S. Szönyi

Nouvelles methodes de preparation des F-alkyl oxiranes a partir des acetates de bromo-2 F-alkyl-2 ethyle et des bromo-2 F-alkyl-2 ethanol

Abstract F-alkyl oxiranes provide many interesting intermediates. Their synthesis from 2-bromo-2-F-alkylethyl acetates and from 2-bromo-2-F-alkylethanols was improved by two different methods which are very easy to apply. One requires the use of concentrated caustic soda and a phase transfer catalysts; the other one, potassium fluoride in triethylene glycol.

Reactions d'ouverture des F-alkyl oxirannes

Abstract Reactivity of F-alkyl oxirans was investigated towards nucleophilic and electrophilic reagents. They are quite inert in acid medium. On the other hand, in basic medium they lead to regiospecific opening reactions. Their reactions with organometallic compounds need extreme conditions : with Grignard reagents they sometimes lead to unexpected results.

Methodes simples de cis-hydroxylation des F-alkyl ethylenes

Abstract Synthesis of 2-F-alkyl ethane-1,2 diols from F-alkyl ethylenes and permanganates is reported. Among the three methods tested and described, one, carried out in a homogeneous non aqueous phase (CH 2 Cl 2 ) and with a stoechiometric amount of Phase Transfer Catalysis Agent (PCTA) gave the best yields (⋍80%).

Synthesis and physicochemical properties of new vesicle-forming fluorosurfactants derived from substituted dithioacetamides

Abstract New fluorine-containing double-chain surfactants have been prepared from substituted dithioacetamides; a distinctive feature of some of the surfactants prepared is that they contain a polymerizable group located on the ammonium head group. The aggregation behavior of four of the surfactants has been studied by freeze-fracture electron microscopy. The investigation has shown that under bath sonication all surfactants formed vesicles in water.

Liposomes and liposome-like vesicles in perfluorocarbon emulsions

Abstract Transmission electron microscopic examinations of perfluorocarbon emulsions have been made to investigate the influence of liposomes and liposome-like vesicles on the stability of these emulsions. Lecithin and the fluorinated quaternary ammonium salt F 13 C 6 CH(OH)CH 2 NHC 2 H 4 N(CH 3 ) 2 C 12 H 25 Br were used as emulsifiers. In contrast to what had been expected, no indications of perfluorocarbon inclusions in liposome-like vesicles were found.

New and Effective Route to N-(2-F-Alkyl Ethyl) α-Amino Acids

Abstract A new and effective procedure is described for the synthesis of N-F-alkylated α-amino acids which involves a Solid-Liquid Phase Transfer Catalysis (SL-PTC) method.

Synthesis of New F-Alkyl β-Amino Alcohols

Abstract F-alkyl oxiranes 1 and p-methylbenzene sulfonate ester intermediates 3 derived from 2-F-alkyl ethane -1,2-diols 2 are converted into F-alkyl β-amino alcohols 5 respectively by a two-step process.

Methode de preparation d'un nouveau precurseur d'agents tensioactifs perfluores: le F-hexyl thiiranne

Abstract The synthesis of a new thiirane (C 6 F 13 - ) is described. This compound is of interest as a potential precursor for new perfluorinated surfactants possessing the -SH group.

Nouveaux amphiphiles cationiques perfluoroalkylés dérivés des 1-monotosylate et 1-monobromoacetate de 2-F-alkyl 2-bromo ethanols. II

Abstract Tosylation, esterification and etherification reactions have been investigated for 2- F -alkyl-2-bromo-ethanols. Intermediates containing a tosyl group or a bromine atom could be converted into the corresponding F -alkylated cationic amphiphiles by means of secondary and tertiary amines.

New amphoteric surfactants containing the 2-perfluoroalkyl 2-hydroxy ethyl group and an amino acid residue

Amphoteric perfluoroalkylated surfactants containing a hydroxyl group were prepared by the addition of 2-perfluoroalkyl-1,2-epoxy ethane to a starting (L,D or L) amino acid (glycine, alanine, β-alanine, serine, 2-amino butyric acid, norvaline, norleucine, methionine, sarcosine, aspartic acid, glutamic acid).