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Agricultural and biological chemistry | 1974

The Synthesis of α-Methylamino Acids

Mamoru Suzuki; Tsuyomi Miyahara; Ryuzo Yoshioka; Muneji Miyoshi; Kazuo Matsumoto

α-Methyltryptophan, α-methylhistidine, and α-methyldopa were prepared by the reaction of α-isocyanopropionates with gramine methiodide, the acetoxymethylimidazole derivative, and protected 3,4-dihydroxybenzyl bromides, respectively.


Journal of Organic Chemistry | 1983

Method for the racemization of optically active amino acids

Shigeki Yamada; Chikara Hongo; Ryuzo Yoshioka; Ichiro Chibata


Archive | 1982

Process for racemizing an optically active alpha-amino acid or a salt thereof

Ichiro Chibata; Shigeki Yamada; Chikara Hongo; Ryuzo Yoshioka


Archive | 1982

Process for racemizing optically active alpha -amino acids or a salt thereof

Ichiro Chibata; Shigeki Yamada; Chikara Hongo; Ryuzo Yoshioka


Bulletin of the Chemical Society of Japan | 1987

The Optical Resolution and Asymmetric Transformation of DL-p-Hydroxyphenylglycine with (+)-1-Phenylethanesulfonic Acid

Ryuzo Yoshioka; Masanori Tohyama; Osamu Ohtsuki; Shigeki Yamada; Ichiro Chibata


Bulletin of the Chemical Society of Japan | 1994

Optical Resolution, Characterization, and X-Ray Crystal Structures of Diastereomeric Salts of Chiral Amino Acids with (S)-(-)-1-Phenylethanesulfonic Acid.

Ryuzo Yoshioka; Osamu Ohtsuki; Tadamasa Date; Kimio Okamura; Masaru Senuma


Bulletin of the Chemical Society of Japan | 1985

Asymmetric Transformation of DL-p-Hydroxyphenylglycine by a Combination of Preferential Crystallization and Simultaneous Racemization of the o-Toluenesulfonate

Chikara Hongo; Masanori Tohyama; Ryuzo Yoshioka; Shigeki Yamada; Ichiro Chibata


Bulletin of the Chemical Society of Japan | 1983

Racemization of Optically Active Amino Acid Salts and an Approach to Asymmetric Transformation of DL-Amino Acids

Chikara Hongo; Ryuzo Yoshioka; Masanori Tohyama; Shigeki Yamada; Ichiro Chibata


Archive | 1982

P-hydroxyphenylglycine alpha-phenylethanesulfonate, process for production thereof and utilization thereof in resolution of p-hydroxyphenylglycine

Ichiro Chibata; Shigeki Yamada; Chikara Hongo; Ryuzo Yoshioka


Chemical & Pharmaceutical Bulletin | 1989

Efficient preparation of D-aspartic acid β-methyl ester as an aspoxicillin material by optical resolution, epimerization, and asymmetric transformation

Ryuzo Yoshioka; Osamu Ohtsuki; Masaru Senuma; Tetsuya Tosa

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Tetsuya Tosa

University of Pennsylvania

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