Saeed Attar

Ferrocenyl chalcones versus organic chalcones: a comparative study of their nematocidal activity.

A series of 30 organic chlacones and 33 ferrocenyl (Fc) chalcones were synthesized and characterized by melting point, elemental analysis, spectroscopy ((1)H NMR and FTIR) and, in two cases, by X-ray crystallography. The biological activity of each compound (10(-4)M in DMSO) against the model nematode Caenorhabditis elegans was examined in terms of % mortality (percent nematodes that died) and % fecundity (percent nematodes that reproduced) and compared to that obtained for the control medium (1% DMSO) over a 14-day period. Detailed conformational analyses for two Fc-chalcones (studied also by X-ray crystallography) were performed via molecular modeling studies. In general, the organic chalcones were found to be less polar than their Fc analogs. Some structure-activity relationships (SARs) were determined: (a) The nematocidal activities of the organic chalcones in this series were found to be much greater than those of their ferrocenyl analogs. (b) The position of the carbonyl group played a central role in the biological activity of both classes of chalcones studied. (c) For both classes of chalcones, lipophilicity of a compound seemed to play a significant role in its nematocidal activity. (d) The planarity of a ferrocenyl-chlacone seems to play a role in its activity.

Cation and hydrogen bonding effects on the self-association and luminescence of the dicyanoaurate ion, [Au(CN)2]−

The colorless salts [C5H10NH2][AuI(CN)2], [C4H8NH2][AuI(CN)2], [Ph2NNH3][AuI(CN)2]·H2O and [(n-C3H7)4N][AuI(CN)2]·H2O have been prepared by evaporation of aqueous solutions of potassium dicyanoaurate and the chloride salt of the appropriate cation. Hydrogen bonding between the cations and the cyano groups of the anions facilitates the formation of structures with strong aurophilic interactions between the anions. Thus, the [Au(CN)2]− ions self-associate in the three salts [C5H10NH2][AuI(CN)2] (Au⋯Au 3.0969(3) A), [C4H8NH2][AuI(CN)2] (Au1⋯Au2 3.0795(4) A), [Ph2NNH3][AuI(CN)2]·H2O (Au⋯Au 3.0866(4) A), while in [(n-C3H7)4N][AuI(CN)2]·H2O, which lacks N–H units, the gold ions are widely dispersed. The crystals of [C5H10NH2][AuI(CN)2], [C4H8NH2][AuI(CN)2] and [Ph2NNH3][AuI(CN)2]·H2O each show strong blue luminescence at room temperature, while [(n-C3H7)4N][AuI(CN)2]·H2O is non-luminescent.

Axial ligation modulates the electron distribution in helical cobalt complexes derived from octaethylbilindione

Addition of pyridine to the four-coordinate cobalt(II) complex, [Co II (oebOx)]I 3 , which shows an EPR spectrum with well resolved Co hyperfine coupling, converts the complex into one with Co III /ligand radical structure and an EPR spectrum with g z = 1.98, and g xy = 2.02 and no cobalt hyperfine coupling.

Crystallographic characterization of the helical diketone, C36H14O2, a new product from the flash vacuum pyrolysis of decacyclene in the presence of oxygen

The helical diketone, C36H14O2, is formed during the flash vacuum pyrolysis of decacyclene in the presence of oxygen and has been characterized by X-ray crystallography.