Saïd Boujraf

Assessment of adsorption kinetics for removal potential of Crystal Violet dye from aqueous solutions using Moroccan pyrophyllite

Abstract This study involves the adsorption of Crystal Violet (CV) dye adsorbed from solution on the pyrophyllite’s surface. The batch technique was used under a variety of conditions to produce quantitative adsorption, namely amount of adsorbent, dye concentration, contact time, pH solution and temperature. The maximum adsorption capacity of Crystal Violet on pyrophyllite was 9.58 mg/g for 10 mg/L of CV concentration, pH = 6.8 at a temperature 20 °C and 1 g/L of adsorbent. This study of adsorption kinetics was carried out within framework of three models: intraparticle diffusion, pseudo-first order and pseudo-second order. The experimental isotherm data were analyzed using Langmuir and Freundlich models. Different thermodynamic parameters have shown spontaneous reaction with endothermic nature (The estimated value for ΔG was −7.64 kJ/mol at 293 K). Various techniques for characterizing the adsorbent were applied including X-ray diffraction (XRD), X-ray fluorescence spectroscopy (XRF), scanning electron microscopy (SEM) and transmission electron microscopy (TEM) coupled by energy dispersive X-ray spectroscopy (EDX). In addition, the regenerated adsorbents technique was reused several times; this demonstrated an economical aspect of using pyrophyllite which underlines the re-use importance considering the material capacity to regenerate.

Exceptional Association Between Klinefelter Syndrome and Growth Hormone Deficiency

Klinefelter syndrome (KS) is characterized in adults by the combination of a tall stature, small testes, gynecomastia, and azoospermia. This case is described in a North African population of the Mediterranean region of North Africa. We report the case of a male 16 years old, of Arab ethnic origin, and diagnosed with this syndrome, who had a small height in relation to a growth hormone (GH) deficiency and a history of absence seizures (generalized myoclonic epilepsy). The patient′s size was <−2.8 standard deviation (SD) with weight <−3 SD. GH deficiency was isolated and confirmed by two dynamic tests (insulin - hypoglycemia tolerance test and clonidine) with normal hypothalamic magnetic resonance imaging (MRI). GH supplementation using recombinant GH was advocated, while gonadotropin treatment was deferred. Small size in children or adolescents should not eliminate the diagnosis of Klinefelter syndrome - on the contrary, the presence of any associated sign (brain maturation, delay in puberty, aggressiveness) should encourage one to request a karyotype for the diagnosis and appropriate care of any case of KS that can be associated with GH deficiency, or which is in a variant form (isochromosome Xq, 49,XXXXY).

Depression and type 2 diabetes in developed and developing countries

DOI: 10.4103/2230-8210.126591 of this population, 95%[2] have type 2 diabetes. In front of t his huge pandemic, problems faced by children with type 1 diabetes are often overlooked. To address the critical gap in the management of type 1 diabetes in India, the Changing Diabetes in Children (CDiC) program was launched by Novo Nordisk Education Foundation in September 2011. The objective of the program is giving children, who are below the poverty line, access to comprehensive diabetes care.

EGFR Amplification and IDH Mutations in Glioblastoma Patients of the Northeast of Morocco

Glioblastomas are the most frequent and aggressive primary brain tumors which are expressing various evolutions, aggressiveness, and prognosis. Thus, the 2007 World Health Organization classification based solely on the histological criteria is no longer sufficient. It should be complemented by molecular analysis for a true histomolecular classification. The new 2016 WHO classification of tumors of the central nervous system uses molecular parameters in addition to histology to reclassify these tumors and reduce the interobserver variability. The aim of this study is to determine the prevalence of IDH mutations and EGFR amplifications in the population of the northeast region of Morocco and then to compare the results with other studies. Methods. IDH1 codon 132 and IDH2 codon 172 were directly sequenced and the amplification of exon 20 of EGFR gene was investigated by qPCR in 65 glioblastoma tumors diagnosed at the University Hospital of Fez between 2010 and 2014. Results. The R132H IDH1 mutation was observed in 8 of 65 tumor samples (12.31%). No mutation of IDH2 was detected. EGFR amplification was identified in 17 cases (26.15%). Conclusion. A systematic search of both histological and molecular markers should be requisite for a good diagnosis and a better management of glioblastomas.