Saikat Datta

Primary Multi Drug Resistant Extra-pulmonary Tuberculosis Presenting as Cervical Lymphadenitis.

DOI: 10.4103/0974-777X.132064 4. Abe K, D’Angelo MT, Sunenshine R, Noble-Wang J, Cope J, Jensen B, et al. Outbreak of Burkholderia cepacia bloodstream infection at an outpatient hematology and oncology practice. Infect Control Hosp Epidemiol 2007;28:1311-3. 5. Heo ST, Kim SJ, Jeong YG, Bae IG, Jin JS, Lee JC. Hospital outbreak of Burkholderia stabilis bacteraemia related to contaminated chlorhexidine in haematological malignancy patients with indwelling catheters. J Hosp Infect 2008;70:241-5.

Nutrient adequacy and its correlation in a sub-Himalayan region of West Bengal, India

Introduction: Nutrient adequacy is the level of intake of an essential nutrient in relation to the nutrient requirement for adequate health, which is expressed as the percentage of recommended dietary allowance. To develop an effective nationwide preventive program to combat malnutrition, it is necessary not only to assess the nature and magnitude of the problem of nutrient inadequacy but to identify factors affecting it especially at the household level. Objective: To estimate the prevalence of nutrient adequacy in a sample of households in a rural area of Darjeeling district and to find out the factors associated with nutrient adequacy. Materials and Methods: A community-based cross-sectional study was carried out from January 2014 to December 2014 in 821 households of Darjeeling district, India. The major dependent variable used in this study was the mean nutrient adequacy ratio of a household and the independent variables were number of family members, number of under-five children in the family, literacy of head of the family, literacy of the wife of the head of the family, income of the family, and percentage expenditure on food. Results: The prevalence of nutrient adequate households was found to be 35.3% among the study households. It was observed that the percentage expenditure on food had the highest contribution toward nutrient adequacy, followed by number of under-five children in the family and literacy of the wife of the head of the family. Undernutrition was found to be prevalent in 56.6% of the households. Conclusion: Majority of the study population had a diet less than the required amount and expectedly, undernutrition was also present in huge proportions.

Study of metabolic complications after 1 year of antiretroviral therapy in HIV-infected patients in a tertiary care center in North Bengal

Aim: There are conflicting data regarding the incidence of metabolic abnormalities in human immunodeficiency virus (HIV)-naive patients on antiretroviral therapy (ART). Also, recommendations for the monitoring of fasting lipid and glucose by major world bodies is annually while this study demonstrates that significant changes occur in as early as 6 months. Design: The incidence and pattern of metabolic complications have been studied in a case series study design at a tertiary care center through 1 year of ART. Materials and Methods: One hundred and twenty patients were followed for 1 year after initiating ART. Data collection and categorization were done according to the statistical software application such as mean comparison and one-way analysis of variance (ANOVA) using the statistical software IBM-SPSS (version 19 Chicago Inc.) assuming the significance at 95% of confidence interval (CI). Results: At the baseline, total mean cholesterol was 162.25 mg/dL, triglyceride (TG) was 126.57 mg/dL, Low-density lipoprotein cholesterol (LDL-c) was 99.14 mg/dL and high-density lipoprotein cholesterol (HDL-c) was 36.96 mg/dL. At 6 months total cholesterol (TC), LDL-c, TG, and HDL-c increased by 12.49%, 15.01%, 14.93%, and 08.27%, respectively, and at 12 months these increased by 22%, 22.67%, 56.39%, and 14.98%, respectively, (P < 0.05). At the baseline, the mean fasting blood glucose (FBG) was 83.78 mg/dL while at 6 months and 12 months, the mean FBG was 88.18 mg/dL and 93.03 mg/dL, respectively, (P < 0.05). FBG was impaired in 11.9% and 17.8% of the patients at 6 months and 12 months, respectively. Diabetes was diagnosed in 4% of the patients at 12 months. Conclusion: ART has significant metabolic complications such as dyslipidemia, glucose intolerance, and increased body mass index (BMI) and requires proper monitoring and dose adjustment.