Sachie Otsuki
Merck & Co.
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Publication
Featured researches published by Sachie Otsuki.
Bioorganic & Medicinal Chemistry Letters | 2009
Yoshiyuki Sato; Yu Onozaki; Tetsuya Sugimoto; Hideki Kurihara; Kaori Kamijo; Chie Kadowaki; Toshiaki Tsujino; Akiko Watanabe; Sachie Otsuki; Morihiro Mitsuya; Masato Iida; Kyosuke Haze; Takumitsu Machida; Yoko Nakatsuru; Hideya Komatani; Hidehito Kotani; Yoshikazu Iwasawa
A novel class of imidazopyridine derivatives was designed as PLK1 inhibitors. Extensive SAR studies supported by molecular modeling afforded a highly potent and selective compound 36. Compound 36 demonstrated good antitumor efficacy in xenograft nude rat model.
Bioorganic & Medicinal Chemistry Letters | 2006
Tadashi Shimamura; Jun Shibata; Hideki Kurihara; Takashi Mita; Sachie Otsuki; Takeshi Sagara; Hiroshi Hirai; Yoshikazu Iwasawa
Archive | 2013
Takeshi Sagara; Satoru Ito; Sachie Otsuki; Hiroshi Sootome
Archive | 2013
Takeshi Sagara; Satoru Ito; Sachie Otsuki; Katsumasa Nonoshita
Archive | 2013
Takeshi Sagara; Satoru Ito; Sachie Otsuki; Katsumasa Nonoshita
Archive | 2013
Takeshi Sagara; 武 相良; Satoru Ito; 伊藤 智; Sachie Otsuki; 幸恵 大槻; Kazuhiro Fukasawa; 和臣 深澤; Masaya Hashimoto; 雅也 橋本
Archive | 2007
Takeshi Sagara; Sachie Otsuki; Satoshi Sunami; Toshihiro Sakamoto; Kenji Niiyama; Fuyuki Yamamoto; Takashi Yoshizumi; Hidetomo Furuyama; Yasuhiro Goto; Makoto Bamba; Keiji Takahashi; Hiroshi Hirai; Toshihide Nishibata
Archive | 2013
Takeshi Sagara; 武 相良; Satoru Ito; 伊藤 智; Sachie Otsuki; 幸恵 大槻; Hiroshi Sootome; 裕 五月女
Archive | 2013
Takeshi Sagara; 武 相良; Satoru Ito; 伊藤 智; Sachie Otsuki; 幸恵 大槻; Hiroshi Sootome; 裕 五月女
Archive | 2009
Toshiiro Sakamoto; Satoshi Sunami; Fuyuki Yamamoto; Kenji Niyama; Makoto Bamba; Keiji Takashi; Hidetomo Furuyama; Takeshi Sagara; Sachie Otsuki; Toshihide Nishibata; Takashi Yoshizum; Hiroshi Hirai
