Samir H. Mody

Meaningful Change and Responsiveness in Common Physical Performance Measures in Older Adults

OBJECTIVES: To estimate the magnitude of small meaningful and substantial individual change in physical performance measures and evaluate their responsiveness.

Daily cost of an intensive care unit day: the contribution of mechanical ventilation.

Objective:To quantify the mean daily cost of intensive care, identify key factors associated with increased cost, and determine the incremental cost of mechanical ventilation during a day in the intensive care unit. Design:Retrospective cohort analysis using data from NDCHealth’s Hospital Patient Level Database. Setting:A total of 253 geographically diverse U.S. hospitals. Patients:The study included 51,009 patients ≥18 yrs of age admitted to an intensive care unit between October 1, 2002, and December 31, 2002. Interventions:None. Measurements and Main Results:Days of intensive care and mechanical ventilation were identified using billing data, and daily costs were calculated as the sum of daily charges multiplied by hospital-specific cost-to-charge ratios. Cost data are presented as mean (±sd). Incremental daily cost of mechanical ventilation was calculated using log-linear regression, adjusting for patient and hospital characteristics. Approximately 36% of identified patients were mechanically ventilated at some point during their intensive care unit stay. Mechanically ventilated patients were older (63.5 yrs vs. 61.7 yrs, p < .0001) and more likely to be male (56.1% vs. 51.8%, p < 0.0001), compared with patients who were not mechanically ventilated, and required mechanical ventilation for a mean duration of 5.6 days ± 9.6. Mean intensive care unit cost and length of stay were

Antimicrobial Therapy Escalation and Hospital Mortality Among Patients With Health-Care-Associated Pneumonia: A Single-Center Experience

31,574 ± 42,570 and 14.4 days ± 15.8 for patients requiring mechanical ventilation and

Interpreting score differences in the SF-36 Vitality scale: using clinical conditions and functional outcomes to define the minimally important difference

12,931 ± 20,569 and 8.5 days ± 10.5 for those not requiring mechanical ventilation. Daily costs were greatest on intensive care unit day 1 (mechanical ventilation,

Prescription Opioid Abuse: A Literature Review of the Clinical and Economic Burden in the United States

10,794; no mechanical ventilation,

Cost-effectiveness of rivaroxaban compared with enoxaparin plus a vitamin K antagonist for the treatment of venous thromboembolism

6,667), decreased on day 2 (mechanical ventilation:,

Imipenem resistance of Pseudomonas in pneumonia: a systematic literature review

4,796; no mechanical ventilation,

Estimating the economic impact of a half-day reduction in length of hospital stay among patients with community-acquired pneumonia in the US

3,496), and became stable after day 3 (mechanical ventilation,

Dosing patterns, hematologic outcomes, and costs of erythropoietic agents in predialysis chronic kidney disease patients with anemia

3,968; no mechanical ventilation,

Anaemia and the Risk of Injurious Falls in a Community-Dwelling Elderly Population

3,184). Adjusting for patient and hospital characteristics, the mean incremental cost of mechanical ventilation in intensive care unit patients was