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Dive into the research topics where S. Carrera is active.

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Featured researches published by S. Carrera.


Journal of Clinical Oncology | 2008

Mutations of the p53 gene and microsatellite inestability (MSI) as prognostic factors in metastatic colorectal cancer (CRC)

B. Calvo; N. Fuente; Unai Aresti; M. Jangi; S. Carrera; Aitziber Buque; A. Sancho; P. Garrido; A. Ruiz de Lobera; Alberto Muñoz

22088 Background: Several genetic changes have been described associated with CRC, but the prognostic significance of most of them remains controversial. We analysed the distribution and the association with survival of some molecular markers in CCR tissues. Methods: From March-04 to June-05 73 patients were included with recent diagnosis of CRC: 53M/20F with a mean age of 70y (46–88). There were 25 rectal tumors (34%) and stage distribution was I:11, IIA:24, IIB:2, IIIA:3, IIIB:9, IIIC:8 and IV:16. During the anatomopathologic exam of the resected specimens, fresh samples were obtained (tumoral tissue and normal tissue), and they were stored in freezer vials at −86°C. In every sample all the following analysis were performed: LOH of the APC and DCC genes, MSI and Kras mutations using different biological techniques, and mutations of the p53 gene (exons 5 to 9) by sequence analysis. Results: LOH of DCC was found in 62% of the tumors, LOH of APC in 46% and MSI in 22% (MSI-LOW in 12 patients and MSI-HIGH in...


Clinical & Translational Oncology | 2014

Epidermal growth factor receptor tyrosine-kinase inhibitor treatment resistance in non-small cell lung cancer: biological basis and therapeutic strategies

S. Carrera; Aitziber Buque; Eider Azkona; Unai Aresti; B. Calvo; A. Sancho; Mikel Arruti; M. Nuño; Itziar Rubio; A. R. de Lobera; C. Lopez; Guillermo López Vivanco


Annals of Oncology | 2007

Reversible liver toxicity with adjuvant trastuzumab for localized breast cancer

Alberto Muñoz; S. Carrera; J. Ferreiro; A. Ruiz de Lobera; J. M. Mañé; Guillermo Lopez-Vivanco


Journal of Clinical Oncology | 2009

Gene expression profile of human colorectal cancer using oligonucleotide microarray

A. Munoz Llarena; A. Garcia; B. Suarez; M. Jangi; P. Garrido; J. M. Mañé; A. Sancho; A. Martinez; G. Lopez Vivanco; S. Carrera


Journal of Clinical Oncology | 2011

Preoperative chemoradiotherapy with capecitabine and oxaliplatin in patients with locally advanced rectal cancer.

Ines Marrodan; Eider Azkona; S. Carrera; Unai Aresti; B. Calvo; Aitziber Buque; A. Sancho; A. Ruiz de Lobera; A. Munoz Llarena; G. Lopez-Vivanco


Journal of Clinical Oncology | 2009

Effect of id1 and id2 proteins (inhibitors of dna binding) expression in human colorectal cell lines

B. Calvo; Alberto Muñoz; M. Jangi; Unai Aresti; A. Garcia; A. Alonso; Ines Marrodan; A. Moreno; G. Lopez-Vivanco; S. Carrera


Ejc Supplements | 2009

1341 Potential diagnostic markers in bronchial fluid of small cell lung cancer (SCLC)

G. Lopez Vivanco; S. Carrera; Laureano Simón; A. Gómez Bonilla; A. Martinez Bueno; D. Ballesteros Quintanilla; R. Zalacain Jorge; I. Marrodan Ciordia; A. Buque Martinez; E. Azkona Uribelarrea


Ejc Supplements | 2009

1338 Identification of potential diagnostic markers in bronchial fluid of patients with non small cell lung cancer (NSCLC)

S. Carrera; R. Zalacain Jorge; J. Algorta; A. Sancho Gutierrez; B. Calvo Martinez; I. Rubio Etxebarria; X. Mielgo Rubio; E. Iruarrizaga Ovejas; U. Aresti Goiriena; G. Lopez Vivanco


Ejc Supplements | 2009

9126 Bi-weekly paclitaxel-gemcitabine in patients with small-cell lung cancer resistant to previous platinum and etoposide-based chemotherapy

A. Martinez Bueno; X. Mielgo Rubio; E. Iruarrizaga Ovejas; S. Carrera; A. Ruiz de Lobera Martinez; R. Casas Cornejo; R. Fernandez Rodriguez; J. Ferreiro Quintana; D. Ballesteros Quintanilla


Journal of Clinical Oncology | 2008

Hepatic metastases (HM) from colorectal cancer (CRC): Resectability and survival after treatment with oxapliplatin or irinotecan + bevacizumab-based chemotherapy

Itziar Rubio; S. Carrera; A. Ruiz de Lobera; A. Sancho; P. Garrido; Ines Marrodan; I. Diaz de Corcuera; Alberto Muñoz; Eider Azkona; G. Lopez-Vivanco

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B. Calvo

University of Zaragoza

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Laureano Simón

Hospital Universitario La Paz

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