S. Ubezio

Pityriasis versicolor in a newborn Pityriasis versicolor bei einem Neugeborenen

Summary. Pityriasis versicolor is a superficial mycosis that rarely afflicts children. We present a case in a 2‐month‐old male baby in good health, with hyper‐ and hypopigmented macules located in the cervical region and on the scalp, face and chest. Moreover, we report our record of cases in infancy and the predisposing factors.

Hepatosplenic infection caused by Candida parapsilosis in patients with acute leukaernia

Zusammenfassung. Candida parapsilosis ist als Erreger der hepatolienalen Candidose ungewöhnlich. In dieser Arbeit werden zwei Fälle von Candida parapsilosis‐bedingter hepatolienaler Candidose an zwei Patienten mit akuter Leukämie vorgestellt. Die mykologische Diagnose erfolgte an Kulturen aus Material von offenen LeberMilz‐Biopsien bei herabgesetzter Dosierung der systemischen antimykotischen Therapie. Der Bericht bestätigt die Wichtigkeit einer frühzeitigen Diagnose dieser Erkrankung als Entscheidungshilfe für eine angemessene antimykotische Chemotherapie.

Specific and non-specific parameters of the host defence system in patients with superficial fungal infections

Summary. Some measures of systemic host defences, i.e. white cell counts, lymphocyte subsets, delayed‐type hypersensitivity and polymorphonuclear leucocyte functions, were evaluated in 42 patients suffering from cutaneous superficial mycoses and in 35 healthy volunteers. Patients were divided according to the extent of their lesions into two groups: group A (30 patients) with skin involvement ≥30% and group B (12 patients) with skin involvement ≤1%. No significant abnormalities in systemic defence mechanisms were observed in group B patients, whereas multiple alterations of polymorphonuclear phagocyte activities, i.e. chemotaxis, phagocytosis, mitogeninduced superoxide anion production, were observed in patients with extensive lesions. The values of these phagocytic functions remained significantly reduced (P<0.01) in these patients after recovery and during a 6‐month follow‐up period.