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Saibaba Racha

Bristol-Myers Squibb

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Publication

Featured researches published by Saibaba Racha.

Tetrahedron Letters | 1995

5′-Benzoyl-2′α-bromo-3′-O-methanesulfonylthymidine: A superior nucleoside for the synthesis of the anti-AIDS drug D4T (Stavudine)

Bang-Chi Chen; Sandra L. Quinlan; Derron R. Stark; J. Gregory Reid; Vicki H. Audia; Jacqueline G. George; Emerich Eisenreich; Steve P. Brundidge; Saibaba Racha; Richard H Spector

Summary The anti-AIDS drug d4T is prepared in 75% overall yield starting from the readily available ribonucleoside 5-methyluridine ( 1 ). The key step in this new synthesis is the zinc-induced reductive elimination of the bromomesylate 4 , which affords d4T without nucleoside bond cleavage. A facile procedure for the deprotection/isolation of this highly water soluble product is also described.

Archive | 2005

Process for preparing a dipeptidyl peptidase IV inhibitor and intermediates employed therein

Padam N. Sharma; Edward J. Gublo; Gabriel M. Galvin; Susan D. Boettger; Saibaba Racha

Archive | 2005

Ammonolysis process for the preparation of intermediates for DPP IV inhibitors

Padam N. Sharma; Gabriel M. Galvin; Susan D. Boettger; Saibaba Racha; Jingyang Zhu; Jack Melton; Boguslaw Mudryk

Tetrahedron | 2003

Use of N-trifluoroacetyl-protected amino acid chlorides in peptide coupling reactions with virtually complete preservation of stereochemistry

Paul A. Jass; Victor W. Rosso; Saibaba Racha; Nachimuthu Soundararajan; John J. Venit; Andrew Rusowicz; Shankar Swaminathan; Julia Livshitz; Edward J. Delaney

Canadian Journal of Chemistry | 1994

Practical synthesis of 4-aryl- and 4-heteroarylazetidin-2-ones: applications in the synthesis of the Taxol® side chain

Allan W. Rey; Robert Droghini; James L. Douglas; Purushotham Vemishetti; Susan D. Boettger; Saibaba Racha; John L. Dillon

Archive | 1999

PREPARATION OF [4S-(4α,7α,10Aβ)]-4-AMINO-OCTAHYDRO-5-OXO-7H-PYRIDO[2,1-B][1,3]THIAZEPINE-7-CARBOXYLIC ACID, METHYL ESTER AND SALTS THEREOF VIA NOVEL DISULFIDES

Jerome L. Moniot; Sushil K. Srivastava; William J. Winter; John J. Venit; Shankar Swaminathan; Keith Ramig; Paul A. Jass; Mark D. Schwinden; John L. Dillon; Saibaba Racha; James H. Simpson; Chien-Kuang Chen; Shawn K. Pack

Archive | 1999

Preparation of (s)-2-amino-6,6-dimethoxyhexanoic acid methyl ester via novel dioxolanes

Jollie D. Godfrey; David R. Kronenthal; Mark D. Schwinden; Sushil K. Srivastava; Keith Ramig; John J. Venit; Paul A. Jass; Saibaba Racha; John L. Dillon; Nachimuthu Soundararajan; Gerald L. Powers; Atul S. Kotnis

Archive | 2005

Alkyl and aryl-thiotrifluoroacetates and process

Padam N. Sharma; Edward J. Gublo; Susan D. Boettger; Saibaba Racha; John J. Usher

Archive | 2005

Novel alkyl- and aryl-thiotrifluoroacetates and process

Padam N. Sharma; Edward J. Gublo; Susan D. Boettger; Saibaba Racha; John J. Usher

Archive | 2005

Procede d'ammonolyse destine a la preparation d'intermediaires pour des inhibiteurs iv dpp

Padam N. Sharma; Gabriel M. Galvin; Susan D. Boettger; Saibaba Racha; Jingyang Zhu; Jack Melton; Boguslaw Mudryk

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Collaboration

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Susan D. Boettger

Bristol-Myers Squibb

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Padam N. Sharma

Bristol-Myers Squibb

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Edward J. Gublo

Bristol-Myers Squibb

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Gabriel M. Galvin

Bristol-Myers Squibb

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John J. Usher

Bristol-Myers Squibb

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John J. Venit

Bristol-Myers Squibb

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John L. Dillon

Bristol-Myers Squibb

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Paul A. Jass

Bristol-Myers Squibb

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Keith Ramig

Bristol-Myers Squibb

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Mark D. Schwinden

Bristol-Myers Squibb

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