S. Samshuddin

1-[3,5-Bis(4-fluoro­phen­yl)-4,5-dihydro-1H-pyrazol-1-yl]ethanone

In the asymmetric unit of the title compound, C17H14F2N2O, there are three independent molecules (A, B and C) which differ slightly in the relative orientations of the two fluorophenyl rings. In molecules A and C one of the fluorophenyl rings is disordered over two positions, with occupancy ratios of 0.72 (2):0.28 (2) for molecule A and 0.67 (2):0.33 (2) for molecule C. The dihedral angle between the two fluorophenyl rings in the independent molecules lie in the range 70.3 (3)–84.0 (3)°. In the crystal structure, the molecules are linked via intermolecular C—H⋯O and C—H⋯F hydrogen bonds and π⋯π stacking interactions [centroid–centroid distance = 3.7508 (13) Å], forming a three-dimensional network.

Methyl 4,6-bis­(4-fluoro­phen­yl)-2-oxo­cyclo­hex-3-ene-1-carboxyl­ate

The 3-cyclohexene units adopt envelope conformations in each of the two independent molecules that comprise the asymmetric unit of the title compound, C20H16F2O3. The dihedral angles between the two fluorophenyl rings are 79.7 (2) and 73.7 (2)° in the two molecules. In one of the molecules, two C—H groups of the cyclohexene ring are disordered over two sets of sites in a 0.818 (13):0.182 (13) ratio, the major and minor components corresponding to the two enantiomeric forms of the molecule. Weak intermolecular C—H⋯O interactions help to stabilize the crystal structure.

3,5-Bis(4-fluorophenyl)-1-phenyl-4,5-dihydro-1H-pyrazole

In the title compound, C21H16F2N2, the dihedral angle between the fluorophenyl groups is 66.34 (8)°, and the dihedral angle between the envelope-configured pyrazole group (N/N/C/C/C) and the benzene ring is 11.50 (9)°. The dihedral angles between the benzene and the two fluoro-substituted phenyl groups are 77.7 (6) and 16.7 (5)°. Weak C—H⋯π interactions contribute to the stability of the crystal structure.

3,5-Bis(4-fluoro-phen-yl)-4,5-dihydro-1H-pyrazole-1-carbaldehyde.

In the title molecule, C16H12F2N2O, the pyrazole ring adopts a slight envelope conformation with the methylene C atom deviating by 0.114 (3) Å from the mean plane of the other four atoms [maximum deviation = 0.021 (3) Å]. The dihedral angles between the four essentially planar atoms of the pyrazole ring and the fluoro-substituted benzene rings are 2.6 (2) and 82.2 (2)°. The dihedral angle between the two benzene rings is 83.7 (2)°. The crystal packing is stabilized by weak intermolecular C—H⋯O hydrogen bonds.

3,5-Bis(4-bromo­phen­yl)-1-phenyl-4,5-dihydro-1H-pyrazole

In the title compound, C21H16Br2N2, the central pyrazole ring adopts an flattened envelope conformation, with the stereogenic C atom in the flap position. The deviations from planarity for this ring are relatively minor (r.m.s. deviation = 0.045 Å) and the dihedral angles formed with the N- and Cimine-bound benzene rings are 7.73 (13) and 11.00 (13)°, respectively. By contrast, the benzene ring bound at the chiral C atom is almost orthogonal to the rest of the molecule; the dihedral angle formed between this ring and the pyrazole ring is 79.53 (13)°. In the crystal, the packing is stabilized by C—H⋯N and C—H⋯Br interactions.

2,3-Dibromo-1,3-bis­(4-fluoro­phen­yl)propan-1-one

In the title compound, C15H10Br2F2O, the dihedral angle between the two 3-fluoro-substituted benzene rings is 5.7 (5)°. The two bromine substituents on the chalcone moiety are close to anti as the Br—C—C—Br torsion angle is 176.9 (7)°. Weak C—Br⋯π interactions may contribute to the crystal stability.

2,4-Bis(4-fluoro-phen-yl)-2,3-dihydro-1H-1,5-benzodiazepine.

In the title compound, C21H16F2N2, the seven-membered 1,4-diazepine ring of the benzodiazepine ring system adopts a distorted-boat conformation. The benzene ring of this system makes dihedral angles of 18.6 (2) and 78.8 (2)° with those of two fluorophenyl substituents. In the crystal, inversion dimers linked by two weak C—H⋯F hydrogen bonds generate R 2 2(20) ring motifs. There are also weak N—H⋯π and C—H⋯π interactions.

1-(4,4′′-Difluoro-5′-meth­oxy-1,1′:3′,1′′-terphenyl-4′-yl)ethanone

In the title compound, C21H16F2O2, the central benzene ring is inclined at dihedral angles of 30.91 (8) and 46.88 (7)° to the two terminal fluoro-substituted rings. The dihedral angle between the two terminal fluoro-subsituted rings is 68.34 (8)°. An intramolecular C—H⋯O hydrogen bond generates an S(6) ring motif. The crystal structure is stabilized by weak C—H⋯π interactions.

1,3-Bis(4-fluoro-phen-yl)-N,N'-(propane-1,3-diyl-idene)dihydroxyl-amine.

The title compound, C15H12F2N2O2, crystallizes with two molecules (A and B) in the asymmetric unit. Both aromatic rings of both molecules are disordered over two orientations [occupancy ratios of 0.768 (3):0.232 (3) and 0.770 (3):0.230 (3) for molecule A and 0.789 (3):0.211 (3) and 0.789 (3):0.211 (3) for molecule B]. The dihedral angles between the planes of the major and minor components of the disordered aromatic rings are 72.0 (4) and 71.2 (4)° for molecule A, and 70.2 (4) and 71.5 (2)° for molecule B. In the crystal, both molecules form inversion dimers with R 2 2(6) ring motifs via pairs of intermolecular O—H⋯N hydrogen bonds. The dimers are linked, forming zigzag C(7) chains along the c axis. Weak C—H⋯π interactions help to consolidate the packing.

5-(4,4′′-Difluoro-5′-hy­droxy-1,1′:3′,1′′-terphenyl-4′-yl)-3-(morpholin-4-ylmeth­yl)-1,3,4-oxadiazole-2(3H)-thione

In the title compound, C25H21F2N3O3S, the morpholine ring adopts a chair conformation. The 1,3,4-oxadiazole-2(3H)-thione group makes dihedral angles of 78.69 (8), 53.56 (7) and 55.30 (9)° with the benzene rings. In the crystal, O—H⋯O, C—H⋯S and C—H⋯F hydrogen bonds linked the molecules into layers lying parallel to the ab plane. Weak C—H⋯π interactions also occur.