S.K. Kushawaha

SYNTHESIS, CHARACTERIZATION, AND BIOLOGICAL STUDIES ON SOME BIVALENT AND TRIVALENT TRANSITION METAL COMPLEXES OF N-BENZOYL-N′-THIOBENZHYDRAZIDE

ABSTRACT The complexes [M(L)(acac)], [M=Cr(III), Mn(III), Fe(III), Co(III)], [Mn(L)(H2O)2] and [Pd(HL)2] with N-benzoyl-N′-thiobenzhydrazide (H2L) have been prepared and characterized. Based on elemental analyses, magnetic susceptibility, electronic, NMR (1H and 13C), IR and ESR spectral data, a square-planar structure for [Pd(HL)2] and octahedral structures for the rest of the complexes have been proposed. The ligand and its soluble complexes have been screened for activity against a number of bacteria and P-815 (murine mastocytoma) tumor cells.

Complexes of N-nicotinoyl-N′-2-furanthiocarbohydrazide with oxovanadium(IV), manganese(II), iron(II & III), cobalt(II), nickel(II), copper(II) and zinc(II)

A new potential tetradentate ligand, N-nicotinoyl-N′-2-furanthiocarbohydrazide (H2Nfth), and its complexes with VOIV, MnII, FeII,III, CoII, NiII, CuII and ZnII have been prepared and characterized by elemental analyses, magnetic susceptibility measurements, u.v.–vis, i.r., n.m.r., ES+ and FAB mass spectral data. The room temperature e.s.r spectra of the VOIV and FeIII complexes yield 〈g〉 values, characteristic of octahedral complexes. The Mössbauer spectra of [Fe(HNfth)2] and [Fe2(Nfth)3] at room temperature and at 78 K suggest the presence of high-spin iron(II) and iron(III), respectively. The complexes are electrically insulating at room temperature, however, their conductivities increase as the temperature increases from 333–383 K, with a band gap of 0.46–0.77 eV, indicating their semiconducting behaviour. H2Nfth and its soluble complexes have been screened against several bacteria and fungi.

Synthesis, Characterization and Biological Activity of Some 3d Metal Complexes of N-isonicotinoyl-N1-2-furanthiocarbohydrazide

Abstract A new ligand, N-isonicotinoyl-N1-2-furanthiocarbohydrazide (H2INfth) has been prepared by the reaction of isonicotinic acid hydrazide and carboxymethyl-2-furandithioate. The complexes [VO(HINfth)2], [Mn(HINfth)2], [Fe(HINfth)2], [Fe(INfth)(acac)], M[(INfth)(H2O)2] [M = Co(II), Ni(II)], [M(INfth)] and [M(H2INfth)Cl2] [M = Cu(II), Zn(II)] have been prepared and characterized by elemental analyses, magnetic susceptibility, electronic, NMR, IR, mass and FAB mass spectral data. The room temperature ESR spectra of oxovanadium(IV) and iron(III) complexes yield values characteristic of square-pyramidal and octahedral complexes, respectively. The Mossbauer spectra of [Fe(HINfth)2] and [Fe(INfth)(acac)] at room temperature and 78 K suggest the presence of high-spin iron(II) and the intermediate spin state of iron(III) with an 4A2 ground state. The ligand and the complexes have been screened for activity against a number of bacteria and fungi.

N′-[Bis(benzyl­sulfan­yl)methyl­idene]-4-meth­oxy­benzohydrazide

In the title compound, C23H22N2O2S2, the dihedral angles between the 4-methoxy-substituted phenyl ring and the other two phenyl rings are 84.4 (4) and 77.7 (1)°, respectively, while the dihedral angle between the two phenyl rings is 57.5 (2)°. The amino group is not involved in an N—H hydrogen bond. The crystal packing is established by intermolecular C—H⋯O packing interactions involving a relatively rare weak three-center hydrogen bond between the keto O atom and H atoms of the two nearby phenyl rings, which link the molecules into chains running along the a axis. Additional weak intermolecular hydrogen-bond interactions between the 4-methoxy O atom and one of the phenyl rings and provide added stability to the crystal packing.

Complexes of N‐Picolinoyl‐N′‐2‐furanthiocarbohydrazide with Oxovanadium(IV), Manganese(III), Iron(III), Cobalt(II), Nickel(II), Copper(II), Zinc(II), and Cadmium(II)

Abstract The complexes [M(L)(H2O) x ] n [M = Co(II), Ni(II), Cu(II), Zn(II), Cd(II)] and [M2(L)3] n [M = Mn(III), Fe(III)] and [VO(HL)2] with N‐picolinoyl‐N′‐2‐furanthiocarbohydrazide (H2L) have been prepared and characterized by elemental analyses, magnetic susceptibility measurement, electronic, NMR (1H and 13C), IR and FAB mass spectral data. Physico‐chemical studies indicate that the complexes are polymeric in nature. The room temperature ESR spectra of [VO(HL)2] and [Cu(L)] n complexes yield ⟨g⟩ values, characteristic of square‐pyramidal and square‐planar complexes, respectively. The Mössbauer spectra of [Fe2(L)3] n at room temperature and at 78 K suggest the presence of high‐spin (S = 5/2) and low‐spin (S = 1/2) forms of Fe(III) in the same complex at both temperatures. The complexes of OV(IV), Fe(III), Ni(II), and Cd(II) show semiconducting behaviour in the solid state in the temperature range 307–397 K, with a band gap of 0.18–0.44 eV. The other complexes are insulators.

Synthesis, Characterization, and Electrical Conductivities of Some Transition Metal Complexes of N‐Nicotinoyl‐N′‐p‐hydroxythiobenzhydrazine

The complexes [M(L)]n, [M = VO(IV), Cu(II), Zn(II), Cd(II), Hg(II)] and [Fe(L)(acac)]n with N‐nicotinoyl‐N′‐p‐hydroxythiobenzhydrazine (H2L) have been prepared and characterized by elemental analyses, magnetic susceptibility measurements, electronic, NMR (1H and 13C), IR and FAB mass spectral data. The physico‐chemical studies indicate that the complexes are polymeric in nature. A square‐pyramidal structure for [VO(L)]n, an octahedral structure for [Fe(L)(acac)]n and a square‐planar structure for [Cu(L)]n have been proposed. The Mössbauer spectra of [Fe(L)(acac)]n at room temperature and at 78 K suggest the presence of high‐spin (S = 5/2) octahedral Fe(III). The complexes of VO(IV), Fe(III) and Hg(II) show semiconducting behavoiour in the solid state in the temperature range 307–397 K, with a band gap of 0.44–1.32 eV. The other complexes are insulators.