BMs with only one lesion > 3 cm in diameter were eligible. Patients were randomly assigned to WBRT or salvage SRS arms within 21 days of surgery. The primary end point was overall survival. A one-sided α of .05 was used. Results Between January 2006 and May 2014, 137 and 134 patients were enrolled in the WBRT and salvage SRS arms, respectively. Median overall survival was 15.6 months in both arms (hazard ratio, 1.05; 90% CI, 0.83 to 1.33; one-sided P for noninferiority = .027). Median intracranial progression-free survival of patients in the WBRT arm (10.4 months) was longer than that of patients in the salvage SRS arm (4.0 months). The proportions of patients whose Mini-Mental Status Examination and performance status scores that did not worsen at 12 months were similar in both arms; however, 16.4% of patients in the WBRT arm experienced grade 2 to 4 cognitive dysfunction after 91 days postenrollment, whereas only 7.7% of those in the SRS arm did ( P = .048). Conclusion Salvage SRS is noninferior to WBRT and can be established as a standard therapy for patients with four or fewer BMs.
Genes, Chromosomes and Cancer | 1994
Takahiro Mori; Hiroki Nagase; Akira Horii; Yasuo Miyoshi; Shuichi Nakatsuru; Takahisa Aoki; Hirofumi Arakawa; Yusuke Nakamura; Takashi Shimano; Akio Yanagisawa; Yukitaka Ushio; Sadamu Takano; Michio Ogawa; Masato Nakamura; Masabumi Shibuya; Ryo Nishikawa; Masao Matsutani; Yasuhide Hayashi; Hitoshi Takahashi; Fusahiro Ikuta; Tetsuro Nishihira; Shozo Mori
Japanese Journal of Neurosurgery | 2000
Satoru Sugiyama; Seiichi Yamada; Ryo Nishikawa; Mitsuyoshi Hasebe; Akihiro Miyoshi; Hidehiko Yoshizawa; Hiroaki Ogura; Kuniyoshi Kumaido; Satoru Kubota; Masao Matsutani
Japanese Journal of Neurosurgery | 2015
Yonehiro Kanemura; Koichi Ichimura; Tomoko Shofuda; Mami Yamasaki; Soichiro Shibui; Hajime Arai; Ryo Nishikawa
Archive | 2014
Keita Terashima; Alexander Yu; Wing-Yuk Chow; Wei-chun J. Hsu; Peikai Chen; Stephen T. C. Wong; Yeung Sam Hung; Tomonari Suzuki; Ryo Nishikawa; Masao Matsutani; Hideo Nakamura; Ho-Keung Ng; Jeffrey C. Allen; Kenneth Aldape; J. Su; Adekunle M. Adesina; Hon-Chiu Eastwood Leung; Tsz-Kwong Man; Ching C. Lau
Archive | 2013
Prakash Ambady; Matthias Holdhoff; Clare Ferrigno; Stuart A. Grossman; Tomokazu Aoki; Ryo Nishikawa; Kazuhiko Sugiyama; Naosuke Nonoguchi; Noriyuki Kawabata; Kazuhiko Mishima; Jun-ichi Adachi; Kurisu K; Fumiyuki Yamasaki; Teiji Tominaga; Toshihiro Kumabe; Keisuke Ueki; Fumi Higuchi; Tetsuya Yamamoto; Eiichi Ishikawa; Hideo Takeshima; Shinji Yamashita; Hirofumi Hirano; Shinobu Yamada; Masao Matsutani
Archive | 2013
Keita Terashima; Alexander Yu; Wing-Yuk Chow; Wei-chun J. Hsu; Peikai Chen; Stephen T. C. Wong; Yeung Sam Hung; Tomonari Suzuki; Ryo Nishikawa; Masao Matsutani; Hideo Nakamura; Ho-Keung Ng; Jeffrey C. Allen; Kenneth Aldape; J. Su; Adekunle M. Adesina; Hon-Chiu Eastwood Leung; Tsz-Kwong Man; Ching C. Lau
Japanese Journal of Neurosurgery | 2005
Minori Morita; Jun-ichi Adachi; Ryo Nishikawa; Masao Matsutani
Japanese Journal of Neurosurgery | 2003
Tatsuya Sugiyama; Ryo Nishikawa; Masao Matsutani
Japanese Journal of Neurosurgery | 2002
Hiroyuki Nakajima; Jun-ichi Adachi; Ryo Nishikawa; Masao Matsutani