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Salman Y. Jabri

Amgen

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Publication

Featured researches published by Salman Y. Jabri.

Bioorganic & Medicinal Chemistry Letters | 2008

Tricyclic HIV integrase inhibitors: potent and orally bioavailable C5-aza analogs.

Haolun Jin; Matthew Blake Wright; Richard Pastor; Michael R. Mish; Sammy Metobo; Salman Y. Jabri; Rachael Lansdown; Ruby Cai; Peter Pyun; Manuel Tsiang; Xiaowu Chen; Choung U. Kim

A series of C5-aza tricyclic HIV integrase inhibitors was prepared. A highly potent and orally bioavailable compound (compound 9) was identified and selected for development.

Bioorganic & Medicinal Chemistry Letters | 2009

Tricyclic HIV integrase inhibitors V. SAR studies on the benzyl moiety

Haolun Jin; Sammy Metobo; Salman Y. Jabri; Michael R. Mish; Rachael Lansdown; Xiaowu Chen; Manuel Tsiang; Matthew Blake Wright; Choung U. Kim

SAR studies on the para-fluorobenzyl moiety of tricyclic HIV integrase inhibitors are discussed and lead compounds with potency and PK properties comparable to raltegravir were identified.

Archive | 2006

Integrase inhibitor compounds

Zhenhong R. Cai; Salman Y. Jabri; Haolun Jin; Choung U. Kim; Rachael Lansdown; Samuel E. Metobo; Michael R. Mish; Richard Pastor

Bioorganic & Medicinal Chemistry Letters | 2006

Design, synthesis, and SAR studies of novel and highly active tri-cyclic HIV integrase inhibitors.

Haolun Jin; Ruby Cai; Laura N. Schacherer; Salman Y. Jabri; Manuel Tsiang; Maria Fardis; Xiaowu Chen; James M. Chen; Choung U. Kim

Bioorganic & Medicinal Chemistry Letters | 2006

Effect of substitution on novel tricyclic HIV-1 integrase inhibitors.

Maria Fardis; Haolun Jin; Salman Y. Jabri; Ruby Cai; Michael R. Mish; Manuel Tsiang; Choung U. Kim

Archive | 2005

Phosphonate analogs of HIV integrase inhibitor compounds

Zhenhong R. Cai; Xiaowu Chen; Maria Fardis; Salman Y. Jabri; Haolun Jin; Choung U. Kim; Sanuel E. Metobo; Michael R. Mish; Richard Pastor

Bioorganic & Medicinal Chemistry Letters | 2009

Tricyclic HIV integrase inhibitors: VI. SAR studies of ‘benzyl flipped’ C3-substituted pyrroloquinolines

Sammy Metobo; Michael R. Mish; Haolun Jin; Salman Y. Jabri; Rachael Lansdown; Xiaowu Chen; Manuel Tsiang; Matthew Blake Wright; Choung U. Kim

Archive | 2006

HIV-INTEGRASE INHIBITOR COMPOUNDS

Zhenhong R. Cai; Salman Y. Jabri; Haolun Jin; Choung U. Kim; Rachael Lansdown; Samuel E. Metobo; Michael R. Mish; Richard Pastor

Tetrahedron Letters | 2013

Highly regioselective ring opening of quinolinic[2,3]anhydrides under mild conditions

Sammy Metobo; Salman Y. Jabri; Evangelos Aktoudianakis; Jared Evans; Haolun Jin; Choung U. Kim

Archive | 2006

Antiviral phosphonate conjugates for inhibition of hiv

Zhenhong R. Cai; Salman Y. Jabri; Haolun Jin; Choung U. Kim; Samuel E. Metobo; Michael R. Mish; Richard Pastor

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Richard Pastor

Genentech

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Choung U. Kim

Academy of Sciences of the Czech Republic

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Xiaowu Chen

Fuzhou University

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Choung U. Kim

Academy of Sciences of the Czech Republic

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Matthew Blake Wright

Hoffmann-La Roche

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James M. Chen

DuPont

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Laura N. Schacherer

Yale University

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