S.L. Znoyko

Biosensors based on magnetic nanolabels: Optimization with spectral interferometry and highly-sensitive electronic registration

A new rapid method based on immunochromatographic assay in combination with the electronic registration of nanolabels by their non-linear magnetization has been developed. The method is designed to provide highly accurate measurements of the concentration of protein molecules (e.g. markers, which indicate the onset or development of a disease) in various samples, including opaque solutions or strongly colored liquids. The optimization of the assay parameters is carried out using real-time monitoring of all the immunoassay steps with the spectral-correlation interferometry.