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Dive into the research topics where Ryozo Numazawa is active.

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Featured researches published by Ryozo Numazawa.


Bioscience, Biotechnology, and Biochemistry | 1993

Chemical Racemization of Methyl L-β-Acetylthioisobutyrate.

Akihiro Sakimae; Yoshimasa Kobayashi; Naoto Ohsuga; Ryozo Numazawa; Hisao Ohnishi

Methyl L-β-acetylthioisobutyrate was racemized with 1,8-diazabicyclo-[5.4.0]-undecene-7 as a catalyst. Methyl methacrylate and thioacetic acid were identified as the intermediates of the reaction. Thioacetic acid was relatively unstable and susceptible to decomposition during the racemization process. The addition of excess methyl mechacrylate to the reaction mixture prevented a decrease of the racemate. The racemized ester was confirmed to be usable as a substrate for the enzymatic production of D-β-acetylthioisobutyric acid.


Archive | 1981

Biochemical process for purifying contaminated water

Hisao Onishi; Ryozo Numazawa


Archive | 1978

Process and apparatus for waste water treatment

Hisao Onishi; Ryozo Numazawa; Hitoshi Takeda


Archive | 1990

Multi-layered porous hollow fiber membrane for use in cell culture

Takao Miyamori; Makoto Uchida; Kanehiko Enomoto; Akihiro Sakimae; Ryozo Numazawa


Bioscience, Biotechnology, and Biochemistry | 1995

Nucleotide Sequence of the Gene for a Thermostable Esterase from Pseudomonas putida MR-2068

Eiji Ozaki; Akihiro Sakimae; Ryozo Numazawa


Bioscience, Biotechnology, and Biochemistry | 1992

Screening of Microorganisms Producing D-β-Acetylthioisobutyric Acid from Methyl DL-β-Acetylthioisobutyrate

Akihiro Sakimae; Akihiko Hosoi; Etsuko Kobayashi; Naoto Ohsuga; Ryozo Numazawa; Ichiro Watanabe; Hisao Ohnishi


Archive | 1987

Method of producing hyaluronic acid

Takao Miyamori; Ryozo Numazawa; Akihiro Sakimae; Hisao Onishi


Archive | 1984

Process for preparing optically active carboxylic acids and antipode esters thereof

Akihiro Sakimae; Yuri Kagawa; Ryozo Numazawa; Hisao Onishi


Bioscience, Biotechnology, and Biochemistry | 1994

Cloning and Expression of Pseudomonas putida Esterase Gene in Escherichia coli and Its Use in Enzymatic Production of D-β-Acetylthioisobutyric Acid

Eiji Ozaki; Akihiro Sakimae; Ryozo Numazawa


Bioscience, Biotechnology, and Biochemistry | 1993

Process Conditions for Production of D-β-Acetylthioisobutyric Acid from Methyl DL-β-Acetylthioisobutyrate with the Cells of Pseudomonas putida MR-2068

Akihiro Sakimae; Eiji Ozaki; Hiroko Toyama; Naoto Ohsuga; Ryozo Numazawa; Itsumi Muraoka; Eiichi Hamada; Hisao Ohnishi

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